Steam log: "[Proton] prefix has an invalid version"

[rugk]

I see this in the log:

Caching cursor image for default, size 48x48, serial 100, cache size = 0
Proton: Upgrading prefix from GE-Proton10-17 to GE-Proton10-32 (/var/home/rugk/.var/app/com.valvesoftware.Steam/.local/share/Steam/steamapps/compatdata/0/)
Proton: Prefix has an invalid version?! You may want to back up user files and delete this prefix.
sh: Zeile 1: lsb_release: Kommando nicht gefunden
sh: Zeile 1: lsb_release: Kommando nicht gefunden
ProtonFixes[1389] WARN: Skipping fix execution. We are probably running a unit test.
fsync: up and running.

I see this again and again, is this problematic and what can one do about that?