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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Zenos.AI</title>
<link rel="preconnect" href="https://fonts.googleapis.com">
<link rel="preconnect" href="https://fonts.gstatic.com" crossorigin>
<link href="https://fonts.googleapis.com/css2?family=Roboto:wght@400;700&display=swap" rel="stylesheet">
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/6.4.0/css/all.min.css">
<link rel="stylesheet" href="css/base.css">
<link rel="stylesheet" href="css/typography.css">
<link rel="stylesheet" href="css/components.css">
</head>
<body>
<div id="nav-placeholder"></div>
<script src="js/component-loader.js"></script>
<script src="js/nav.js"></script>
<header class="hero-section">
<img src="/Zenos.AI.github.io/Images/Logo.png" alt="Zenos.AI Logo" class="hero-image">
<h1><span class="main-text">Zenos</span><span class="accent">.AI</span></h1>
<p class="tagline">
Computational Physiology Without Limits
</p>
</header>
<main>
<div class="section-separator"></div>
<section class="content-section">
<h2>Models of Physiology</h2>
<p class="pjust">
Whether it's engineering the next generation of human-centric products, developing safer protective gear, or designing more efficient
physical training programs, models of human physiology can provide you with <span class="white-bold">new insights</span>, while <span class="white-bold">limiting the need for resource-intensive
experimental testing</span>.
</p>
</section>
<div class="section-separator"></div>
<section class="content-section">
<h2>Lack of Alternatives</h2>
<p class="pjust">
Unfortunately, current methods for modeling human physiology are <span class="white-bold">severely limited</span>.
They often rely on <span class="white-bold">purely statistically derived</span>,
and <span class="white-bold">isolated</span> physiological mechanisms.
</p>
<div class="card-container">
<div class="card">
<h3>Why is this a Problem?</h3>
<ul>
<li class="has-details">
Some variables are non-measurable
<div class="details-content">
The existence of non-measurable variables implies that models <strong>cannot be fit on all underlying subprocesses</strong>.
E.g. we cannot (yet) measure the neural mechanisms of sweat secretion. This is <strong>highly problematic</strong>
when good data quality and quantity cannot be assured.
</div>
</li>
<li class="has-details">
Few scenarios are measured
<div class="details-content">
Regarding the data quality, one aspect is the diversity. <strong>The diversity of experimental scenarios is low.</strong>
E.g. we do not have data at every possible combination of humidity, exercise intensity, and temperature. But most problematic
is that <strong>data regarding extreme scenarios is super scarce, or even absent.</strong>
</div>
</li>
<li class="has-details">
Datasets are small and noisy
<div class="details-content">
Experiments often measure a <strong>few variables at a time on a very limited amount of participants.</strong> When one variable
is measured, another variable is absent, and so on. The <strong>collected data is also inherently noisy</strong>, as the human body is
non-deterministic.
</div>
</li>
<li class="has-details">
The body is complex and integrated
<div class="details-content">
Human physiology is a function of trillions of cells that constantly interact. Therefore,
<strong>describing physiological mechanisms in isolation might be too simplistic.</strong>
</div>
</li>
</ul>
</div>
<div class="card">
<h3>What are the Consequences?</h3>
<ul>
<li class="has-details">
Low generalizability
<div class="details-content">
Due to limited and flawed training data in addition to the use of non-mechanism based models, <strong>significant out of
context errors might be expected.</strong> For example, the literature reports a <strong>1.7 - 2.8x</strong> increase in error
with <strong>ONLY</strong> slight shifts in exercise intensity (Psikuta et al., 2011).
</div>
</li>
<li class="has-details">
Scenarios cannot be modeled
<div class="details-content">
Scenarios that include manipulation of variables that are not included in the non-mechanism based models,
<strong>cannot be modeled.</strong> An example is the thermophysiological response in case of high blood loss.
</div>
</li>
<li class="has-details">
Limited actionable insights
<div class="details-content">
As models are not based on real working mechanisms, <strong>no informative feedback can be provided.</strong>
Important questions remain; <em>Why are the results as observed?</em> and <em>How can we improve our product/strategy?</em>
</div>
</li>
</ul>
</div>
</div>
</section>
<div class="section-separator"></div>
<section class="content-section">
<h2> <i class="fa-solid fa-bolt blue-icon"></i> Our Solution <i class="fa-solid fa-bolt blue-icon"></i> </h2>
<p class="pjust">
<span class="white-bold">Zenos.AI will offer a model that changes the game</span>. We will combine statistical methods, multidimensional data, and
huge amounts of domain knowledge to create a <span class="white-bold">more informative and better generalizable model</span> of the human body.
<br>
<br>
In this way <span class="white-bold">Zenos.AI</span> will not just become another mediocre research tool, but a
<span class="white-bold">holistic framework</span> that gives you a complete and accurate picture of human physiology.
</p>
</section>
<div class="section-separator"></div>
<section class="content-section">
<h2>Key Features</h2>
<div class="section-grid">
<div class="grid-item">
<img src="Images/Arrow.png" alt="Arrow Icon">
<h3>Improved Accuracy</h3>
<p>Enjoy more stable model performance across conditions.</p>
</div>
<div class="grid-item">
<img src="Images/SwissKnife.png" alt="SwissKnife Icon">
<h3>Wider Application Domain</h3>
<p>Play with and manipulate components of the human body, and watch their effects unfold in real time.</p>
</div>
<div class="grid-item">
<img src="Images/Insights.png" alt="Insights">
<h3>Actionable Insights</h3>
<p>Have access to unprecedented information on underlying processes. </p>
</div>
<div class="grid-item">
<img src="Images/Save.png" alt="Save">
<h3>Save Resources</h3>
<p>Test new hypotheses, and save resources by optimizing products, and plans in simulation. </p>
</div>
</div>
</section>
<div class="section-separator"></div>
<section class="content-section">
<h2>Who Is This For?</h2>
<div class="section-grid">
<div class="grid-item">
<img src="Images/Engineer.png" alt="Engineer Icon">
<h3>Engineers</h3>
<p>Ensure that the product has the intended effect on the user, or does not negatively impact the user.</p>
</div>
<div class="grid-item">
<img src="Images/Organizer.png" alt="Organizer Icon">
<h3>Event Organizers</h3>
<p>Minimize health-related risks by performing simulations for the expected environmental conditions.</p>
</div>
<div class="grid-item">
<img src="Images/Physical.png" alt="Physical Icon">
<h3>Physical Training</h3>
<p>Increase the accuracy of training load quantification, the design of training sessions, and pacing strategies.</p>
</div>
<div class="grid-item">
<img src="Images/HealthCare.png" alt="Health Care Icon">
<h3>Health Care</h3>
<p>Evaluate the impacts of surgery or improvement of function (e.g. cardiac output) on the physiological system, and assess the risks of exercise and environmental conditions for patients.</p>
</div>
<div class="grid-item">
<img src="Images/Researcher.png" alt="Researcher Icon">
<h3>Researchers</h3>
<p>Develop and test hypotheses, (pre-)simulate experiments, and build models on top of a whole body model.</p>
</div>
</div>
</section>
<div class="section-separator"></div>
<section class="content-section">
<h2>Roadmap</h2>
</section>
<img src="Images/TimeLine.png" alt="Timeline" class="Roadmap-image">
<div class="section-separator"></div>
<section class="content-section">
<h2>Be the First to Know</h2>
<p>Join our early access list to get updates and be notified when we launch.</p>
<form class="notify-container" action="https://formspree.io/f/xzzvnayy" method="POST">
<input type="email" name="email" placeholder="Enter your email" required>
<button type="submit">Notify Me</button>
</form>
</section>
</main>
</body>
</html>