From cefffae7750565766fd5f4433b19f2a652e9a449 Mon Sep 17 00:00:00 2001
From: Jiahao Luo <67491919+JHL-452b@users.noreply.github.com>
Date: Tue, 31 Dec 2024 09:45:39 +0800
Subject: [PATCH] fix: GPR curation for transport reactions (10)

---
 model/Human-GEM.yml | 68 ++++++++++++++++++++++-----------------------
 1 file changed, 34 insertions(+), 34 deletions(-)

diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 8e34d936..03821aba 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -161269,7 +161269,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161284,7 +161284,7 @@
           - MAM01253e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000108932 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161299,7 +161299,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161314,7 +161314,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161344,7 +161344,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161359,7 +161359,7 @@
           - MAM01253e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161389,7 +161389,7 @@
           - MAM01252e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161404,7 +161404,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161419,7 +161419,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161449,7 +161449,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161464,7 +161464,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161479,7 +161479,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161494,7 +161494,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161509,7 +161509,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161524,7 +161524,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161539,7 +161539,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161554,7 +161554,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161584,7 +161584,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161599,7 +161599,7 @@
           - MAM01306e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161614,7 +161614,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161629,7 +161629,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161644,7 +161644,7 @@
           - MAM01306e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161659,7 +161659,7 @@
           - MAM02403e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161674,7 +161674,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161689,7 +161689,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161704,7 +161704,7 @@
           - MAM01306e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000108932 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161719,7 +161719,7 @@
           - MAM01306e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161734,7 +161734,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161749,7 +161749,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161764,7 +161764,7 @@
           - MAM02403e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161779,7 +161779,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161794,7 +161794,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161809,7 +161809,7 @@
           - MAM01252e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161824,7 +161824,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem: