DIAMetric: TIC sum for each isolation window

[dtabb73]

What is the QC term's name?

TIC sum for each isolation window

Briefly describe the QC term.

MS:1000285 can report the TIC spanning across all MS scans collected in an LC-MS/MS run. This metric is intended to sum TIC across all MS/MS scans collected for a particular isolation window in a DIA experiment. As a result, it has one member of the tuple for each defined isolation window.

What is the QC term's unit?

Intensity unit

Value type

MS:4000004 ! n-tuple

Describe any additional information.

No response

[bittremieux]

Proposed CV term:

[Term]
id: MS:4000XXX
name: MS2 total ion current per isolation window
def: "Reports the summed total ion current (TIC) across all MS2 scans collected for each DIA isolation window in a run. Each table row represents one isolation window, described by its minimum and maximum m/z boundaries and the corresponding TIC value, enabling quantitative assessment of signal distribution across the DIA scheme."
is_a: MS:4000XXX ! intensity stability metric
relationship: part_of_workflow_stage MS:4000XXX ! MS2 acquisition stage
relationship: depends_on_data_type MS:4000XXX ! raw acquisition data
relationship: has_measurement_scope MS:4000XXX ! run level
relationship: applies_to_acquisition_mode MS:4000XXX ! data-independent acquisition
relationship: has_quality_directionality MS:4000XXX ! higher is better
relationship: has_value_type MS:4000XXX ! table
relationship: has_column MS:1000828 ! isolation window lower offset
relationship: has_column MS:1000829 ! isolation window upper offset
relationship: has_column MS:1000285 ! total ion current