SynergyFinderR/DESCRIPTION at master · TangSoftwareLab/SynergyFinderR · GitHub

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Package: synergyfinder
Type: Package
Title: Calculate and Visualize Synergy Scores for Drug Combinations
Version: 3.7.4
Date: 2023-04-13
Authors@R:
  c(person(given = "Shuyu",
           family = "Zheng",
           role = c("aut", "cre"),
           email = "shuyu.zheng@helsinki.fi"
           ),
    person(given = "Jing",
           family = "Tang",
           role = c("aut"),
           email = "jing.tang@helsinki.fi"
           )
    )
Depends: R (>= 4.0.0)
Imports: drc (>= 3.0-1), reshape2 (>= 1.4.4), tidyverse (>= 1.3.0),
         dplyr (>= 1.0.3), tidyr (>= 1.1.2), purrr (>= 0.3.4), furrr (>= 0.2.2),
         ggplot2 (>= 3.3.3), ggforce (>= 0.3.2), grid (>= 4.0.2),
         vegan (>= 2.5-7), gstat (>= 2.0-6), sp (>= 1.4-5), methods (>= 4.0.2),
         SpatialExtremes (>= 2.0-9), ggrepel (>= 0.9.1), kriging (>= 1.1),
         plotly (>= 4.9.3), stringr (>= 1.4.0), future (>= 1.21.0),
         mice (>= 3.13.0), lattice (>= 0.20-41), nleqslv (>= 3.3.2),
         stats (>= 4.0.2), graphics (>= 4.0.2), grDevices (>= 4.0.2),
         magrittr (>= 2.0.1), pbapply (>= 1.4-3), metR (>= 0.9.1)
Description: Efficient implementations for analyzing pre-clinical multiple drug
  combination datasets. It provides efficient implementations for 1.the popular
  synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the
  degree of drug combination synergy; 2. higher order drug combination data
  analysis and synergy landscape visualization for unlimited number of drugs in a
  combination; 3. statistical analysis of drug combination synergy and
  sensitivity with confidence intervals and p-values; 4. synergy barometer for
  harmonizing multiple synergy scoring methods to provide a consensus metric of
  synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an
  unbiased interpretation of the clinical potential of the drug combinations.
  Based on this package, we also provide a web application
  (https://synergyfinder.org/) for users who prefer graphical user
  interface.
License: Mozilla Public License 2.0
Encoding: UTF-8
URL: https://synergyfinder.org/
RoxygenNote: 7.2.3
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biocViews: Software, StatisticalMethod