The COSICC R package can be installed using the devtools R package as follows.

if(!require(devtools)){ install.packages("devtools") }

if(!require(BiocManager)){ install.packages("BiocManager") }

options(repos = BiocManager::repositories())

BiocManager::install("scRNAseq")

devtools::install_github("https://github.com/theislab/destiny",dependencies = TRUE)

devtools::install_github("https://github.com/MarioniLab/COSICC",dependencies = TRUE, upgrade = TRUE,build_vignettes = TRUE)

There is a pfd vignette calledd Intro_to_COSICC_pdf.pdf.

Once the R package has been installed, a vignette can also be accessed by typing vignette("Intro_to_COSICC",package="COSICC").