diff --git a/ci-runners.yaml b/ci-runners.yaml
index aeb0e5ca..e5598fb1 100644
--- a/ci-runners.yaml
+++ b/ci-runners.yaml
@@ -5,11 +5,10 @@ depot-ubuntu-22.04:
   platform: linux
   free: false
 
-# TODO: Enable this runner to perform native builds for aarch64
-# depot-ubuntu-22.04-arm:
-#   arch: aarch64
-#   platform: linux
-#   free: false
+depot-ubuntu-22.04-arm:
+  arch: aarch64
+  platform: linux
+  free: false
 
 depot-macos-latest:
   arch: x86_64
diff --git a/ci-targets.yaml b/ci-targets.yaml
index cd6d2916..342998ba 100644
--- a/ci-targets.yaml
+++ b/ci-targets.yaml
@@ -50,13 +50,11 @@ linux:
       - "3.14"
     build_options:
       - debug
-      - noopt
-      - lto
+      - pgo+lto
     build_options_conditional:
       - options:
           - freethreaded+debug
-          - freethreaded+noopt
-          - freethreaded+lto
+          - freethreaded+pgo+lto
         minimum-python-version: "3.13"
 
   armv7-unknown-linux-gnueabi: