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        Niklas Neubrand edited this page Jan 17, 2025 
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    This section contains articles which facilitate getting started with D2D.
- Video illustrating fitting
 - Installation and system requirements
 - First steps
 - Setting up models
 - How is the architecture of the code and the most important commands?
 - What are the most important fields of the global variable ar?
 - What are the most important functions?
 - Uncertainty analysis
 
This section contains a list of many advanced functionalities implemented in D2D.
- Estimating Prediction Uncertainty
 - Computation of integration-based prediction bands
 - Discrete Sampling of True Prediction Bands
 - L1 regularization
 - Input estimation
 - MCMC methods and functions
 - Retarded Transient Function
 - Moment ODE model
 - Priors
 - Objective function, likelihood and chi-square in the D2D framework
 - Time delay modelling using the linear chain trick
 - Structural identifiability and observability analysis for nonlinear dynamic models
 - Experimental Design
 
- Adapting the PLE Settings
 - Resetting the solver upon step input
 - Integrator Tolerances
 - Meaning of ar.config.fiterrors?
 - Optimization algorithms available in the D2D-framework
 - PLE calculations on a Cluster?
 - Parallelization
 - Parallelization of multi start optimization
 - bwCluster Calculations
 - Optimization Guidelines
 
- Advanced events and pre-equilibration
 - Distributed computing
 - Steady state constraints
 - Bolus injection
 - Bolus injection and washing
 - Partial differential equations
 - PEtab support
 - Model selection with PEtab Select
 - I get the error "Error C2011 'timespec': 'struct' type redefinition" while compiling
 - Solving issues with Ceres
 - Setup, compilation, configuration and transfer between systems
 - Spline Example: A Modulating Input Function
 - Using an older release version of D2D
 - Utilizing Example Collection
 - What's the meaning of ar.config.ploterrors?
 
This section contains some examples of models for which D2D was or can be utilized.
- Overview of application examples
 - Bachmann model in more detail
 - Becker model in more detail
 - Beer model in more detail
 - Boehm model in more detail
 - Merkle model in more detail
 - Lucarelli model in more detail
 - Raia model in more detail
 - Swameye model in more detail
 
Copyright © 2016 D2D development team. All rights reserved. Copyright text and third party software license information.
- Installation and system requirements
 - Setting up models
 - First steps
 - Advanced events and pre-equilibration
 - Computation of integration-based prediction bands
 
- How is the architecture of the code and the most important commands?
 - What are the most important fields of the global variable ar?
 - What are the most important functions?
 - Optimization algorithms available in the d2d-framework
 - Objective function, likelhood and chi-square in the d2d framework
 - How to set up priors?
 - How to set up steady state constraints?
 - How do I restart the solver upon a step input?
 - How to deal with integrator tolerances?
 - How to implement a bolus injection?
 - How to implement washing and an injection?
 - How to implement a moment ODE model?
 - How to run PLE calculations on a Cluster?