diff --git a/tests/test_yaml_manipulation.py b/tests/test_yaml_manipulation.py
index e954492..633f543 100644
--- a/tests/test_yaml_manipulation.py
+++ b/tests/test_yaml_manipulation.py
@@ -256,3 +256,32 @@ def test_whitespace_preservation_between_map_items():
 
   value: placeholder
 """)
+
+
+def test_whitespace_preservation_between_list_replacements():
+    """Test that blank lines between list items are preserved when replacing list values."""
+    s = _yml("""
+items:
+  - alice
+
+  - bob
+
+  - charlie
+""")
+    yml = _parse(s)
+
+    # Manipulate the YAML by changing the "bob" value to "BOB"
+    items_list = yml["items"]
+    for i, item in enumerate(items_list):
+        if item == "bob":
+            items_list[i] = "BOB"
+
+    # The blank lines between the list items should be preserved
+    assert yml._to_yaml() == _yml("""
+items:
+  - alice
+
+  - BOB
+
+  - charlie
+""")
diff --git a/yamlium/nodes.py b/yamlium/nodes.py
index 00a0f5b..9122a85 100644
--- a/yamlium/nodes.py
+++ b/yamlium/nodes.py
@@ -25,6 +25,15 @@ def _convert_type(obj: dict | list | str, /) -> Node:
     return Scalar(_value=obj)
 
 
+def _preserve_metadata(old_value: Node | None, new_value: Node) -> Node:
+    """Copy metadata (newlines, comments) from old value to new value."""
+    if old_value is not None and isinstance(old_value, Node):
+        new_value.newlines = old_value.newlines
+        new_value.inline_comments = old_value.inline_comments
+        new_value.stand_alone_comments = old_value.stand_alone_comments
+    return new_value
+
+
 class StrManipulator:
     """This class allows string manipulation."""
 
@@ -432,7 +441,10 @@ def append(self, item: Any) -> None:
         super().append(_convert_type(item))
 
     def __setitem__(self, i: int, value: Any) -> None:
-        super().__setitem__(i, _convert_type(value))
+        """Set an item in the sequence."""
+        old_value = self[i] if i < len(self) else None
+        new_value = _preserve_metadata(old_value, _convert_type(value))
+        super().__setitem__(i, new_value)
 
     def extend(self, items: list) -> None:
         """Extend the sequence with multiple items.
@@ -501,23 +513,12 @@ def _to_yaml(self, i: int = 0) -> str:
         return result
 
     def __setitem__(self, key: Key | str, value: Any) -> None:
-        """Set a key-value pair in the mapping.
-
-        Args:
-            key: The key to set. Can be a Key Any or string.
-            value: The value to set. Will be converted to a Node if it isn't one.
-        """
+        """Set a key-value pair in the mapping."""
         if isinstance(key, str):
             key = Key(_value=key)
 
-        # Preserve newlines and comments from old value if it exists
         old_value = self.get(key)
-        new_value = _convert_type(value)
-        if old_value is not None and isinstance(old_value, Node):
-            new_value.newlines = old_value.newlines
-            new_value.inline_comments = old_value.inline_comments
-            new_value.stand_alone_comments = old_value.stand_alone_comments
-
+        new_value = _preserve_metadata(old_value, _convert_type(value))
         super().__setitem__(key, new_value)
 
     def update(self, other: dict) -> None: