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Modification search in web version #70

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icheeseman opened this issue Aug 26, 2024 · 3 comments
Open

Modification search in web version #70

icheeseman opened this issue Aug 26, 2024 · 3 comments

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@icheeseman
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I really like pepquery and have found this to be a valuable tool. However, I would also love to be able to search for specific modifications using the web version. Is there a way to input a peptide to indicate a modification on a specific amino acid?
Thank you!

@wenbostar
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What modifications do you want to search?

@icheeseman
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I particularly want to look at protein N-termini, which means it is very useful to include acetylation (either of methionine or the second residue) as an option as most mammalian N-termini are processed and modified. Thank you!

@wenbostar
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You can add these modifications by performing the search on local. All the online MS/MS data can be accessed through PepQuery command line on your local computer: http://pepquery.org/document.html#samul

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