diff --git a/monai/data/image_reader.py b/monai/data/image_reader.py
index 515bf38a39..9438582656 100644
--- a/monai/data/image_reader.py
+++ b/monai/data/image_reader.py
@@ -1112,6 +1112,8 @@ def get_data(self, img) -> tuple[np.ndarray, dict]:
 
         for i, filename in zip(ensure_tuple(img), self.filenames):
             header = self._get_meta_dict(i)
+            if MetaKeys.PIXDIM in header:
+                header[MetaKeys.ORIGINAL_PIXDIM] = np.array(header[MetaKeys.PIXDIM], copy=True)
             header[MetaKeys.AFFINE] = self._get_affine(i)
             header[MetaKeys.ORIGINAL_AFFINE] = self._get_affine(i)
             header["as_closest_canonical"] = self.as_closest_canonical
diff --git a/monai/transforms/inverse.py b/monai/transforms/inverse.py
index 2f57f4614a..ecf918f47a 100644
--- a/monai/transforms/inverse.py
+++ b/monai/transforms/inverse.py
@@ -22,7 +22,7 @@
 from monai import transforms
 from monai.data.meta_obj import MetaObj, get_track_meta
 from monai.data.meta_tensor import MetaTensor
-from monai.data.utils import to_affine_nd
+from monai.data.utils import affine_to_spacing, to_affine_nd
 from monai.transforms.traits import InvertibleTrait
 from monai.transforms.transform import Transform
 from monai.utils import (
@@ -224,6 +224,9 @@ def track_transform_meta(
                 else:
                     raise
             out_obj.meta[MetaKeys.AFFINE] = convert_to_tensor(affine, device=torch.device("cpu"), dtype=torch.float64)
+            if MetaKeys.PIXDIM in out_obj.meta:
+                spacing = affine_to_spacing(out_obj.meta[MetaKeys.AFFINE])
+                out_obj.meta[MetaKeys.PIXDIM][1 : 1 + len(spacing)] = spacing
 
         if not (get_track_meta() and transform_info and transform_info.get(TraceKeys.TRACING)):
             if isinstance(data, Mapping):
diff --git a/monai/transforms/spatial/dictionary.py b/monai/transforms/spatial/dictionary.py
index a61d794183..c1a10957c2 100644
--- a/monai/transforms/spatial/dictionary.py
+++ b/monai/transforms/spatial/dictionary.py
@@ -29,6 +29,7 @@
 from monai.data.box_utils import BoxMode, StandardMode
 from monai.data.meta_obj import get_track_meta
 from monai.data.meta_tensor import MetaTensor
+from monai.data.utils import is_supported_format
 from monai.networks.layers.simplelayers import GaussianFilter
 from monai.transforms.croppad.array import CenterSpatialCrop
 from monai.transforms.inverse import InvertibleTransform
@@ -521,6 +522,13 @@ def __call__(self, data: Mapping[Hashable, torch.Tensor], lazy: bool | None = No
                 output_spatial_shape=output_shape_k if should_match else None,
                 lazy=lazy_,
             )
+            if isinstance(d[key], MetaTensor):
+                meta_keys = [k for k in d.keys() if k is not None and k.startswith(f"{key}_")]
+                for meta_key in meta_keys:
+                    if "filename_or_obj" in d[key].meta and is_supported_format(
+                        d[key].meta["filename_or_obj"], ["nii", "nii.gz"]
+                    ):
+                        d[meta_key].update(d[key].meta)
             if output_shape_k is None:
                 output_shape_k = d[key].peek_pending_shape() if isinstance(d[key], MetaTensor) else d[key].shape[1:]
         return d
diff --git a/monai/utils/enums.py b/monai/utils/enums.py
index f5bb6c4c5b..be00b27d73 100644
--- a/monai/utils/enums.py
+++ b/monai/utils/enums.py
@@ -542,6 +542,8 @@ class MetaKeys(StrEnum):
     Typical keys for MetaObj.meta
     """
 
+    PIXDIM = "pixdim"  # MetaTensor.pixdim
+    ORIGINAL_PIXDIM = "original_pixdim"  # the pixdim after image loading before any data processing
     AFFINE = "affine"  # MetaTensor.affine
     ORIGINAL_AFFINE = "original_affine"  # the affine after image loading before any data processing
     SPATIAL_SHAPE = "spatial_shape"  # optional key for the length in each spatial dimension