The 13th Mexican Conference on Pattern Recognition (MCPR2021) will be held in Mexico City, Mexico from June 23 to June 26, 2021, under direction of the Academic Division of Engineering of the Instituto Tecnológico Autónomo de México (ITAM), jointly with Coordinación de Ciencias Computacionales of Instituto Nacional de Astrófísica Óptica y Electrónica (INAOE), and with the consent of the International Association of Pattern Recognition (IAPR). MCPR2021 attempts to provide a forum for the exchange of scientific results, experiences, and new knowledge, as well as, promoting co-operation among research groups in Pattern Recognition and related areas in Mexico and around the world.