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Running CRAFT for long circRNA sequences #12

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avleenc opened this issue Apr 4, 2024 · 0 comments
Open

Running CRAFT for long circRNA sequences #12

avleenc opened this issue Apr 4, 2024 · 0 comments

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@avleenc
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avleenc commented Apr 4, 2024

Hi,

I am interested in using the CRAFT tool for running functional prediction on long circRNA (3k-30k nt). The tool works perfectly fine for smaller circRNA, however it takes really long to do the same for long circRNA and the job eventually runs out of time before the prediction can be finished. I am only running miRNA prediction as I am only interested in the disease associations of these circRNA. I have tried setting high scores, however that leads to either some circRNA taking forever or some circRNA not having any miRNA output. Given the wide range of the length I am working in, I am not sure what would be the best solution here and I would really appreciate it if you could provide some input on what would be the best parameters to analyze circRNA this long.

Best Regards,
Avleen

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