diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 6d2e6add0e6c5..baa3b148ebf65 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -72,7 +72,7 @@ jobs:
         run: |
           # Run tests on commits after the last merge commit and before the PR head commit
           # Use clang++, because it is a bit faster and uses less memory than g++
-          git rebase --exec "echo Running test-one-commit on \$( git log -1 ) && CC=clang CXX=clang++ cmake -B build -DWERROR=ON -DWITH_MULTIPROCESS=OFF -DBUILD_BENCH=ON -DBUILD_FUZZ_BINARY=ON -DCMAKE_CXX_FLAGS='-Wno-error=unused-member-function' && cmake --build build -j $(nproc) && ctest --output-on-failure --stop-on-failure --test-dir build -j $(nproc) && ./build/test/functional/test_runner.py -j $(( $(nproc) * 2 ))" ${{ env.TEST_BASE }}
+          git rebase --exec "echo Running test-one-commit on \$( git log -1 ) && CC=clang CXX=clang++ cmake -B build -DWERROR=ON -DWITH_MULTIPROCESS=OFF -DWITH_SV2=OFF -DBUILD_BENCH=ON -DBUILD_FUZZ_BINARY=ON -DCMAKE_CXX_FLAGS='-Wno-error=unused-member-function' && cmake --build build -j $(nproc) && ctest --output-on-failure --stop-on-failure --test-dir build -j $(nproc) && ./build/test/functional/test_runner.py -j $(( $(nproc) * 2 ))" ${{ env.TEST_BASE }}
 
   macos-native-arm64:
     name: ${{ matrix.job-name }}
diff --git a/ci/test/00_setup_env_native_asan.sh b/ci/test/00_setup_env_native_asan.sh
index d61cf14d18360..784e4d823a8ce 100755
--- a/ci/test/00_setup_env_native_asan.sh
+++ b/ci/test/00_setup_env_native_asan.sh
@@ -25,6 +25,7 @@ export NO_DEPENDS=1
 export GOAL="install"
 export BITCOIN_CONFIG="\
  -DWITH_MULTIPROCESS=OFF \
+ -DWITH_SV2=OFF \
  -DSANITIZERS=address,float-divide-by-zero,integer,undefined \
  -DCMAKE_C_COMPILER=clang-${APT_LLVM_V} \
  -DCMAKE_CXX_COMPILER=clang++-${APT_LLVM_V} \
diff --git a/ci/test/00_setup_env_native_fuzz.sh b/ci/test/00_setup_env_native_fuzz.sh
index cd67fabb9203e..0474451aedefd 100755
--- a/ci/test/00_setup_env_native_fuzz.sh
+++ b/ci/test/00_setup_env_native_fuzz.sh
@@ -17,6 +17,7 @@ export RUN_FUZZ_TESTS=true
 export GOAL="install"
 export CI_CONTAINER_CAP="--cap-add SYS_PTRACE"  # If run with (ASan + LSan), the container needs access to ptrace (https://github.com/google/sanitizers/issues/764)
 export BITCOIN_CONFIG="\
+ -DWITH_SV2=OFF \
  -DBUILD_FOR_FUZZING=ON \
  -DSANITIZERS=fuzzer,address,undefined,float-divide-by-zero,integer \
  -DCMAKE_C_COMPILER=clang-${APT_LLVM_V} \
diff --git a/depends/toolchain.cmake.in b/depends/toolchain.cmake.in
index 8d3219df5bb04..b7abb1e0d4f0c 100644
--- a/depends/toolchain.cmake.in
+++ b/depends/toolchain.cmake.in
@@ -155,6 +155,7 @@ endif()
 set(multiprocess_packages @multiprocess_packages@)
 if("${multiprocess_packages}" STREQUAL "")
   set(WITH_MULTIPROCESS OFF CACHE BOOL "")
+  set(WITH_SV2 OFF CACHE BOOL "")
 else()
   set(WITH_MULTIPROCESS ON CACHE BOOL "")
   set(Libmultiprocess_ROOT "${CMAKE_CURRENT_LIST_DIR}" CACHE PATH "")