diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 77b6e592..b47a1126 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -66222,7 +66222,7 @@
           - MAM01700c: 1
           - MAM01752c: 1
           - MAM01755c: -1
-      - lower_bound: -1000
+      - lower_bound: 0
       - upper_bound: 1000
       - gene_reaction_rule: "ENSG00000176890"
       - rxnFrom: "HMRdatabase"