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I am developing Catalyst.jl (https://github.com/SciML/Catalyst.jl) for systems biology modelling. Likelihood profiles are used in Systems biology for practical identifiability analysis, and in the community we are looking for a good Julia tool for computing this, and this package looks neat!
A question, is there (or would it be possible to get) and option for computing the full profile over an interval (p_start,p_end). Here, rather than having a confidence interval for the parameter, I would want to look at its full profile (which admittedly requires some more computation).
Does this make sense, and would this be something that could be supported?
The text was updated successfully, but these errors were encountered:
That shouldn't be too hard to implement. It might even be possible already if you set param_ranges appropriately with threshold=-Inf? Maybe you can check if that works.
If it doesn't work, I can try and find some time to get to it, although no guarantees just yet on when I might find the time (unless you want to work on a PR which I'm happy to assist with, although I really need to clean up the code significantly since it might be hard for you to read).
That shouldn't be too hard to implement. It might even be possible already if you set param_ranges appropriately with threshold=-Inf? Maybe you can check if that works.
This might work, I will play around with it. I'm playing around with the package right now, if I get familiar enough with it I could try make a PR at some point.
Hello!
I am developing Catalyst.jl (https://github.com/SciML/Catalyst.jl) for systems biology modelling. Likelihood profiles are used in Systems biology for practical identifiability analysis, and in the community we are looking for a good Julia tool for computing this, and this package looks neat!
A question, is there (or would it be possible to get) and option for computing the full profile over an interval
(p_start,p_end)
. Here, rather than having a confidence interval for the parameter, I would want to look at its full profile (which admittedly requires some more computation).Does this make sense, and would this be something that could be supported?
The text was updated successfully, but these errors were encountered: