diff --git a/MANIFEST.in b/MANIFEST.in
new file mode 100644
index 0000000..3b1a32b
--- /dev/null
+++ b/MANIFEST.in
@@ -0,0 +1 @@
+include ptm_pose/Resource_Files/modification_conversion.csv
\ No newline at end of file
diff --git a/setup.py b/setup.py
new file mode 100644
index 0000000..b670719
--- /dev/null
+++ b/setup.py
@@ -0,0 +1,24 @@
+from setuptools import setup, find_packages
+
+
+# Run setup
+setup(
+    name="ptm_pose",
+    version="0.1.0",
+    author="Naegle Lab",
+    author_email="kmn4mj@virginia.edu",
+    url="https://github.com/NaegleLab/PTM-POSE/tree/main",
+    install_requires=['pandas==2.2.*', 'numpy==1.26.*', 'scipy=1.13.*', 'biopython==1.83.*', 'tqdm==4.66.*', 'xlrd', 'matplotlib', 'requests'],
+    license='GNU General Public License v3',
+    description='PTM-POSE: PTM Projection onto Splice Events',
+    long_description="""PTM-POSE is an open-source tool for annotating splice event quantification data with post-translational modifications (PTMs) and their functional consequences.""",
+    classifiers=[
+        "Programming Language :: Python :: 3",
+        "Intended Audience :: Science/Research",
+        "Operating System :: OS Independent",
+    ],
+    packages=find_packages(),
+    include_package_data = True,
+    python_requires=">=3.9"
+)
+