diff --git a/doc/changelog.d/160.added.md b/doc/changelog.d/160.added.md
new file mode 100644
index 00000000..9521f2bc
--- /dev/null
+++ b/doc/changelog.d/160.added.md
@@ -0,0 +1 @@
+Use typeguard to check types at runtime
\ No newline at end of file
diff --git a/poetry.lock b/poetry.lock
index 578e31a4..e06621e6 100644
--- a/poetry.lock
+++ b/poetry.lock
@@ -3060,6 +3060,24 @@ files = [
 docs = ["myst-parser", "pydata-sphinx-theme", "sphinx"]
 test = ["argcomplete (>=3.0.3)", "mypy (>=1.7.0)", "pre-commit", "pytest (>=7.0,<8.2)", "pytest-mock", "pytest-mypy-testing"]
 
+[[package]]
+name = "typeguard"
+version = "4.4.1"
+description = "Run-time type checker for Python"
+optional = false
+python-versions = ">=3.9"
+files = [
+    {file = "typeguard-4.4.1-py3-none-any.whl", hash = "sha256:9324ec07a27ec67fc54a9c063020ca4c0ae6abad5e9f0f9804ca59aee68c6e21"},
+    {file = "typeguard-4.4.1.tar.gz", hash = "sha256:0d22a89d00b453b47c49875f42b6601b961757541a2e1e0ef517b6e24213c21b"},
+]
+
+[package.dependencies]
+typing-extensions = ">=4.10.0"
+
+[package.extras]
+doc = ["Sphinx (>=7)", "packaging", "sphinx-autodoc-typehints (>=1.2.0)", "sphinx-rtd-theme (>=1.3.0)"]
+test = ["coverage[toml] (>=7)", "mypy (>=1.2.0)", "pytest (>=7)"]
+
 [[package]]
 name = "typing-extensions"
 version = "4.12.2"
@@ -3152,4 +3170,4 @@ type = ["pytest-mypy"]
 [metadata]
 lock-version = "2.0"
 python-versions = ">=3.10,<4.0"
-content-hash = "eb3c7989aed9f9ebd32fe7451a03d115e0bd5983abc57147538faa2d7e7bcca8"
+content-hash = "6098f169ddd1f4fafe8660999753cbdc0e3a83b9e51ac6b42fff565f72fb8edf"
diff --git a/pyproject.toml b/pyproject.toml
index 7a45c871..4eb686aa 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -32,8 +32,8 @@ python = ">=3.10,<4.0"
 ansys-openapi-common = "^2.0.0"
 # Ensure PIP_INDEX_URL is not set in CI when reverting to a public version of the package.
 ansys-grantami-serverapi-openapi = "^4.0.0"
+typeguard = "^4.4.1"
 
-# Optional documentation dependencies
 [tool.poetry.group.doc]
 optional = true
 
diff --git a/src/ansys/grantami/jobqueue/_models.py b/src/ansys/grantami/jobqueue/_models.py
index d3cf582e..3b4d9b7a 100644
--- a/src/ansys/grantami/jobqueue/_models.py
+++ b/src/ansys/grantami/jobqueue/_models.py
@@ -32,6 +32,7 @@
 
 from ansys.grantami.serverapi_openapi import api, models
 from ansys.openapi.common import UndefinedObjectWarning, Unset
+from typeguard import typechecked
 
 
 class _DocumentedEnum(Enum):
@@ -169,6 +170,7 @@ class JobFile:
     >>> attachment_file = JobFile(pathlib.Path(r"C:\test_results\pictures\sample_001\panel_front.png"), "./assets/panel_front.png")
     """
 
+    @typechecked()
     def __init__(self, path: Union[str, pathlib.Path], virtual_path: Union[str, pathlib.Path]):
         self._path: pathlib.Path = pathlib.Path(path)
         virtual_path = pathlib.Path(virtual_path)
@@ -665,6 +667,7 @@ class ExcelExportJobRequest(JobRequest):
     <ExcelExportJobRequest: name: "Excel export job (future execution)">
     """
 
+    @typechecked()
     def __init__(
         self,
         name: str,
@@ -816,6 +819,7 @@ class ExcelImportJobRequest(ImportJobRequest):
     <ExcelImportJobRequest: name: "Excel import job (future execution)">
     """
 
+    @typechecked()
     def __init__(
         self,
         name: str,
@@ -926,6 +930,7 @@ class TextImportJobRequest(ImportJobRequest):
     <TextImportJobRequest: name: "Text import job (future execution)">
     """
 
+    @typechecked()
     def __init__(
         self,
         name: str,
diff --git a/tests/test_job_requests.py b/tests/test_job_requests.py
index a1e4fd54..ba8aa23b 100644
--- a/tests/test_job_requests.py
+++ b/tests/test_job_requests.py
@@ -24,6 +24,7 @@
 import sys
 
 import pytest
+from typeguard import TypeCheckError
 
 from ansys.grantami.jobqueue import ExcelImportJobRequest, JobFile, TextImportJobRequest
 from common import (
@@ -232,3 +233,28 @@ def test_identical_paths_raise_exception(
 def test_virtual_path_validation(virtual_path, expectation):
     with expectation:
         JobFile._validate_virtual_path(virtual_path)
+
+
+class TestInvalidArgumentTypes:
+    def test_data_file(self):
+        with pytest.raises(
+            TypeCheckError,
+            match='argument "data_files" (.*) did not match any element in the union',
+        ):
+            ExcelImportJobRequest(
+                name="Test name",
+                description=None,
+                data_files=Path("file.data"),
+            )
+
+    def test_date(self):
+        with pytest.raises(
+            TypeCheckError,
+            match='argument "scheduled_execution_date" (.*) did not match any element in the union',
+        ):
+            ExcelImportJobRequest(
+                name="Test name",
+                description=None,
+                data_files=[Path("file.data")],
+                scheduled_execution_date="2024-11-15T20:50:20+00:00",
+            )