diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index a60adc5eaa24f..0bba735dc0a73 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -81,7 +81,7 @@ jobs:
         run: |
           # Run tests on commits after the last merge commit and before the PR head commit
           # Use clang++, because it is a bit faster and uses less memory than g++
-          git rebase --exec "echo Running test-one-commit on \$( git log -1 ) && CC=clang CXX=clang++ cmake -B build -DWERROR=ON -DWITH_ZMQ=ON -DBUILD_GUI=ON -DBUILD_BENCH=ON -DBUILD_FUZZ_BINARY=ON -DWITH_BDB=ON -DWITH_USDT=ON -DCMAKE_CXX_FLAGS='-Wno-error=unused-member-function' && cmake --build build -j $(nproc) && ctest --output-on-failure --stop-on-failure --test-dir build -j $(nproc) && ./build/test/functional/test_runner.py -j $(( $(nproc) * 2 )) --combinedlogslen=99999999" ${{ env.TEST_BASE }}
+          git rebase --exec "echo Running test-one-commit on \$( git log -1 ) && CC=clang CXX=clang++ cmake -B build -DWERROR=ON -DWITH_MULTIPROCESS=ON -DWITH_ZMQ=ON -DBUILD_GUI=ON -DBUILD_BENCH=ON -DBUILD_FUZZ_BINARY=ON -DWITH_BDB=ON -DWITH_USDT=ON -DCMAKE_CXX_FLAGS='-Wno-error=unused-member-function' && cmake --build build -j $(nproc) && ctest --output-on-failure --stop-on-failure --test-dir build -j $(nproc) && ./build/test/functional/test_runner.py -j $(( $(nproc) * 2 )) --combinedlogslen=99999999" ${{ env.TEST_BASE }}
 
   macos-native-arm64:
     name: ${{ matrix.job-name }}
diff --git a/ci/test/00_setup_env_mac_native.sh b/ci/test/00_setup_env_mac_native.sh
index e01a56895bfb6..198c3c2ef11c0 100755
--- a/ci/test/00_setup_env_mac_native.sh
+++ b/ci/test/00_setup_env_mac_native.sh
@@ -11,7 +11,13 @@ export LC_ALL=C.UTF-8
 export PIP_PACKAGES="--break-system-packages zmq"
 export GOAL="install"
 export CMAKE_GENERATOR="Ninja"
-export BITCOIN_CONFIG="-DBUILD_GUI=ON -DWITH_ZMQ=ON -DREDUCE_EXPORTS=ON"
+export BITCOIN_CONFIG="\
+-DWITH_MULTIPROCESS=ON \
+-DBUILD_GUI=ON \
+-DWITH_ZMQ=ON \
+-DREDUCE_EXPORTS=ON \
+"
 export CI_OS_NAME="macos"
 export NO_DEPENDS=1
 export OSX_SDK=""
+export BITCOIND=bitcoin-node # Used in functional tests
diff --git a/ci/test/00_setup_env_native_asan.sh b/ci/test/00_setup_env_native_asan.sh
index e78c593701978..8147f69e51d14 100755
--- a/ci/test/00_setup_env_native_asan.sh
+++ b/ci/test/00_setup_env_native_asan.sh
@@ -24,7 +24,12 @@ export PACKAGES="systemtap-sdt-dev clang-${APT_LLVM_V} llvm-${APT_LLVM_V} libcla
 export NO_DEPENDS=1
 export GOAL="install"
 export BITCOIN_CONFIG="\
- -DWITH_USDT=ON -DWITH_ZMQ=ON -DWITH_BDB=ON -DWARN_INCOMPATIBLE_BDB=OFF -DBUILD_GUI=ON \
+ -DWITH_MULTIPROCESS=ON \
+ -DWITH_USDT=ON \
+ -DWITH_ZMQ=ON \
+ -DWITH_BDB=ON \
+ -DWARN_INCOMPATIBLE_BDB=OFF \
+ -DBUILD_GUI=ON \
  -DSANITIZERS=address,float-divide-by-zero,integer,undefined \
  -DCMAKE_C_COMPILER=clang-${APT_LLVM_V} \
  -DCMAKE_CXX_COMPILER=clang++-${APT_LLVM_V} \
diff --git a/ci/test/00_setup_env_native_fuzz_with_valgrind.sh b/ci/test/00_setup_env_native_fuzz_with_valgrind.sh
index f453054b7f0a8..ed3f2cc645bda 100755
--- a/ci/test/00_setup_env_native_fuzz_with_valgrind.sh
+++ b/ci/test/00_setup_env_native_fuzz_with_valgrind.sh
@@ -16,6 +16,7 @@ export RUN_FUZZ_TESTS=true
 export FUZZ_TESTS_CONFIG="--valgrind"
 export GOAL="install"
 export BITCOIN_CONFIG="\
+ -DWITH_MULTIPROCESS=ON \
  -DBUILD_FOR_FUZZING=ON \
  -DSANITIZERS=fuzzer \
  -DCMAKE_C_COMPILER=clang-16 \
diff --git a/ci/test/00_setup_env_native_tidy.sh b/ci/test/00_setup_env_native_tidy.sh
index 4f79ff807fe69..98e6fe2b1c52f 100755
--- a/ci/test/00_setup_env_native_tidy.sh
+++ b/ci/test/00_setup_env_native_tidy.sh
@@ -19,7 +19,13 @@ export RUN_CHECK_DEPS=true
 export RUN_TIDY=true
 export GOAL="install"
 export BITCOIN_CONFIG="\
- -DWITH_ZMQ=ON -DBUILD_GUI=ON -DBUILD_BENCH=ON -DWITH_USDT=ON -DWITH_BDB=ON -DWARN_INCOMPATIBLE_BDB=OFF \
+ -DWITH_MULTIPROCESS=ON \
+ -DWITH_ZMQ=ON \
+ -DBUILD_GUI=ON \
+ -DBUILD_BENCH=ON \
+ -DWITH_USDT=ON \
+ -DWITH_BDB=ON \
+ -DWARN_INCOMPATIBLE_BDB=OFF \
  -DENABLE_HARDENING=OFF \
  -DCMAKE_C_COMPILER=clang-${TIDY_LLVM_V} \
  -DCMAKE_CXX_COMPILER=clang++-${TIDY_LLVM_V} \
diff --git a/ci/test/00_setup_env_native_tsan.sh b/ci/test/00_setup_env_native_tsan.sh
index d5afb6f2cf439..70f98fae325ed 100755
--- a/ci/test/00_setup_env_native_tsan.sh
+++ b/ci/test/00_setup_env_native_tsan.sh
@@ -13,5 +13,9 @@ export PACKAGES="clang-${APT_LLVM_V} llvm-${APT_LLVM_V} libclang-rt-${APT_LLVM_V
 export DEP_OPTS="CC=clang-${APT_LLVM_V} CXX='clang++-${APT_LLVM_V} -stdlib=libc++' MULTIPROCESS=1"
 export LIBMULTIPROCESS_CMAKE_OPTIONS="-DCMAKE_CXX_FLAGS=-fsanitize=thread"
 export GOAL="install"
-export BITCOIN_CONFIG="-DWITH_ZMQ=ON -DSANITIZERS=thread \
--DAPPEND_CPPFLAGS='-DARENA_DEBUG -DDEBUG_LOCKORDER -DDEBUG_LOCKCONTENTION -D_LIBCPP_REMOVE_TRANSITIVE_INCLUDES'"
+export BITCOIN_CONFIG="\
+-DWITH_MULTIPROCESS=ON \
+-DWITH_ZMQ=ON \
+-DSANITIZERS=thread \
+-DAPPEND_CPPFLAGS='-DARENA_DEBUG -DDEBUG_LOCKORDER -DDEBUG_LOCKCONTENTION -D_LIBCPP_REMOVE_TRANSITIVE_INCLUDES'\
+"
diff --git a/ci/test/00_setup_env_native_valgrind.sh b/ci/test/00_setup_env_native_valgrind.sh
index abf5fadc3ee23..5104388e25e7f 100755
--- a/ci/test/00_setup_env_native_valgrind.sh
+++ b/ci/test/00_setup_env_native_valgrind.sh
@@ -15,7 +15,11 @@ export TEST_RUNNER_EXTRA="--exclude feature_init,rpc_bind,feature_bind_extra"  #
 export GOAL="install"
 # TODO enable GUI
 export BITCOIN_CONFIG="\
- -DWITH_ZMQ=ON -DWITH_BDB=ON -DWARN_INCOMPATIBLE_BDB=OFF -DBUILD_GUI=OFF \
+ -DWITH_MULTIPROCESS=ON \
+ -DWITH_ZMQ=ON
+ -DWITH_BDB=ON
+ -DWARN_INCOMPATIBLE_BDB=OFF
+ -DBUILD_GUI=OFF \
  -DCMAKE_C_COMPILER=clang-16 \
  -DCMAKE_CXX_COMPILER=clang++-16 \
 "