diff --git a/.github/workflows/nightly.yml b/.github/workflows/nightly.yml
new file mode 100644
index 00000000..5cecf38f
--- /dev/null
+++ b/.github/workflows/nightly.yml
@@ -0,0 +1,150 @@
+# **what?**
+# Runs unit tests and functional tests using the latest nightly DuckDB build.
+# Any tests that use community extensions are skipped because these are not released nightly.
+
+# **why?**
+# Ensure code for dbt is compatible with the bleeding edge version of DuckDB.
+
+# **when?**
+# This will run nightly, after DuckDB releases its nightly build.
+
+name: Tests and Code Checks (DuckDB nightly)
+
+on:
+  schedule:
+    - cron: '0 0 * * *' # every 24 hours, top of the hour
+  workflow_dispatch:
+
+permissions: read-all
+
+defaults:
+  run:
+    shell: bash
+
+jobs:
+  nightly:
+    name: nightly test / python ${{ matrix.python-version }}
+
+    runs-on: ubuntu-latest
+
+    strategy:
+      fail-fast: false
+      matrix:
+        python-version: ['3.9', '3.10', '3.11', '3.12']
+
+    env:
+      TOXENV: "nightly"
+      PYTEST_ADDOPTS: "-v --color=yes --csv unit_results.csv"
+
+    steps:
+      - name: Check out the repository
+        uses: actions/checkout@v4
+        with:
+          persist-credentials: false
+
+      - name: Set up Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v5
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Install python dependencies
+        run: |
+          python -m pip install tox
+          python -m pip --version
+          tox --version
+
+      - name: Run tox
+        run: tox
+
+      - name: Get current date
+        if: always()
+        id: date
+        run: echo "date=$(date +'%Y-%m-%dT%H_%M_%S')" >> $GITHUB_OUTPUT #no colons allowed for artifacts
+
+      - uses: actions/upload-artifact@v3
+        if: always()
+        with:
+          name: unit_results_${{ matrix.python-version }}-${{ steps.date.outputs.date }}.csv
+          path: unit_results.csv
+
+  build:
+    name: build packages
+
+    runs-on: ubuntu-latest
+
+    steps:
+      - name: Check out the repository
+        uses: actions/checkout@v4
+        with:
+          persist-credentials: false
+
+      - name: Set up Python
+        uses: actions/setup-python@v5
+        with:
+          python-version: '3.11'
+
+      - name: Install python dependencies
+        run: |
+          pip install --upgrade setuptools wheel twine check-wheel-contents
+          pip --version
+      - name: Build distributions
+        run: ./scripts/build-dist.sh
+
+      - name: Show distributions
+        run: ls -lh dist/
+
+      - name: Check distribution descriptions
+        run: |
+          twine check dist/*
+      - name: Check wheel contents
+        run: |
+          check-wheel-contents dist/*.whl --ignore W002,W007,W008
+
+      - uses: actions/upload-artifact@v3
+        with:
+          name: dist
+          path: dist/
+
+  test-build:
+    name: verify packages / python ${{ matrix.python-version }} / ${{ matrix.os }}
+
+    needs: build
+
+    runs-on: ${{ matrix.os }}
+
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ubuntu-latest, macos-latest, windows-latest]
+        python-version: ['3.9', '3.10', '3.11', '3.12']
+
+    steps:
+      - name: Set up Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v5
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Install python dependencies
+        run: |
+          pip install --upgrade wheel
+          pip --version
+      - uses: actions/download-artifact@v3
+        with:
+          name: dist
+          path: dist/
+
+      - name: Show distributions
+        run: ls -lh dist/
+
+      - name: Install wheel distributions
+        run: |
+          find ./dist/*.whl -maxdepth 1 -type f | xargs pip install --force-reinstall --find-links=dist/
+      - name: Check wheel distributions
+        run: |
+          dbt --version
+      - name: Install source distributions
+        run: |
+          find ./dist/*.gz -maxdepth 1 -type f | xargs pip install --force-reinstall --find-links=dist/
+      - name: Check source distributions
+        run: |
+          dbt --version
diff --git a/tests/conftest.py b/tests/conftest.py
index 0d734ae5..e1dcb912 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -83,7 +83,7 @@ def dbt_profile_target(profile_type, bv_server_process, tmpdir_factory):
             profile["token"] = os.environ.get(MOTHERDUCK_TOKEN, os.environ.get(MOTHERDUCK_TOKEN.lower()))
         profile["disable_transactions"] = True
         profile["path"] = "md:test"
-    elif profile_type == "memory":
+    elif profile_type in ["memory", "nightly"]:
         pass  # use the default path-less profile
     else:
         raise ValueError(f"Invalid profile type '{profile_type}'")
diff --git a/tests/functional/adapter/test_community_extensions.py b/tests/functional/adapter/test_community_extensions.py
index b0bebfc4..dc00135f 100644
--- a/tests/functional/adapter/test_community_extensions.py
+++ b/tests/functional/adapter/test_community_extensions.py
@@ -7,6 +7,7 @@
     run_dbt,
 )
 
+@pytest.mark.skip_profile("nightly", reason="Cannot install community extensions for nightly release")
 class BaseCommunityExtensions:
 
     @pytest.fixture(scope="class")
@@ -49,6 +50,7 @@ def test_base(self, project):
         }
         check_relation_types(project.adapter, expected)
 
+@pytest.mark.skip_profile("nightly", reason="Cannot install community extensions for nightly release")
 @pytest.mark.skip_profile("buenavista")
 class TestCommunityExtensions(BaseCommunityExtensions):
     pass
diff --git a/tests/unit/test_credentials.py b/tests/unit/test_credentials.py
index fd0756a3..191c450b 100644
--- a/tests/unit/test_credentials.py
+++ b/tests/unit/test_credentials.py
@@ -94,6 +94,7 @@ def test_add_unsupported_secret():
         assert "Secret type 'scrooge_mcduck' not found" in str(e)
 
 
+@pytest.mark.skip_profile("nightly")
 def test_add_unsupported_secret_param():
     creds = DuckDBCredentials(
         secrets=[
diff --git a/tox.ini b/tox.ini
index d87bac25..2112ca19 100644
--- a/tox.ini
+++ b/tox.ini
@@ -11,7 +11,6 @@ deps =
   -rdev-requirements.txt
   -e.
 
-
 [testenv:{functional,py38,py39,py310,py311,py312,py}]
 description = adapter functional testing
 skip_install = True
@@ -65,3 +64,15 @@ commands = {envpython} -m pytest {posargs} --profile=file tests/functional/plugi
 deps =
   -rdev-requirements.txt
   -e.
+
+[testenv:{nightly,py38,py39,py310,py311,py312,py}]
+description = duckdb nightly release testing
+skip_install = True
+passenv = *
+commands =
+  {envpython} -m pip install --upgrade --pre duckdb
+  {envpython} -m pip show duckdb
+  {envpython} -m pytest {posargs} --profile=nightly tests/unit tests/functional/adapter
+deps =
+  -rdev-requirements.txt
+  -e.