diff --git a/boards/arm/stm32f7/stm32f777zit6-meadow/configs/i2s/defconfig b/boards/arm/stm32f7/stm32f777zit6-meadow/configs/i2s/defconfig
new file mode 100644
index 0000000000000..efa714be6c19e
--- /dev/null
+++ b/boards/arm/stm32f7/stm32f777zit6-meadow/configs/i2s/defconfig
@@ -0,0 +1,79 @@
+#
+# This file is autogenerated: PLEASE DO NOT EDIT IT.
+#
+# You can use "make menuconfig" to make any modifications to the installed .config file.
+# You can then do "make savedefconfig" to generate a new defconfig file that includes your
+# modifications.
+#
+# CONFIG_STM32F7_USE_LEGACY_PINMAP is not set
+CONFIG_ARCH="arm"
+CONFIG_ARCH_BOARD="stm32f777zit6-meadow"
+CONFIG_ARCH_BOARD_MEADOW_F7MICRO=y
+CONFIG_ARCH_CHIP="stm32f7"
+CONFIG_ARCH_CHIP_STM32F777ZI=y
+CONFIG_ARCH_CHIP_STM32F7=y
+CONFIG_ARCH_STACKDUMP=y
+CONFIG_ARMV7M_DCACHE=y
+CONFIG_ARMV7M_DCACHE_WRITETHROUGH=y
+CONFIG_ARMV7M_DTCM=y
+CONFIG_ARMV7M_ICACHE=y
+CONFIG_AUDIO=y
+CONFIG_AUDIO_CS4344=y
+CONFIG_AUDIO_EXCLUDE_TONE=y
+CONFIG_AUDIO_EXCLUDE_VOLUME=y
+CONFIG_AUDIO_I2S=y
+CONFIG_BCH=y
+CONFIG_BOARDCTL_USBDEVCTRL=y
+CONFIG_BOARD_LATE_INITIALIZE=y
+CONFIG_BOARD_LOOPSPERMSEC=43103
+CONFIG_BUILTIN=y
+CONFIG_CDCACM=y
+CONFIG_CDCACM_CONSOLE=y
+CONFIG_CDCACM_PRODUCTID=0x0001
+CONFIG_CDCACM_PRODUCTSTR="Wilderness Labs"
+CONFIG_CDCACM_VENDORID=0x2E6A
+CONFIG_CDCACM_VENDORSTR="Meadow F7 Micro"
+CONFIG_CRYPTO=y
+CONFIG_CRYPTO_RANDOM_POOL=y
+CONFIG_DEV_URANDOM=y
+CONFIG_DEV_URANDOM_RANDOM_POOL=y
+CONFIG_DRIVERS_AUDIO=y
+CONFIG_FS_LITTLEFS=y
+CONFIG_HAVE_CXX=y
+CONFIG_HAVE_CXXINITIALIZE=y
+CONFIG_I2S=y
+CONFIG_INIT_ENTRYPOINT="nsh_main"
+CONFIG_INTELHEX_BINARY=y
+CONFIG_MM_REGIONS=3
+CONFIG_MTD=y
+CONFIG_MTD_BYTE_WRITE=y
+CONFIG_MTD_PARTITION=y
+CONFIG_MTD_SECT512=y
+CONFIG_MTD_W25QXXXJV=y
+CONFIG_NSH_ARCHINIT=y
+CONFIG_NSH_BUILTIN_APPS=y
+CONFIG_NSH_FILEIOSIZE=512
+CONFIG_NSH_LINELEN=64
+CONFIG_NSH_READLINE=y
+CONFIG_PREALLOC_TIMERS=4
+CONFIG_RAM_SIZE=245760
+CONFIG_RAM_START=0x20010000
+CONFIG_RAW_BINARY=y
+CONFIG_RR_INTERVAL=200
+CONFIG_SCHED_HPWORK=y
+CONFIG_SCHED_WAITPID=y
+CONFIG_SPI=y
+CONFIG_START_DAY=14
+CONFIG_STM32F7_DMA1=y
+CONFIG_STM32F7_I2S2=y
+CONFIG_STM32F7_I2S2_MCK=y
+CONFIG_STM32F7_I2S2_TX=y
+CONFIG_STM32F7_OTGFS=y
+CONFIG_STM32F7_QSPI_POLLING=y
+CONFIG_STM32F7_QUADSPI=y
+CONFIG_STM32F7_USART1=y
+CONFIG_SYSTEM_FLASH_ERASEALL=y
+CONFIG_SYSTEM_NSH=y
+CONFIG_TASK_NAME_SIZE=64
+CONFIG_USBDEV=y
+CONFIG_W25QXXXJV_QSPI_FREQUENCY=64000000
diff --git a/boards/arm/stm32f7/stm32f777zit6-meadow/include/board.h b/boards/arm/stm32f7/stm32f777zit6-meadow/include/board.h
index 9c054cd020149..85d004f8e9a5c 100644
--- a/boards/arm/stm32f7/stm32f777zit6-meadow/include/board.h
+++ b/boards/arm/stm32f7/stm32f777zit6-meadow/include/board.h
@@ -152,6 +152,13 @@
 #define STM32_RCC_PLLSAICFGR_PLLSAIQ    RCC_PLLSAICFGR_PLLSAIQ(2)
 #define STM32_RCC_PLLSAICFGR_PLLSAIR    RCC_PLLSAICFGR_PLLSAIR(2)
 
+/* SAIx input frequency = 25 / M * N / Q / P
+ *   25000000 / 25 * 384 / 2 / 8
+ */
+
+#define STM32F7_SAI1_FREQUENCY           (49142857)
+#define STM32F7_SAI2_FREQUENCY           (49142857)
+
 /* Configure Dedicated Clock Configuration Register */
 
 #define STM32_RCC_DCKCFGR1_PLLI2SDIVQ  RCC_DCKCFGR1_PLLI2SDIVQ(1)
@@ -377,6 +384,10 @@
 
 /* DMA Channel/Stream Selections ********************************************/
 
+#define DMACHAN_SAI2_A          DMAMAP_SAI2_A
+#define DMACHAN_SAI2_B          DMAMAP_SAI2_B
+#define DMACHAN_SAI1_B          DMAMAP_SAI1_B
+
 /* SDMMC */
 
 /* Stream selections are arbitrary for now but might become important in the
@@ -470,6 +481,16 @@
 #define GPIO_I2C1_SCL        (GPIO_I2C1_SCL_1|GPIO_SPEED_50MHz)
 #define GPIO_I2C1_SDA        (GPIO_I2C1_SDA_1|GPIO_SPEED_50MHz)
 
+/* I2S2 - CS4344 configuration uses I2S2 */
+
+#define GPIO_I2S2_SD      (GPIO_I2S2_SD_1  | GPIO_SPEED_100MHz)  /* PB15 */
+#define GPIO_I2S2_CK      (GPIO_I2S2_CK_3  | GPIO_SPEED_100MHz)  /* PB13 */
+#define GPIO_I2S2_WS      (GPIO_I2S2_WS_1  | GPIO_SPEED_100MHz)  /* PB12 */
+#define GPIO_I2S2_MCK     (GPIO_I2S2_MCK_0 | GPIO_SPEED_100MHz)  /* PC6 */
+
+#define DMACHAN_I2S3_RX   DMAMAP_SPI3_RX_2
+#define DMACHAN_I2S3_TX   DMAMAP_SPI3_TX_2
+
 /* QSPI Mapping  */
 
 #define GPIO_QSPI_CS  (GPIO_QUADSPI_BK1_NCS_2 | GPIO_FLOAT | GPIO_PUSHPULL | GPIO_SPEED_100MHz)
diff --git a/boards/arm/stm32f7/stm32f777zit6-meadow/src/stm32_bringup.c b/boards/arm/stm32f7/stm32f777zit6-meadow/src/stm32_bringup.c
index 7c0b50331efab..7dadf6b3d2221 100644
--- a/boards/arm/stm32f7/stm32f777zit6-meadow/src/stm32_bringup.c
+++ b/boards/arm/stm32f7/stm32f777zit6-meadow/src/stm32_bringup.c
@@ -33,6 +33,10 @@
 #include <nuttx/fs/fs.h>
 #include <nuttx/i2c/i2c_master.h>
 
+#ifdef CONFIG_AUDIO_CS4344
+#  include "stm32_cs4344.h"
+#endif
+
 #include "stm32f777zit6-meadow.h"
 
 /****************************************************************************
@@ -139,6 +143,16 @@ int stm32_bringup(void)
     }
 #endif
 
+#ifdef CONFIG_AUDIO_CS4344
+  /* Configure CS4344 audio as /dev/pcm0 on I2S2 */
+
+  ret = board_cs4344_initialize(0, 2);
+  if (ret != OK)
+    {
+      syslog(LOG_ERR, "Failed to initialize CS4344 audio: %d\n", ret);
+    }
+#endif
+
 #ifdef CONFIG_BOARD_MEADOW_F7_CORE_COMPUTE
   /* Initialize all devices in the F7 Core Compute */