README.md

PLIER

Pathway-Level Information Extractor (PLIER): a generative model for gene expression data

Library dependencies

RColorBrewer
gplots
pheatmap
glmnet
rsvd
qvalue

To install the R package from github repository

library(devtools)
install_github("wgmao/PLIER")

Check out the vignette here and you can find avilable pathway dataset by calling the function ListPriors().

Reference

Mao, Weiguang, Elena Zaslavsky, Boris M. Hartmann, Stuart C. Sealfon, and Maria Chikina. "Pathway-Level Information ExtractoR (PLIER) for gene expression data." Nature Methods 16, no. 7 (2019): 607.

License

Please refer to LICENSE for details. If you are interested in using this software for a commercial purpose, please contact the developers.