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More flexible sequence weight handling #224

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thomashopf opened this issue Aug 9, 2019 · 0 comments
Open

More flexible sequence weight handling #224

thomashopf opened this issue Aug 9, 2019 · 0 comments

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@thomashopf
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Right now, sequence weights are done in a very rigid way - computed inside plmc, no option to export etc.

Ideally, we would be able to:

  • export sequence weights computed by plmc, or - even better - move the computation to a dedicated step
  • allow user-defined sequence weights or reuse existing weights
  • have more elaborate sequence weighting schemes
  • have faster sequence weighting algorithms instead of all vs all which becomes prohibitively expensive for large alignments
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