diff --git a/nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.ipynb b/nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.ipynb
index 5f63a11c..b785acc8 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.ipynb
+++ b/nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.ipynb
@@ -5,10 +5,10 @@
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@@ -22,10 +22,10 @@
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@@ -42,10 +42,10 @@
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@@ -60,16 +60,16 @@
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@@ -91,10 +91,10 @@
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@@ -109,16 +109,16 @@
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@@ -134,16 +134,16 @@
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@@ -162,20 +162,20 @@
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@@ -200,20 +200,20 @@
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@@ -228,10 +228,10 @@
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@@ -242,20 +242,20 @@
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@@ -280,20 +280,20 @@
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@@ -320,10 +320,10 @@
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@@ -334,20 +334,45 @@
   },
   {
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-   "execution_count": 7,
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+     "iopub.execute_input": "2023-09-07T01:00:39.903380Z",
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+     "start_time": "2023-09-07T01:00:39.901618",
+     "status": "completed"
+    },
+    "tags": []
+   },
+   "outputs": [],
+   "source": [
+    "tissue_in_file_names = [f\"_data_{simplify_string(t.lower())}-\" for t in TISSUES]"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 9,
+   "id": "cd78a8c5",
+   "metadata": {
+    "execution": {
+     "iopub.execute_input": "2023-09-07T01:00:39.908339Z",
+     "iopub.status.busy": "2023-09-07T01:00:39.908201Z",
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@@ -356,7 +381,7 @@
     {
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-       "54"
+       "1"
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@@ -365,29 +390,13 @@
     {
      "data": {
       "text/plain": [
-       "[PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_subcutaneous-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_visceral_omentum-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adrenal_gland-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_artery_aorta-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_artery_coronary-var_pc_log2.pkl')]"
+       "[PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_whole_blood-var_pc_log2.pkl')]"
       ]
      },
      "metadata": {},
      "output_type": "display_data"
     }
    ],
-   "source": [
-    "tissue_in_file_names = [f\"_data_{simplify_string(t.lower())}-\" for t in TISSUES]"
-   ]
-  },
-  {
-   "cell_type": "code",
-   "execution_count": null,
-   "id": "cd78a8c5",
-   "metadata": {
-    "tags": []
-   },
-   "outputs": [],
    "source": [
     "input_files = sorted(list(INPUT_DIR.glob(f\"*-{GENE_SELECTION_STRATEGY}.pkl\")))\n",
     "input_files = [\n",
@@ -404,10 +413,10 @@
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@@ -421,10 +430,10 @@
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@@ -435,20 +444,20 @@
   },
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-   "execution_count": 8,
+   "execution_count": 10,
    "id": "5dd40707-759f-4bf9-b8cc-84811b2dfe53",
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-     "shell.execute_reply": "2022-01-21T05:24:20.927945Z"
+     "iopub.execute_input": "2023-09-07T01:00:39.920791Z",
+     "iopub.status.busy": "2023-09-07T01:00:39.920650Z",
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      "exception": false,
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@@ -457,7 +466,7 @@
     {
      "data": {
       "text/plain": [
-       "PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_subcutaneous-var_pc_log2.pkl')"
+       "PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_whole_blood-var_pc_log2.pkl')"
       ]
      },
      "metadata": {},
@@ -471,20 +480,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 9,
+   "execution_count": 11,
    "id": "e8acd036-93f7-46c0-a1ee-8da0c2c24790",
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-     "shell.execute_reply": "2022-01-21T05:24:20.966363Z"
+     "iopub.execute_input": "2023-09-07T01:00:39.934555Z",
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      "status": "completed"
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     "tags": []
@@ -493,10 +502,10 @@
     {
      "data": {
       "text/plain": [
-       "(500, 663)"
+       "(500, 755)"
       ]
      },
-     "execution_count": 9,
+     "execution_count": 11,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -507,20 +516,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 10,
+   "execution_count": 12,
    "id": "111e360b-dbe4-4b69-9029-7b7669eb5ddc",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:24:21.004121Z",
-     "iopub.status.busy": "2022-01-21T05:24:21.003631Z",
-     "iopub.status.idle": "2022-01-21T05:24:21.022339Z",
-     "shell.execute_reply": "2022-01-21T05:24:21.021901Z"
+     "iopub.execute_input": "2023-09-07T01:00:39.939756Z",
+     "iopub.status.busy": "2023-09-07T01:00:39.939686Z",
+     "iopub.status.idle": "2023-09-07T01:00:39.950161Z",
+     "shell.execute_reply": "2023-09-07T01:00:39.949953Z"
     },
     "papermill": {
-     "duration": 0.039109,
-     "end_time": "2022-01-21T05:24:21.022431",
+     "duration": 0.012763,
+     "end_time": "2023-09-07T01:00:39.950777",
      "exception": false,
-     "start_time": "2022-01-21T05:24:20.983322",
+     "start_time": "2023-09-07T01:00:39.938014",
      "status": "completed"
     },
     "tags": []
@@ -547,27 +556,27 @@
        "  <thead>\n",
        "    <tr style=\"text-align: right;\">\n",
        "      <th></th>\n",
-       "      <th>GTEX-1117F-0226-SM-5GZZ7</th>\n",
-       "      <th>GTEX-111CU-1826-SM-5GZYN</th>\n",
-       "      <th>GTEX-111FC-0226-SM-5N9B8</th>\n",
-       "      <th>GTEX-111VG-2326-SM-5N9BK</th>\n",
-       "      <th>GTEX-111YS-2426-SM-5GZZQ</th>\n",
-       "      <th>GTEX-1122O-2026-SM-9YFMG</th>\n",
-       "      <th>GTEX-1128S-2126-SM-5H12U</th>\n",
-       "      <th>GTEX-113IC-0226-SM-5HL5C</th>\n",
-       "      <th>GTEX-117YX-2226-SM-5EGJJ</th>\n",
-       "      <th>GTEX-11DXW-0326-SM-5H11W</th>\n",
+       "      <th>GTEX-111YS-0006-SM-5NQBE</th>\n",
+       "      <th>GTEX-1122O-0005-SM-5O99J</th>\n",
+       "      <th>GTEX-1128S-0005-SM-5P9HI</th>\n",
+       "      <th>GTEX-113IC-0006-SM-5NQ9C</th>\n",
+       "      <th>GTEX-113JC-0006-SM-5O997</th>\n",
+       "      <th>GTEX-117XS-0005-SM-5PNU6</th>\n",
+       "      <th>GTEX-117YW-0005-SM-5NQ8Z</th>\n",
+       "      <th>GTEX-1192W-0005-SM-5NQBQ</th>\n",
+       "      <th>GTEX-1192X-0005-SM-5NQC3</th>\n",
+       "      <th>GTEX-11DXW-0006-SM-5NQ7Y</th>\n",
        "      <th>...</th>\n",
-       "      <th>GTEX-ZXES-2026-SM-5NQ6R</th>\n",
-       "      <th>GTEX-ZXG5-0226-SM-59HJI</th>\n",
-       "      <th>GTEX-ZYFC-0326-SM-5NQ7H</th>\n",
-       "      <th>GTEX-ZYFD-0226-SM-5NQ86</th>\n",
-       "      <th>GTEX-ZYT6-0326-SM-7LG5R</th>\n",
-       "      <th>GTEX-ZYVF-0226-SM-5GIEG</th>\n",
-       "      <th>GTEX-ZYW4-0226-SM-5E44M</th>\n",
-       "      <th>GTEX-ZYY3-0226-SM-5E45M</th>\n",
-       "      <th>GTEX-ZZ64-1626-SM-5E43W</th>\n",
-       "      <th>GTEX-ZZPU-2726-SM-5NQ8O</th>\n",
+       "      <th>GTEX-ZVE2-0006-SM-51MRW</th>\n",
+       "      <th>GTEX-ZVP2-0005-SM-51MRK</th>\n",
+       "      <th>GTEX-ZVT2-0005-SM-57WBW</th>\n",
+       "      <th>GTEX-ZVT3-0006-SM-51MT9</th>\n",
+       "      <th>GTEX-ZVT4-0006-SM-57WB8</th>\n",
+       "      <th>GTEX-ZVTK-0006-SM-57WBK</th>\n",
+       "      <th>GTEX-ZVZP-0006-SM-51MSW</th>\n",
+       "      <th>GTEX-ZVZQ-0006-SM-51MR8</th>\n",
+       "      <th>GTEX-ZXES-0005-SM-57WCB</th>\n",
+       "      <th>GTEX-ZXG5-0005-SM-57WCN</th>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>gene_ens_id</th>\n",
@@ -596,215 +605,215 @@
        "  </thead>\n",
        "  <tbody>\n",
        "    <tr>\n",
-       "      <th>ENSG00000129824.15</th>\n",
-       "      <td>0.9301</td>\n",
-       "      <td>270.4000</td>\n",
-       "      <td>345.8000</td>\n",
-       "      <td>242.20</td>\n",
-       "      <td>180.800</td>\n",
-       "      <td>0.1904</td>\n",
-       "      <td>0.18640</td>\n",
-       "      <td>294.40</td>\n",
-       "      <td>332.6000</td>\n",
-       "      <td>216.0000</td>\n",
+       "      <th>ENSG00000169429.10</th>\n",
+       "      <td>0.5623</td>\n",
+       "      <td>0.8067</td>\n",
+       "      <td>116.90000</td>\n",
+       "      <td>4.047</td>\n",
+       "      <td>211.0</td>\n",
+       "      <td>58.110</td>\n",
+       "      <td>68.38</td>\n",
+       "      <td>249.50</td>\n",
+       "      <td>5.095</td>\n",
+       "      <td>295.9</td>\n",
        "      <td>...</td>\n",
-       "      <td>0.2916</td>\n",
-       "      <td>311.700</td>\n",
-       "      <td>230.0000</td>\n",
-       "      <td>302.20000</td>\n",
-       "      <td>316.500</td>\n",
-       "      <td>0.2567</td>\n",
-       "      <td>340.2000</td>\n",
-       "      <td>0.6962</td>\n",
-       "      <td>269.1000</td>\n",
-       "      <td>0.1917</td>\n",
+       "      <td>39.960</td>\n",
+       "      <td>0.1393</td>\n",
+       "      <td>0.22380</td>\n",
+       "      <td>245.0</td>\n",
+       "      <td>513.6</td>\n",
+       "      <td>1626.00</td>\n",
+       "      <td>0.5633</td>\n",
+       "      <td>515.70</td>\n",
+       "      <td>1.19400</td>\n",
+       "      <td>1163.00</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <td>100.4000</td>\n",
-       "      <td>785.1000</td>\n",
-       "      <td>14.0000</td>\n",
-       "      <td>44.48</td>\n",
-       "      <td>17.960</td>\n",
-       "      <td>2.5670</td>\n",
-       "      <td>0.18410</td>\n",
-       "      <td>46.91</td>\n",
-       "      <td>13.9500</td>\n",
-       "      <td>0.1953</td>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <td>0.6529</td>\n",
+       "      <td>1.3850</td>\n",
+       "      <td>199.20000</td>\n",
+       "      <td>2.266</td>\n",
+       "      <td>116.7</td>\n",
+       "      <td>192.300</td>\n",
+       "      <td>161.50</td>\n",
+       "      <td>263.50</td>\n",
+       "      <td>23.540</td>\n",
+       "      <td>251.9</td>\n",
        "      <td>...</td>\n",
-       "      <td>3.9480</td>\n",
-       "      <td>108.800</td>\n",
-       "      <td>3.8230</td>\n",
-       "      <td>6.61700</td>\n",
-       "      <td>11.440</td>\n",
-       "      <td>7.6190</td>\n",
-       "      <td>27.4300</td>\n",
-       "      <td>21.0200</td>\n",
-       "      <td>122.6000</td>\n",
-       "      <td>10.8200</td>\n",
+       "      <td>114.300</td>\n",
+       "      <td>1.8330</td>\n",
+       "      <td>0.41150</td>\n",
+       "      <td>149.0</td>\n",
+       "      <td>935.3</td>\n",
+       "      <td>233.60</td>\n",
+       "      <td>0.8882</td>\n",
+       "      <td>134.00</td>\n",
+       "      <td>1.12000</td>\n",
+       "      <td>295.70</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000134184.12</th>\n",
-       "      <td>75.6800</td>\n",
-       "      <td>0.2281</td>\n",
-       "      <td>0.2070</td>\n",
-       "      <td>0.00</td>\n",
-       "      <td>36.930</td>\n",
-       "      <td>0.1651</td>\n",
-       "      <td>0.06058</td>\n",
-       "      <td>174.00</td>\n",
-       "      <td>0.1429</td>\n",
-       "      <td>56.4700</td>\n",
+       "      <th>ENSG00000163631.16</th>\n",
+       "      <td>1.8480</td>\n",
+       "      <td>0.2503</td>\n",
+       "      <td>0.08429</td>\n",
+       "      <td>1.251</td>\n",
+       "      <td>1348.0</td>\n",
+       "      <td>9.971</td>\n",
+       "      <td>101.30</td>\n",
+       "      <td>95.09</td>\n",
+       "      <td>1.264</td>\n",
+       "      <td>119.3</td>\n",
        "      <td>...</td>\n",
-       "      <td>54.9200</td>\n",
-       "      <td>46.230</td>\n",
-       "      <td>0.1468</td>\n",
-       "      <td>0.04705</td>\n",
-       "      <td>67.240</td>\n",
-       "      <td>0.4005</td>\n",
-       "      <td>0.5507</td>\n",
-       "      <td>56.0600</td>\n",
-       "      <td>0.4048</td>\n",
-       "      <td>0.0000</td>\n",
+       "      <td>2.092</td>\n",
+       "      <td>2.1100</td>\n",
+       "      <td>0.03588</td>\n",
+       "      <td>171.8</td>\n",
+       "      <td>107.1</td>\n",
+       "      <td>71.25</td>\n",
+       "      <td>1.7720</td>\n",
+       "      <td>309.60</td>\n",
+       "      <td>0.07361</td>\n",
+       "      <td>17.75</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000224114.1</th>\n",
-       "      <td>1.1500</td>\n",
-       "      <td>0.8068</td>\n",
-       "      <td>0.5856</td>\n",
-       "      <td>74.28</td>\n",
-       "      <td>0.314</td>\n",
-       "      <td>0.6115</td>\n",
-       "      <td>49.95000</td>\n",
-       "      <td>139.60</td>\n",
-       "      <td>83.5400</td>\n",
-       "      <td>1.3640</td>\n",
+       "      <th>ENSG00000277632.1</th>\n",
+       "      <td>1.6960</td>\n",
+       "      <td>1.3450</td>\n",
+       "      <td>235.10000</td>\n",
+       "      <td>11.770</td>\n",
+       "      <td>141.7</td>\n",
+       "      <td>199.100</td>\n",
+       "      <td>525.50</td>\n",
+       "      <td>659.90</td>\n",
+       "      <td>10.910</td>\n",
+       "      <td>209.3</td>\n",
        "      <td>...</td>\n",
-       "      <td>0.1915</td>\n",
-       "      <td>5.593</td>\n",
-       "      <td>60.0200</td>\n",
-       "      <td>61.04000</td>\n",
-       "      <td>1.596</td>\n",
-       "      <td>81.6000</td>\n",
-       "      <td>149.4000</td>\n",
-       "      <td>0.2032</td>\n",
-       "      <td>1.2270</td>\n",
-       "      <td>0.5036</td>\n",
+       "      <td>61.340</td>\n",
+       "      <td>2.2500</td>\n",
+       "      <td>0.72310</td>\n",
+       "      <td>261.2</td>\n",
+       "      <td>400.0</td>\n",
+       "      <td>288.50</td>\n",
+       "      <td>2.6960</td>\n",
+       "      <td>287.50</td>\n",
+       "      <td>3.32300</td>\n",
+       "      <td>618.90</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000173432.10</th>\n",
-       "      <td>2765.0000</td>\n",
-       "      <td>241.1000</td>\n",
-       "      <td>1.5220</td>\n",
-       "      <td>99.98</td>\n",
-       "      <td>921.400</td>\n",
-       "      <td>2859.0000</td>\n",
-       "      <td>3874.00000</td>\n",
-       "      <td>21.41</td>\n",
-       "      <td>1338.0000</td>\n",
-       "      <td>61.4800</td>\n",
+       "      <th>ENSG00000239839.6</th>\n",
+       "      <td>185.2000</td>\n",
+       "      <td>1.7790</td>\n",
+       "      <td>694.30000</td>\n",
+       "      <td>23.840</td>\n",
+       "      <td>297.3</td>\n",
+       "      <td>3122.000</td>\n",
+       "      <td>2521.00</td>\n",
+       "      <td>1504.00</td>\n",
+       "      <td>80.060</td>\n",
+       "      <td>652.0</td>\n",
        "      <td>...</td>\n",
-       "      <td>1666.0000</td>\n",
-       "      <td>165.300</td>\n",
-       "      <td>81.9700</td>\n",
-       "      <td>180.90000</td>\n",
-       "      <td>24.650</td>\n",
-       "      <td>276.2000</td>\n",
-       "      <td>53.5400</td>\n",
-       "      <td>1436.0000</td>\n",
-       "      <td>140.5000</td>\n",
-       "      <td>756.3000</td>\n",
+       "      <td>1010.000</td>\n",
+       "      <td>253.8000</td>\n",
+       "      <td>94.52000</td>\n",
+       "      <td>6083.0</td>\n",
+       "      <td>2768.0</td>\n",
+       "      <td>52.06</td>\n",
+       "      <td>34.5700</td>\n",
+       "      <td>17.36</td>\n",
+       "      <td>352.30000</td>\n",
+       "      <td>63.85</td>\n",
        "    </tr>\n",
        "  </tbody>\n",
        "</table>\n",
-       "<p>5 rows × 663 columns</p>\n",
+       "<p>5 rows × 755 columns</p>\n",
        "</div>"
       ],
       "text/plain": [
-       "                    GTEX-1117F-0226-SM-5GZZ7  GTEX-111CU-1826-SM-5GZYN  \\\n",
+       "                    GTEX-111YS-0006-SM-5NQBE  GTEX-1122O-0005-SM-5O99J  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                    0.9301                  270.4000   \n",
-       "ENSG00000149968.11                  100.4000                  785.1000   \n",
-       "ENSG00000134184.12                   75.6800                    0.2281   \n",
-       "ENSG00000224114.1                     1.1500                    0.8068   \n",
-       "ENSG00000173432.10                 2765.0000                  241.1000   \n",
+       "ENSG00000169429.10                    0.5623                    0.8067   \n",
+       "ENSG00000135245.9                     0.6529                    1.3850   \n",
+       "ENSG00000163631.16                    1.8480                    0.2503   \n",
+       "ENSG00000277632.1                     1.6960                    1.3450   \n",
+       "ENSG00000239839.6                   185.2000                    1.7790   \n",
        "\n",
-       "                    GTEX-111FC-0226-SM-5N9B8  GTEX-111VG-2326-SM-5N9BK  \\\n",
+       "                    GTEX-1128S-0005-SM-5P9HI  GTEX-113IC-0006-SM-5NQ9C  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                  345.8000                    242.20   \n",
-       "ENSG00000149968.11                   14.0000                     44.48   \n",
-       "ENSG00000134184.12                    0.2070                      0.00   \n",
-       "ENSG00000224114.1                     0.5856                     74.28   \n",
-       "ENSG00000173432.10                    1.5220                     99.98   \n",
+       "ENSG00000169429.10                 116.90000                     4.047   \n",
+       "ENSG00000135245.9                  199.20000                     2.266   \n",
+       "ENSG00000163631.16                   0.08429                     1.251   \n",
+       "ENSG00000277632.1                  235.10000                    11.770   \n",
+       "ENSG00000239839.6                  694.30000                    23.840   \n",
        "\n",
-       "                    GTEX-111YS-2426-SM-5GZZQ  GTEX-1122O-2026-SM-9YFMG  \\\n",
+       "                    GTEX-113JC-0006-SM-5O997  GTEX-117XS-0005-SM-5PNU6  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                   180.800                    0.1904   \n",
-       "ENSG00000149968.11                    17.960                    2.5670   \n",
-       "ENSG00000134184.12                    36.930                    0.1651   \n",
-       "ENSG00000224114.1                      0.314                    0.6115   \n",
-       "ENSG00000173432.10                   921.400                 2859.0000   \n",
+       "ENSG00000169429.10                     211.0                    58.110   \n",
+       "ENSG00000135245.9                      116.7                   192.300   \n",
+       "ENSG00000163631.16                    1348.0                     9.971   \n",
+       "ENSG00000277632.1                      141.7                   199.100   \n",
+       "ENSG00000239839.6                      297.3                  3122.000   \n",
        "\n",
-       "                    GTEX-1128S-2126-SM-5H12U  GTEX-113IC-0226-SM-5HL5C  \\\n",
+       "                    GTEX-117YW-0005-SM-5NQ8Z  GTEX-1192W-0005-SM-5NQBQ  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                   0.18640                    294.40   \n",
-       "ENSG00000149968.11                   0.18410                     46.91   \n",
-       "ENSG00000134184.12                   0.06058                    174.00   \n",
-       "ENSG00000224114.1                   49.95000                    139.60   \n",
-       "ENSG00000173432.10                3874.00000                     21.41   \n",
+       "ENSG00000169429.10                     68.38                    249.50   \n",
+       "ENSG00000135245.9                     161.50                    263.50   \n",
+       "ENSG00000163631.16                    101.30                     95.09   \n",
+       "ENSG00000277632.1                     525.50                    659.90   \n",
+       "ENSG00000239839.6                    2521.00                   1504.00   \n",
        "\n",
-       "                    GTEX-117YX-2226-SM-5EGJJ  GTEX-11DXW-0326-SM-5H11W  ...  \\\n",
+       "                    GTEX-1192X-0005-SM-5NQC3  GTEX-11DXW-0006-SM-5NQ7Y  ...  \\\n",
        "gene_ens_id                                                             ...   \n",
-       "ENSG00000129824.15                  332.6000                  216.0000  ...   \n",
-       "ENSG00000149968.11                   13.9500                    0.1953  ...   \n",
-       "ENSG00000134184.12                    0.1429                   56.4700  ...   \n",
-       "ENSG00000224114.1                    83.5400                    1.3640  ...   \n",
-       "ENSG00000173432.10                 1338.0000                   61.4800  ...   \n",
+       "ENSG00000169429.10                     5.095                     295.9  ...   \n",
+       "ENSG00000135245.9                     23.540                     251.9  ...   \n",
+       "ENSG00000163631.16                     1.264                     119.3  ...   \n",
+       "ENSG00000277632.1                     10.910                     209.3  ...   \n",
+       "ENSG00000239839.6                     80.060                     652.0  ...   \n",
        "\n",
-       "                    GTEX-ZXES-2026-SM-5NQ6R  GTEX-ZXG5-0226-SM-59HJI  \\\n",
+       "                    GTEX-ZVE2-0006-SM-51MRW  GTEX-ZVP2-0005-SM-51MRK  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                   0.2916                  311.700   \n",
-       "ENSG00000149968.11                   3.9480                  108.800   \n",
-       "ENSG00000134184.12                  54.9200                   46.230   \n",
-       "ENSG00000224114.1                    0.1915                    5.593   \n",
-       "ENSG00000173432.10                1666.0000                  165.300   \n",
+       "ENSG00000169429.10                   39.960                   0.1393   \n",
+       "ENSG00000135245.9                   114.300                   1.8330   \n",
+       "ENSG00000163631.16                    2.092                   2.1100   \n",
+       "ENSG00000277632.1                    61.340                   2.2500   \n",
+       "ENSG00000239839.6                  1010.000                 253.8000   \n",
        "\n",
-       "                    GTEX-ZYFC-0326-SM-5NQ7H  GTEX-ZYFD-0226-SM-5NQ86  \\\n",
+       "                    GTEX-ZVT2-0005-SM-57WBW  GTEX-ZVT3-0006-SM-51MT9  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                 230.0000                302.20000   \n",
-       "ENSG00000149968.11                   3.8230                  6.61700   \n",
-       "ENSG00000134184.12                   0.1468                  0.04705   \n",
-       "ENSG00000224114.1                   60.0200                 61.04000   \n",
-       "ENSG00000173432.10                  81.9700                180.90000   \n",
+       "ENSG00000169429.10                  0.22380                    245.0   \n",
+       "ENSG00000135245.9                   0.41150                    149.0   \n",
+       "ENSG00000163631.16                  0.03588                    171.8   \n",
+       "ENSG00000277632.1                   0.72310                    261.2   \n",
+       "ENSG00000239839.6                  94.52000                   6083.0   \n",
        "\n",
-       "                    GTEX-ZYT6-0326-SM-7LG5R  GTEX-ZYVF-0226-SM-5GIEG  \\\n",
+       "                    GTEX-ZVT4-0006-SM-57WB8  GTEX-ZVTK-0006-SM-57WBK  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                  316.500                   0.2567   \n",
-       "ENSG00000149968.11                   11.440                   7.6190   \n",
-       "ENSG00000134184.12                   67.240                   0.4005   \n",
-       "ENSG00000224114.1                     1.596                  81.6000   \n",
-       "ENSG00000173432.10                   24.650                 276.2000   \n",
+       "ENSG00000169429.10                    513.6                  1626.00   \n",
+       "ENSG00000135245.9                     935.3                   233.60   \n",
+       "ENSG00000163631.16                    107.1                    71.25   \n",
+       "ENSG00000277632.1                     400.0                   288.50   \n",
+       "ENSG00000239839.6                    2768.0                    52.06   \n",
        "\n",
-       "                    GTEX-ZYW4-0226-SM-5E44M  GTEX-ZYY3-0226-SM-5E45M  \\\n",
+       "                    GTEX-ZVZP-0006-SM-51MSW  GTEX-ZVZQ-0006-SM-51MR8  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                 340.2000                   0.6962   \n",
-       "ENSG00000149968.11                  27.4300                  21.0200   \n",
-       "ENSG00000134184.12                   0.5507                  56.0600   \n",
-       "ENSG00000224114.1                  149.4000                   0.2032   \n",
-       "ENSG00000173432.10                  53.5400                1436.0000   \n",
+       "ENSG00000169429.10                   0.5633                   515.70   \n",
+       "ENSG00000135245.9                    0.8882                   134.00   \n",
+       "ENSG00000163631.16                   1.7720                   309.60   \n",
+       "ENSG00000277632.1                    2.6960                   287.50   \n",
+       "ENSG00000239839.6                   34.5700                    17.36   \n",
        "\n",
-       "                    GTEX-ZZ64-1626-SM-5E43W  GTEX-ZZPU-2726-SM-5NQ8O  \n",
+       "                    GTEX-ZXES-0005-SM-57WCB  GTEX-ZXG5-0005-SM-57WCN  \n",
        "gene_ens_id                                                           \n",
-       "ENSG00000129824.15                 269.1000                   0.1917  \n",
-       "ENSG00000149968.11                 122.6000                  10.8200  \n",
-       "ENSG00000134184.12                   0.4048                   0.0000  \n",
-       "ENSG00000224114.1                    1.2270                   0.5036  \n",
-       "ENSG00000173432.10                 140.5000                 756.3000  \n",
+       "ENSG00000169429.10                  1.19400                  1163.00  \n",
+       "ENSG00000135245.9                   1.12000                   295.70  \n",
+       "ENSG00000163631.16                  0.07361                    17.75  \n",
+       "ENSG00000277632.1                   3.32300                   618.90  \n",
+       "ENSG00000239839.6                 352.30000                    63.85  \n",
        "\n",
-       "[5 rows x 663 columns]"
+       "[5 rows x 755 columns]"
       ]
      },
-     "execution_count": 10,
+     "execution_count": 12,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -818,10 +827,10 @@
    "id": "5903f3f5-791e-4f03-9d79-600102933d04",
    "metadata": {
     "papermill": {
-     "duration": 0.016529,
-     "end_time": "2022-01-21T05:24:21.055833",
+     "duration": 0.002391,
+     "end_time": "2023-09-07T01:00:39.955456",
      "exception": false,
-     "start_time": "2022-01-21T05:24:21.039304",
+     "start_time": "2023-09-07T01:00:39.953065",
      "status": "completed"
     },
     "tags": []
@@ -832,20 +841,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 11,
+   "execution_count": 13,
    "id": "118a6631-1cfd-44a3-bd85-5ec7118edd03",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:24:21.092981Z",
-     "iopub.status.busy": "2022-01-21T05:24:21.092471Z",
-     "iopub.status.idle": "2022-01-21T05:24:21.099815Z",
-     "shell.execute_reply": "2022-01-21T05:24:21.099429Z"
+     "iopub.execute_input": "2023-09-07T01:00:39.961934Z",
+     "iopub.status.busy": "2023-09-07T01:00:39.961759Z",
+     "iopub.status.idle": "2023-09-07T01:00:39.965952Z",
+     "shell.execute_reply": "2023-09-07T01:00:39.965776Z"
     },
     "papermill": {
-     "duration": 0.027831,
-     "end_time": "2022-01-21T05:24:21.099943",
+     "duration": 0.008039,
+     "end_time": "2023-09-07T01:00:39.966715",
      "exception": false,
-     "start_time": "2022-01-21T05:24:21.072112",
+     "start_time": "2023-09-07T01:00:39.958676",
      "status": "completed"
     },
     "tags": []
@@ -881,9 +890,9 @@
        "  <thead>\n",
        "    <tr style=\"text-align: right;\">\n",
        "      <th>gene_ens_id</th>\n",
-       "      <th>ENSG00000129824.15</th>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <th>ENSG00000134184.12</th>\n",
+       "      <th>ENSG00000169429.10</th>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <th>ENSG00000163631.16</th>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>gene_ens_id</th>\n",
@@ -894,21 +903,21 @@
        "  </thead>\n",
        "  <tbody>\n",
        "    <tr>\n",
-       "      <th>ENSG00000129824.15</th>\n",
+       "      <th>ENSG00000169429.10</th>\n",
        "      <td>1.000000</td>\n",
-       "      <td>0.142708</td>\n",
-       "      <td>0.044838</td>\n",
+       "      <td>0.571672</td>\n",
+       "      <td>0.126906</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <td>0.142708</td>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <td>0.571672</td>\n",
        "      <td>1.000000</td>\n",
-       "      <td>-0.007867</td>\n",
+       "      <td>0.110612</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000134184.12</th>\n",
-       "      <td>0.044838</td>\n",
-       "      <td>-0.007867</td>\n",
+       "      <th>ENSG00000163631.16</th>\n",
+       "      <td>0.126906</td>\n",
+       "      <td>0.110612</td>\n",
        "      <td>1.000000</td>\n",
        "    </tr>\n",
        "  </tbody>\n",
@@ -916,11 +925,11 @@
        "</div>"
       ],
       "text/plain": [
-       "gene_ens_id         ENSG00000129824.15  ENSG00000149968.11  ENSG00000134184.12\n",
-       "gene_ens_id                                                                   \n",
-       "ENSG00000129824.15            1.000000            0.142708            0.044838\n",
-       "ENSG00000149968.11            0.142708            1.000000           -0.007867\n",
-       "ENSG00000134184.12            0.044838           -0.007867            1.000000"
+       "gene_ens_id         ENSG00000169429.10  ENSG00000135245.9  ENSG00000163631.16\n",
+       "gene_ens_id                                                                  \n",
+       "ENSG00000169429.10            1.000000           0.571672            0.126906\n",
+       "ENSG00000135245.9             0.571672           1.000000            0.110612\n",
+       "ENSG00000163631.16            0.126906           0.110612            1.000000"
       ]
      },
      "metadata": {},
@@ -936,20 +945,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 12,
+   "execution_count": 14,
    "id": "d32281d8-f640-4f87-a1d5-aefa0757e9c3",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:24:21.139463Z",
-     "iopub.status.busy": "2022-01-21T05:24:21.139009Z",
-     "iopub.status.idle": "2022-01-21T05:24:25.078285Z",
-     "shell.execute_reply": "2022-01-21T05:24:25.078692Z"
+     "iopub.execute_input": "2023-09-07T01:00:39.971181Z",
+     "iopub.status.busy": "2023-09-07T01:00:39.971078Z",
+     "iopub.status.idle": "2023-09-07T01:00:43.582088Z",
+     "shell.execute_reply": "2023-09-07T01:00:43.581900Z"
     },
     "papermill": {
-     "duration": 3.960722,
-     "end_time": "2022-01-21T05:24:25.078804",
+     "duration": 3.613767,
+     "end_time": "2023-09-07T01:00:43.582758",
      "exception": false,
-     "start_time": "2022-01-21T05:24:21.118082",
+     "start_time": "2023-09-07T01:00:39.968991",
      "status": "completed"
     },
     "tags": []
@@ -959,7 +968,7 @@
      "name": "stdout",
      "output_type": "stream",
      "text": [
-      "48.6 ms ± 50.1 µs per loop (mean ± std. dev. of 7 runs, 10 loops each)\n"
+      "17.1 ms ± 0 ns per loop (mean ± std. dev. of 1 run, 100 loops each)\n"
      ]
     }
    ],
@@ -972,10 +981,10 @@
    "id": "fc2f7184-c0da-438c-94f5-002912793636",
    "metadata": {
     "papermill": {
-     "duration": 0.017101,
-     "end_time": "2022-01-21T05:24:25.128197",
+     "duration": 0.001782,
+     "end_time": "2023-09-07T01:00:43.586424",
      "exception": false,
-     "start_time": "2022-01-21T05:24:25.111096",
+     "start_time": "2023-09-07T01:00:43.584642",
      "status": "completed"
     },
     "tags": []
@@ -986,20 +995,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 13,
+   "execution_count": 15,
    "id": "1237ae45-d4fc-4074-bfc7-a1de75aeea48",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:24:25.168030Z",
-     "iopub.status.busy": "2022-01-21T05:24:25.167536Z",
-     "iopub.status.idle": "2022-01-21T05:27:00.176803Z",
-     "shell.execute_reply": "2022-01-21T05:27:00.176297Z"
+     "iopub.execute_input": "2023-09-07T01:00:43.590367Z",
+     "iopub.status.busy": "2023-09-07T01:00:43.590304Z",
+     "iopub.status.idle": "2023-09-07T01:00:45.409205Z",
+     "shell.execute_reply": "2023-09-07T01:00:45.408764Z"
     },
     "papermill": {
-     "duration": 155.031153,
-     "end_time": "2022-01-21T05:27:00.176905",
+     "duration": 1.821721,
+     "end_time": "2023-09-07T01:00:45.410033",
      "exception": false,
-     "start_time": "2022-01-21T05:24:25.145752",
+     "start_time": "2023-09-07T01:00:43.588312",
      "status": "completed"
     },
     "tags": []
@@ -1009,7 +1018,23 @@
      "name": "stderr",
      "output_type": "stream",
      "text": [
-      "gtex_v8_data_whole_blood-var_pc_log2: 100%|█████████████████████████| 54/54 [02:35<00:00,  2.87s/it]\n"
+      "gtex_v8_data_whole_blood-var_pc_log2:   0%|                                   | 0/1 [00:00<?, ?it/s]"
+     ]
+    },
+    {
+     "data": {
+      "text/plain": [
+       "1.7388567924499512"
+      ]
+     },
+     "metadata": {},
+     "output_type": "display_data"
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "gtex_v8_data_whole_blood-var_pc_log2: 100%|███████████████████████████| 1/1 [00:01<00:00,  1.82s/it]\n"
      ]
     }
    ],
@@ -1042,10 +1067,10 @@
    "id": "258babdf-03ce-4450-ab22-7a3d75bf6869",
    "metadata": {
     "papermill": {
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-     "end_time": "2022-01-21T05:27:00.268011",
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      "exception": false,
-     "start_time": "2022-01-21T05:27:00.223067",
+     "start_time": "2023-09-07T01:00:45.412305",
      "status": "completed"
     },
     "tags": []
@@ -1078,14 +1103,14 @@
   },
   "papermill": {
    "default_parameters": {},
-   "duration": 161.894784,
-   "end_time": "2022-01-21T05:27:00.622937",
+   "duration": 6.767244,
+   "end_time": "2023-09-07T01:00:45.534810",
    "environment_variables": {},
    "exception": null,
    "input_path": "nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.ipynb",
    "output_path": "nbs/10_compute_correlations/05_gtex_v8/05_01-gtex-var_pc_log2-pearson.run.ipynb",
    "parameters": {},
-   "start_time": "2022-01-21T05:24:18.728153",
+   "start_time": "2023-09-07T01:00:38.767566",
    "version": "2.3.3"
   }
  },
diff --git a/nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.ipynb b/nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.ipynb
index cf32729a..bd7ffbf0 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.ipynb
+++ b/nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.ipynb
@@ -5,10 +5,10 @@
    "id": "e9773a95-e8fd-4963-87a5-0c92299434d5",
    "metadata": {
     "papermill": {
-     "duration": 0.046947,
-     "end_time": "2022-01-21T05:27:04.093247",
+     "duration": 0.002119,
+     "end_time": "2023-09-07T01:00:47.151603",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.046300",
+     "start_time": "2023-09-07T01:00:47.149484",
      "status": "completed"
     },
     "tags": []
@@ -22,10 +22,10 @@
    "id": "57f34c74-404d-4776-b547-e6acb2df75d7",
    "metadata": {
     "papermill": {
-     "duration": 0.012804,
-     "end_time": "2022-01-21T05:27:04.122836",
+     "duration": 0.001185,
+     "end_time": "2023-09-07T01:00:47.154346",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.110032",
+     "start_time": "2023-09-07T01:00:47.153161",
      "status": "completed"
     },
     "tags": []
@@ -42,10 +42,10 @@
    "id": "1d8fae6b-e623-46a6-aff6-d7849163c820",
    "metadata": {
     "papermill": {
-     "duration": 0.012894,
-     "end_time": "2022-01-21T05:27:04.148534",
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      "exception": false,
-     "start_time": "2022-01-21T05:27:04.135640",
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      "status": "completed"
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     "tags": []
@@ -60,16 +60,16 @@
    "id": "76729f0e-f742-495b-b676-d9d7b1539e10",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.180988Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.180528Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.627027Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.626501Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.161465Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.161328Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.379656Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.379392Z"
     },
     "papermill": {
-     "duration": 0.465647,
-     "end_time": "2022-01-21T05:27:04.627139",
+     "duration": 0.220992,
+     "end_time": "2023-09-07T01:00:47.380602",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.161492",
+     "start_time": "2023-09-07T01:00:47.159610",
      "status": "completed"
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     "tags": []
@@ -91,10 +91,10 @@
    "id": "a6c3a546-9a49-45e7-9f17-fbdb5af4bfb6",
    "metadata": {
     "papermill": {
-     "duration": 0.012816,
-     "end_time": "2022-01-21T05:27:04.653690",
+     "duration": 0.00965,
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      "exception": false,
-     "start_time": "2022-01-21T05:27:04.640874",
+     "start_time": "2023-09-07T01:00:47.382192",
      "status": "completed"
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     "tags": []
@@ -109,16 +109,16 @@
    "id": "56ff94d3-a230-4028-a71d-518ac109209b",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.683053Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.682578Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.684238Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.684580Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.399947Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.399872Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.401946Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.401654Z"
     },
     "papermill": {
-     "duration": 0.018037,
-     "end_time": "2022-01-21T05:27:04.684698",
+     "duration": 0.006204,
+     "end_time": "2023-09-07T01:00:47.402741",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.666661",
+     "start_time": "2023-09-07T01:00:47.396537",
      "status": "completed"
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     "tags": []
@@ -130,9 +130,22 @@
   },
   {
    "cell_type": "code",
-   "execution_count": null,
+   "execution_count": 3,
    "id": "a9b9f8b2",
    "metadata": {
+    "execution": {
+     "iopub.execute_input": "2023-09-07T01:00:47.407682Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.407575Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.409888Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.409600Z"
+    },
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+     "start_time": "2023-09-07T01:00:47.404814",
+     "status": "completed"
+    },
     "tags": []
    },
    "outputs": [],
@@ -149,20 +162,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 3,
+   "execution_count": 4,
    "id": "8baf4209-ba56-4e3d-b60f-6ce2bb686159",
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-     "shell.execute_reply": "2022-01-21T05:27:04.721686Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.416107Z",
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     "papermill": {
-     "duration": 0.023934,
-     "end_time": "2022-01-21T05:27:04.722233",
+     "duration": 0.007553,
+     "end_time": "2023-09-07T01:00:47.421149",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.698299",
+     "start_time": "2023-09-07T01:00:47.413596",
      "status": "completed"
     },
     "tags": []
@@ -187,20 +200,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 4,
+   "execution_count": 5,
    "id": "21a3e349-9a09-4d24-89e3-915fdbf08a81",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.752941Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.752494Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.753952Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.754304Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.425093Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.424974Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.426203Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.426056Z"
     },
     "papermill": {
-     "duration": 0.018105,
-     "end_time": "2022-01-21T05:27:04.754415",
+     "duration": 0.003661,
+     "end_time": "2023-09-07T01:00:47.426807",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.736310",
+     "start_time": "2023-09-07T01:00:47.423146",
      "status": "completed"
     },
     "tags": []
@@ -215,10 +228,10 @@
    "id": "b0afcba9-5847-414e-b448-f0cd08ecd8ce",
    "metadata": {
     "papermill": {
-     "duration": 0.013305,
-     "end_time": "2022-01-21T05:27:04.781426",
+     "duration": 0.001252,
+     "end_time": "2023-09-07T01:00:47.429485",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.768121",
+     "start_time": "2023-09-07T01:00:47.428233",
      "status": "completed"
     },
     "tags": []
@@ -229,20 +242,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 5,
+   "execution_count": 6,
    "id": "35760114-8560-4a0e-ad4f-2bee9104c63d",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.812358Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.811854Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.814255Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.814619Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.432526Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.432441Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.434015Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.433888Z"
     },
     "papermill": {
-     "duration": 0.020015,
-     "end_time": "2022-01-21T05:27:04.814733",
+     "duration": 0.003615,
+     "end_time": "2023-09-07T01:00:47.434557",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.794718",
+     "start_time": "2023-09-07T01:00:47.430942",
      "status": "completed"
     },
     "tags": []
@@ -267,20 +280,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 6,
+   "execution_count": 7,
    "id": "f1418e81-4e77-4f67-b5ed-b29b797e31a0",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.847292Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.846749Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.849601Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.849166Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.437475Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.437390Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.439008Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.438882Z"
     },
     "papermill": {
-     "duration": 0.020466,
-     "end_time": "2022-01-21T05:27:04.849692",
+     "duration": 0.003625,
+     "end_time": "2023-09-07T01:00:47.439506",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.829226",
+     "start_time": "2023-09-07T01:00:47.435881",
      "status": "completed"
     },
     "tags": []
@@ -307,10 +320,10 @@
    "id": "5fdf8df6-eba0-4cf5-979c-3acd56a5ef3c",
    "metadata": {
     "papermill": {
-     "duration": 0.014012,
-     "end_time": "2022-01-21T05:27:04.878246",
+     "duration": 0.001248,
+     "end_time": "2023-09-07T01:00:47.442083",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.864234",
+     "start_time": "2023-09-07T01:00:47.440835",
      "status": "completed"
     },
     "tags": []
@@ -321,20 +334,45 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 7,
+   "execution_count": 8,
    "id": "596d25ed-4120-4bef-8984-a91ae6529ab5",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:04.910458Z",
-     "iopub.status.busy": "2022-01-21T05:27:04.909917Z",
-     "iopub.status.idle": "2022-01-21T05:27:04.914655Z",
-     "shell.execute_reply": "2022-01-21T05:27:04.915006Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.444989Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.444892Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.446148Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.446013Z"
+    },
+    "papermill": {
+     "duration": 0.00325,
+     "end_time": "2023-09-07T01:00:47.446665",
+     "exception": false,
+     "start_time": "2023-09-07T01:00:47.443415",
+     "status": "completed"
+    },
+    "tags": []
+   },
+   "outputs": [],
+   "source": [
+    "tissue_in_file_names = [f\"_data_{simplify_string(t.lower())}-\" for t in TISSUES]"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 9,
+   "id": "5fadd2c5",
+   "metadata": {
+    "execution": {
+     "iopub.execute_input": "2023-09-07T01:00:47.449538Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.449456Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.451848Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.451729Z"
     },
     "papermill": {
-     "duration": 0.022631,
-     "end_time": "2022-01-21T05:27:04.915117",
+     "duration": 0.004239,
+     "end_time": "2023-09-07T01:00:47.452241",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.892486",
+     "start_time": "2023-09-07T01:00:47.448002",
      "status": "completed"
     },
     "tags": []
@@ -343,7 +381,7 @@
     {
      "data": {
       "text/plain": [
-       "54"
+       "1"
       ]
      },
      "metadata": {},
@@ -352,29 +390,13 @@
     {
      "data": {
       "text/plain": [
-       "[PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_subcutaneous-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_visceral_omentum-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adrenal_gland-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_artery_aorta-var_pc_log2.pkl'),\n",
-       " PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_artery_coronary-var_pc_log2.pkl')]"
+       "[PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_whole_blood-var_pc_log2.pkl')]"
       ]
      },
      "metadata": {},
      "output_type": "display_data"
     }
    ],
-   "source": [
-    "tissue_in_file_names = [f\"_data_{simplify_string(t.lower())}-\" for t in TISSUES]"
-   ]
-  },
-  {
-   "cell_type": "code",
-   "execution_count": null,
-   "id": "5fadd2c5",
-   "metadata": {
-    "tags": []
-   },
-   "outputs": [],
    "source": [
     "input_files = sorted(list(INPUT_DIR.glob(f\"*-{GENE_SELECTION_STRATEGY}.pkl\")))\n",
     "input_files = [\n",
@@ -391,10 +413,10 @@
    "id": "081da632-fd12-462a-9ae1-c0ceccf1bb5d",
    "metadata": {
     "papermill": {
-     "duration": 0.014562,
-     "end_time": "2022-01-21T05:27:04.944643",
+     "duration": 0.00132,
+     "end_time": "2023-09-07T01:00:47.454936",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.930081",
+     "start_time": "2023-09-07T01:00:47.453616",
      "status": "completed"
     },
     "tags": []
@@ -408,10 +430,10 @@
    "id": "37137fff-2d3a-43d8-9bd5-d7c3284a97f5",
    "metadata": {
     "papermill": {
-     "duration": 0.014593,
-     "end_time": "2022-01-21T05:27:04.973725",
+     "duration": 0.001323,
+     "end_time": "2023-09-07T01:00:47.457617",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.959132",
+     "start_time": "2023-09-07T01:00:47.456294",
      "status": "completed"
     },
     "tags": []
@@ -422,20 +444,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 8,
+   "execution_count": 10,
    "id": "5dd40707-759f-4bf9-b8cc-84811b2dfe53",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:05.006650Z",
-     "iopub.status.busy": "2022-01-21T05:27:05.006132Z",
-     "iopub.status.idle": "2022-01-21T05:27:05.019712Z",
-     "shell.execute_reply": "2022-01-21T05:27:05.019254Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.460609Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.460523Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.469932Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.469775Z"
     },
     "papermill": {
-     "duration": 0.03141,
-     "end_time": "2022-01-21T05:27:05.019809",
+     "duration": 0.011531,
+     "end_time": "2023-09-07T01:00:47.470523",
      "exception": false,
-     "start_time": "2022-01-21T05:27:04.988399",
+     "start_time": "2023-09-07T01:00:47.458992",
      "status": "completed"
     },
     "tags": []
@@ -444,7 +466,7 @@
     {
      "data": {
       "text/plain": [
-       "PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_adipose_subcutaneous-var_pc_log2.pkl')"
+       "PosixPath('/opt/data/results/gtex_v8/gene_selection/gtex_v8_data_whole_blood-var_pc_log2.pkl')"
       ]
      },
      "metadata": {},
@@ -458,20 +480,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 9,
+   "execution_count": 11,
    "id": "e8acd036-93f7-46c0-a1ee-8da0c2c24790",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:05.054317Z",
-     "iopub.status.busy": "2022-01-21T05:27:05.053785Z",
-     "iopub.status.idle": "2022-01-21T05:27:05.056668Z",
-     "shell.execute_reply": "2022-01-21T05:27:05.056143Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.473750Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.473635Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.475207Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.475085Z"
     },
     "papermill": {
-     "duration": 0.021639,
-     "end_time": "2022-01-21T05:27:05.056759",
+     "duration": 0.003641,
+     "end_time": "2023-09-07T01:00:47.475712",
      "exception": false,
-     "start_time": "2022-01-21T05:27:05.035120",
+     "start_time": "2023-09-07T01:00:47.472071",
      "status": "completed"
     },
     "tags": []
@@ -480,10 +502,10 @@
     {
      "data": {
       "text/plain": [
-       "(500, 663)"
+       "(500, 755)"
       ]
      },
-     "execution_count": 9,
+     "execution_count": 11,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -494,20 +516,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 10,
+   "execution_count": 12,
    "id": "111e360b-dbe4-4b69-9029-7b7669eb5ddc",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:05.102738Z",
-     "iopub.status.busy": "2022-01-21T05:27:05.094553Z",
-     "iopub.status.idle": "2022-01-21T05:27:05.112766Z",
-     "shell.execute_reply": "2022-01-21T05:27:05.112380Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.478884Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.478780Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.486401Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.486275Z"
     },
     "papermill": {
-     "duration": 0.039032,
-     "end_time": "2022-01-21T05:27:05.112863",
+     "duration": 0.00988,
+     "end_time": "2023-09-07T01:00:47.487068",
      "exception": false,
-     "start_time": "2022-01-21T05:27:05.073831",
+     "start_time": "2023-09-07T01:00:47.477188",
      "status": "completed"
     },
     "tags": []
@@ -534,27 +556,27 @@
        "  <thead>\n",
        "    <tr style=\"text-align: right;\">\n",
        "      <th></th>\n",
-       "      <th>GTEX-1117F-0226-SM-5GZZ7</th>\n",
-       "      <th>GTEX-111CU-1826-SM-5GZYN</th>\n",
-       "      <th>GTEX-111FC-0226-SM-5N9B8</th>\n",
-       "      <th>GTEX-111VG-2326-SM-5N9BK</th>\n",
-       "      <th>GTEX-111YS-2426-SM-5GZZQ</th>\n",
-       "      <th>GTEX-1122O-2026-SM-9YFMG</th>\n",
-       "      <th>GTEX-1128S-2126-SM-5H12U</th>\n",
-       "      <th>GTEX-113IC-0226-SM-5HL5C</th>\n",
-       "      <th>GTEX-117YX-2226-SM-5EGJJ</th>\n",
-       "      <th>GTEX-11DXW-0326-SM-5H11W</th>\n",
+       "      <th>GTEX-111YS-0006-SM-5NQBE</th>\n",
+       "      <th>GTEX-1122O-0005-SM-5O99J</th>\n",
+       "      <th>GTEX-1128S-0005-SM-5P9HI</th>\n",
+       "      <th>GTEX-113IC-0006-SM-5NQ9C</th>\n",
+       "      <th>GTEX-113JC-0006-SM-5O997</th>\n",
+       "      <th>GTEX-117XS-0005-SM-5PNU6</th>\n",
+       "      <th>GTEX-117YW-0005-SM-5NQ8Z</th>\n",
+       "      <th>GTEX-1192W-0005-SM-5NQBQ</th>\n",
+       "      <th>GTEX-1192X-0005-SM-5NQC3</th>\n",
+       "      <th>GTEX-11DXW-0006-SM-5NQ7Y</th>\n",
        "      <th>...</th>\n",
-       "      <th>GTEX-ZXES-2026-SM-5NQ6R</th>\n",
-       "      <th>GTEX-ZXG5-0226-SM-59HJI</th>\n",
-       "      <th>GTEX-ZYFC-0326-SM-5NQ7H</th>\n",
-       "      <th>GTEX-ZYFD-0226-SM-5NQ86</th>\n",
-       "      <th>GTEX-ZYT6-0326-SM-7LG5R</th>\n",
-       "      <th>GTEX-ZYVF-0226-SM-5GIEG</th>\n",
-       "      <th>GTEX-ZYW4-0226-SM-5E44M</th>\n",
-       "      <th>GTEX-ZYY3-0226-SM-5E45M</th>\n",
-       "      <th>GTEX-ZZ64-1626-SM-5E43W</th>\n",
-       "      <th>GTEX-ZZPU-2726-SM-5NQ8O</th>\n",
+       "      <th>GTEX-ZVE2-0006-SM-51MRW</th>\n",
+       "      <th>GTEX-ZVP2-0005-SM-51MRK</th>\n",
+       "      <th>GTEX-ZVT2-0005-SM-57WBW</th>\n",
+       "      <th>GTEX-ZVT3-0006-SM-51MT9</th>\n",
+       "      <th>GTEX-ZVT4-0006-SM-57WB8</th>\n",
+       "      <th>GTEX-ZVTK-0006-SM-57WBK</th>\n",
+       "      <th>GTEX-ZVZP-0006-SM-51MSW</th>\n",
+       "      <th>GTEX-ZVZQ-0006-SM-51MR8</th>\n",
+       "      <th>GTEX-ZXES-0005-SM-57WCB</th>\n",
+       "      <th>GTEX-ZXG5-0005-SM-57WCN</th>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>gene_ens_id</th>\n",
@@ -583,215 +605,215 @@
        "  </thead>\n",
        "  <tbody>\n",
        "    <tr>\n",
-       "      <th>ENSG00000129824.15</th>\n",
-       "      <td>0.9301</td>\n",
-       "      <td>270.4000</td>\n",
-       "      <td>345.8000</td>\n",
-       "      <td>242.20</td>\n",
-       "      <td>180.800</td>\n",
-       "      <td>0.1904</td>\n",
-       "      <td>0.18640</td>\n",
-       "      <td>294.40</td>\n",
-       "      <td>332.6000</td>\n",
-       "      <td>216.0000</td>\n",
+       "      <th>ENSG00000169429.10</th>\n",
+       "      <td>0.5623</td>\n",
+       "      <td>0.8067</td>\n",
+       "      <td>116.90000</td>\n",
+       "      <td>4.047</td>\n",
+       "      <td>211.0</td>\n",
+       "      <td>58.110</td>\n",
+       "      <td>68.38</td>\n",
+       "      <td>249.50</td>\n",
+       "      <td>5.095</td>\n",
+       "      <td>295.9</td>\n",
        "      <td>...</td>\n",
-       "      <td>0.2916</td>\n",
-       "      <td>311.700</td>\n",
-       "      <td>230.0000</td>\n",
-       "      <td>302.20000</td>\n",
-       "      <td>316.500</td>\n",
-       "      <td>0.2567</td>\n",
-       "      <td>340.2000</td>\n",
-       "      <td>0.6962</td>\n",
-       "      <td>269.1000</td>\n",
-       "      <td>0.1917</td>\n",
+       "      <td>39.960</td>\n",
+       "      <td>0.1393</td>\n",
+       "      <td>0.22380</td>\n",
+       "      <td>245.0</td>\n",
+       "      <td>513.6</td>\n",
+       "      <td>1626.00</td>\n",
+       "      <td>0.5633</td>\n",
+       "      <td>515.70</td>\n",
+       "      <td>1.19400</td>\n",
+       "      <td>1163.00</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <td>100.4000</td>\n",
-       "      <td>785.1000</td>\n",
-       "      <td>14.0000</td>\n",
-       "      <td>44.48</td>\n",
-       "      <td>17.960</td>\n",
-       "      <td>2.5670</td>\n",
-       "      <td>0.18410</td>\n",
-       "      <td>46.91</td>\n",
-       "      <td>13.9500</td>\n",
-       "      <td>0.1953</td>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <td>0.6529</td>\n",
+       "      <td>1.3850</td>\n",
+       "      <td>199.20000</td>\n",
+       "      <td>2.266</td>\n",
+       "      <td>116.7</td>\n",
+       "      <td>192.300</td>\n",
+       "      <td>161.50</td>\n",
+       "      <td>263.50</td>\n",
+       "      <td>23.540</td>\n",
+       "      <td>251.9</td>\n",
        "      <td>...</td>\n",
-       "      <td>3.9480</td>\n",
-       "      <td>108.800</td>\n",
-       "      <td>3.8230</td>\n",
-       "      <td>6.61700</td>\n",
-       "      <td>11.440</td>\n",
-       "      <td>7.6190</td>\n",
-       "      <td>27.4300</td>\n",
-       "      <td>21.0200</td>\n",
-       "      <td>122.6000</td>\n",
-       "      <td>10.8200</td>\n",
+       "      <td>114.300</td>\n",
+       "      <td>1.8330</td>\n",
+       "      <td>0.41150</td>\n",
+       "      <td>149.0</td>\n",
+       "      <td>935.3</td>\n",
+       "      <td>233.60</td>\n",
+       "      <td>0.8882</td>\n",
+       "      <td>134.00</td>\n",
+       "      <td>1.12000</td>\n",
+       "      <td>295.70</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000134184.12</th>\n",
-       "      <td>75.6800</td>\n",
-       "      <td>0.2281</td>\n",
-       "      <td>0.2070</td>\n",
-       "      <td>0.00</td>\n",
-       "      <td>36.930</td>\n",
-       "      <td>0.1651</td>\n",
-       "      <td>0.06058</td>\n",
-       "      <td>174.00</td>\n",
-       "      <td>0.1429</td>\n",
-       "      <td>56.4700</td>\n",
+       "      <th>ENSG00000163631.16</th>\n",
+       "      <td>1.8480</td>\n",
+       "      <td>0.2503</td>\n",
+       "      <td>0.08429</td>\n",
+       "      <td>1.251</td>\n",
+       "      <td>1348.0</td>\n",
+       "      <td>9.971</td>\n",
+       "      <td>101.30</td>\n",
+       "      <td>95.09</td>\n",
+       "      <td>1.264</td>\n",
+       "      <td>119.3</td>\n",
        "      <td>...</td>\n",
-       "      <td>54.9200</td>\n",
-       "      <td>46.230</td>\n",
-       "      <td>0.1468</td>\n",
-       "      <td>0.04705</td>\n",
-       "      <td>67.240</td>\n",
-       "      <td>0.4005</td>\n",
-       "      <td>0.5507</td>\n",
-       "      <td>56.0600</td>\n",
-       "      <td>0.4048</td>\n",
-       "      <td>0.0000</td>\n",
+       "      <td>2.092</td>\n",
+       "      <td>2.1100</td>\n",
+       "      <td>0.03588</td>\n",
+       "      <td>171.8</td>\n",
+       "      <td>107.1</td>\n",
+       "      <td>71.25</td>\n",
+       "      <td>1.7720</td>\n",
+       "      <td>309.60</td>\n",
+       "      <td>0.07361</td>\n",
+       "      <td>17.75</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000224114.1</th>\n",
-       "      <td>1.1500</td>\n",
-       "      <td>0.8068</td>\n",
-       "      <td>0.5856</td>\n",
-       "      <td>74.28</td>\n",
-       "      <td>0.314</td>\n",
-       "      <td>0.6115</td>\n",
-       "      <td>49.95000</td>\n",
-       "      <td>139.60</td>\n",
-       "      <td>83.5400</td>\n",
-       "      <td>1.3640</td>\n",
+       "      <th>ENSG00000277632.1</th>\n",
+       "      <td>1.6960</td>\n",
+       "      <td>1.3450</td>\n",
+       "      <td>235.10000</td>\n",
+       "      <td>11.770</td>\n",
+       "      <td>141.7</td>\n",
+       "      <td>199.100</td>\n",
+       "      <td>525.50</td>\n",
+       "      <td>659.90</td>\n",
+       "      <td>10.910</td>\n",
+       "      <td>209.3</td>\n",
        "      <td>...</td>\n",
-       "      <td>0.1915</td>\n",
-       "      <td>5.593</td>\n",
-       "      <td>60.0200</td>\n",
-       "      <td>61.04000</td>\n",
-       "      <td>1.596</td>\n",
-       "      <td>81.6000</td>\n",
-       "      <td>149.4000</td>\n",
-       "      <td>0.2032</td>\n",
-       "      <td>1.2270</td>\n",
-       "      <td>0.5036</td>\n",
+       "      <td>61.340</td>\n",
+       "      <td>2.2500</td>\n",
+       "      <td>0.72310</td>\n",
+       "      <td>261.2</td>\n",
+       "      <td>400.0</td>\n",
+       "      <td>288.50</td>\n",
+       "      <td>2.6960</td>\n",
+       "      <td>287.50</td>\n",
+       "      <td>3.32300</td>\n",
+       "      <td>618.90</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000173432.10</th>\n",
-       "      <td>2765.0000</td>\n",
-       "      <td>241.1000</td>\n",
-       "      <td>1.5220</td>\n",
-       "      <td>99.98</td>\n",
-       "      <td>921.400</td>\n",
-       "      <td>2859.0000</td>\n",
-       "      <td>3874.00000</td>\n",
-       "      <td>21.41</td>\n",
-       "      <td>1338.0000</td>\n",
-       "      <td>61.4800</td>\n",
+       "      <th>ENSG00000239839.6</th>\n",
+       "      <td>185.2000</td>\n",
+       "      <td>1.7790</td>\n",
+       "      <td>694.30000</td>\n",
+       "      <td>23.840</td>\n",
+       "      <td>297.3</td>\n",
+       "      <td>3122.000</td>\n",
+       "      <td>2521.00</td>\n",
+       "      <td>1504.00</td>\n",
+       "      <td>80.060</td>\n",
+       "      <td>652.0</td>\n",
        "      <td>...</td>\n",
-       "      <td>1666.0000</td>\n",
-       "      <td>165.300</td>\n",
-       "      <td>81.9700</td>\n",
-       "      <td>180.90000</td>\n",
-       "      <td>24.650</td>\n",
-       "      <td>276.2000</td>\n",
-       "      <td>53.5400</td>\n",
-       "      <td>1436.0000</td>\n",
-       "      <td>140.5000</td>\n",
-       "      <td>756.3000</td>\n",
+       "      <td>1010.000</td>\n",
+       "      <td>253.8000</td>\n",
+       "      <td>94.52000</td>\n",
+       "      <td>6083.0</td>\n",
+       "      <td>2768.0</td>\n",
+       "      <td>52.06</td>\n",
+       "      <td>34.5700</td>\n",
+       "      <td>17.36</td>\n",
+       "      <td>352.30000</td>\n",
+       "      <td>63.85</td>\n",
        "    </tr>\n",
        "  </tbody>\n",
        "</table>\n",
-       "<p>5 rows × 663 columns</p>\n",
+       "<p>5 rows × 755 columns</p>\n",
        "</div>"
       ],
       "text/plain": [
-       "                    GTEX-1117F-0226-SM-5GZZ7  GTEX-111CU-1826-SM-5GZYN  \\\n",
+       "                    GTEX-111YS-0006-SM-5NQBE  GTEX-1122O-0005-SM-5O99J  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                    0.9301                  270.4000   \n",
-       "ENSG00000149968.11                  100.4000                  785.1000   \n",
-       "ENSG00000134184.12                   75.6800                    0.2281   \n",
-       "ENSG00000224114.1                     1.1500                    0.8068   \n",
-       "ENSG00000173432.10                 2765.0000                  241.1000   \n",
+       "ENSG00000169429.10                    0.5623                    0.8067   \n",
+       "ENSG00000135245.9                     0.6529                    1.3850   \n",
+       "ENSG00000163631.16                    1.8480                    0.2503   \n",
+       "ENSG00000277632.1                     1.6960                    1.3450   \n",
+       "ENSG00000239839.6                   185.2000                    1.7790   \n",
        "\n",
-       "                    GTEX-111FC-0226-SM-5N9B8  GTEX-111VG-2326-SM-5N9BK  \\\n",
+       "                    GTEX-1128S-0005-SM-5P9HI  GTEX-113IC-0006-SM-5NQ9C  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                  345.8000                    242.20   \n",
-       "ENSG00000149968.11                   14.0000                     44.48   \n",
-       "ENSG00000134184.12                    0.2070                      0.00   \n",
-       "ENSG00000224114.1                     0.5856                     74.28   \n",
-       "ENSG00000173432.10                    1.5220                     99.98   \n",
+       "ENSG00000169429.10                 116.90000                     4.047   \n",
+       "ENSG00000135245.9                  199.20000                     2.266   \n",
+       "ENSG00000163631.16                   0.08429                     1.251   \n",
+       "ENSG00000277632.1                  235.10000                    11.770   \n",
+       "ENSG00000239839.6                  694.30000                    23.840   \n",
        "\n",
-       "                    GTEX-111YS-2426-SM-5GZZQ  GTEX-1122O-2026-SM-9YFMG  \\\n",
+       "                    GTEX-113JC-0006-SM-5O997  GTEX-117XS-0005-SM-5PNU6  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                   180.800                    0.1904   \n",
-       "ENSG00000149968.11                    17.960                    2.5670   \n",
-       "ENSG00000134184.12                    36.930                    0.1651   \n",
-       "ENSG00000224114.1                      0.314                    0.6115   \n",
-       "ENSG00000173432.10                   921.400                 2859.0000   \n",
+       "ENSG00000169429.10                     211.0                    58.110   \n",
+       "ENSG00000135245.9                      116.7                   192.300   \n",
+       "ENSG00000163631.16                    1348.0                     9.971   \n",
+       "ENSG00000277632.1                      141.7                   199.100   \n",
+       "ENSG00000239839.6                      297.3                  3122.000   \n",
        "\n",
-       "                    GTEX-1128S-2126-SM-5H12U  GTEX-113IC-0226-SM-5HL5C  \\\n",
+       "                    GTEX-117YW-0005-SM-5NQ8Z  GTEX-1192W-0005-SM-5NQBQ  \\\n",
        "gene_ens_id                                                              \n",
-       "ENSG00000129824.15                   0.18640                    294.40   \n",
-       "ENSG00000149968.11                   0.18410                     46.91   \n",
-       "ENSG00000134184.12                   0.06058                    174.00   \n",
-       "ENSG00000224114.1                   49.95000                    139.60   \n",
-       "ENSG00000173432.10                3874.00000                     21.41   \n",
+       "ENSG00000169429.10                     68.38                    249.50   \n",
+       "ENSG00000135245.9                     161.50                    263.50   \n",
+       "ENSG00000163631.16                    101.30                     95.09   \n",
+       "ENSG00000277632.1                     525.50                    659.90   \n",
+       "ENSG00000239839.6                    2521.00                   1504.00   \n",
        "\n",
-       "                    GTEX-117YX-2226-SM-5EGJJ  GTEX-11DXW-0326-SM-5H11W  ...  \\\n",
+       "                    GTEX-1192X-0005-SM-5NQC3  GTEX-11DXW-0006-SM-5NQ7Y  ...  \\\n",
        "gene_ens_id                                                             ...   \n",
-       "ENSG00000129824.15                  332.6000                  216.0000  ...   \n",
-       "ENSG00000149968.11                   13.9500                    0.1953  ...   \n",
-       "ENSG00000134184.12                    0.1429                   56.4700  ...   \n",
-       "ENSG00000224114.1                    83.5400                    1.3640  ...   \n",
-       "ENSG00000173432.10                 1338.0000                   61.4800  ...   \n",
+       "ENSG00000169429.10                     5.095                     295.9  ...   \n",
+       "ENSG00000135245.9                     23.540                     251.9  ...   \n",
+       "ENSG00000163631.16                     1.264                     119.3  ...   \n",
+       "ENSG00000277632.1                     10.910                     209.3  ...   \n",
+       "ENSG00000239839.6                     80.060                     652.0  ...   \n",
        "\n",
-       "                    GTEX-ZXES-2026-SM-5NQ6R  GTEX-ZXG5-0226-SM-59HJI  \\\n",
+       "                    GTEX-ZVE2-0006-SM-51MRW  GTEX-ZVP2-0005-SM-51MRK  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                   0.2916                  311.700   \n",
-       "ENSG00000149968.11                   3.9480                  108.800   \n",
-       "ENSG00000134184.12                  54.9200                   46.230   \n",
-       "ENSG00000224114.1                    0.1915                    5.593   \n",
-       "ENSG00000173432.10                1666.0000                  165.300   \n",
+       "ENSG00000169429.10                   39.960                   0.1393   \n",
+       "ENSG00000135245.9                   114.300                   1.8330   \n",
+       "ENSG00000163631.16                    2.092                   2.1100   \n",
+       "ENSG00000277632.1                    61.340                   2.2500   \n",
+       "ENSG00000239839.6                  1010.000                 253.8000   \n",
        "\n",
-       "                    GTEX-ZYFC-0326-SM-5NQ7H  GTEX-ZYFD-0226-SM-5NQ86  \\\n",
+       "                    GTEX-ZVT2-0005-SM-57WBW  GTEX-ZVT3-0006-SM-51MT9  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                 230.0000                302.20000   \n",
-       "ENSG00000149968.11                   3.8230                  6.61700   \n",
-       "ENSG00000134184.12                   0.1468                  0.04705   \n",
-       "ENSG00000224114.1                   60.0200                 61.04000   \n",
-       "ENSG00000173432.10                  81.9700                180.90000   \n",
+       "ENSG00000169429.10                  0.22380                    245.0   \n",
+       "ENSG00000135245.9                   0.41150                    149.0   \n",
+       "ENSG00000163631.16                  0.03588                    171.8   \n",
+       "ENSG00000277632.1                   0.72310                    261.2   \n",
+       "ENSG00000239839.6                  94.52000                   6083.0   \n",
        "\n",
-       "                    GTEX-ZYT6-0326-SM-7LG5R  GTEX-ZYVF-0226-SM-5GIEG  \\\n",
+       "                    GTEX-ZVT4-0006-SM-57WB8  GTEX-ZVTK-0006-SM-57WBK  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                  316.500                   0.2567   \n",
-       "ENSG00000149968.11                   11.440                   7.6190   \n",
-       "ENSG00000134184.12                   67.240                   0.4005   \n",
-       "ENSG00000224114.1                     1.596                  81.6000   \n",
-       "ENSG00000173432.10                   24.650                 276.2000   \n",
+       "ENSG00000169429.10                    513.6                  1626.00   \n",
+       "ENSG00000135245.9                     935.3                   233.60   \n",
+       "ENSG00000163631.16                    107.1                    71.25   \n",
+       "ENSG00000277632.1                     400.0                   288.50   \n",
+       "ENSG00000239839.6                    2768.0                    52.06   \n",
        "\n",
-       "                    GTEX-ZYW4-0226-SM-5E44M  GTEX-ZYY3-0226-SM-5E45M  \\\n",
+       "                    GTEX-ZVZP-0006-SM-51MSW  GTEX-ZVZQ-0006-SM-51MR8  \\\n",
        "gene_ens_id                                                            \n",
-       "ENSG00000129824.15                 340.2000                   0.6962   \n",
-       "ENSG00000149968.11                  27.4300                  21.0200   \n",
-       "ENSG00000134184.12                   0.5507                  56.0600   \n",
-       "ENSG00000224114.1                  149.4000                   0.2032   \n",
-       "ENSG00000173432.10                  53.5400                1436.0000   \n",
+       "ENSG00000169429.10                   0.5633                   515.70   \n",
+       "ENSG00000135245.9                    0.8882                   134.00   \n",
+       "ENSG00000163631.16                   1.7720                   309.60   \n",
+       "ENSG00000277632.1                    2.6960                   287.50   \n",
+       "ENSG00000239839.6                   34.5700                    17.36   \n",
        "\n",
-       "                    GTEX-ZZ64-1626-SM-5E43W  GTEX-ZZPU-2726-SM-5NQ8O  \n",
+       "                    GTEX-ZXES-0005-SM-57WCB  GTEX-ZXG5-0005-SM-57WCN  \n",
        "gene_ens_id                                                           \n",
-       "ENSG00000129824.15                 269.1000                   0.1917  \n",
-       "ENSG00000149968.11                 122.6000                  10.8200  \n",
-       "ENSG00000134184.12                   0.4048                   0.0000  \n",
-       "ENSG00000224114.1                    1.2270                   0.5036  \n",
-       "ENSG00000173432.10                 140.5000                 756.3000  \n",
+       "ENSG00000169429.10                  1.19400                  1163.00  \n",
+       "ENSG00000135245.9                   1.12000                   295.70  \n",
+       "ENSG00000163631.16                  0.07361                    17.75  \n",
+       "ENSG00000277632.1                   3.32300                   618.90  \n",
+       "ENSG00000239839.6                 352.30000                    63.85  \n",
        "\n",
-       "[5 rows x 663 columns]"
+       "[5 rows x 755 columns]"
       ]
      },
-     "execution_count": 10,
+     "execution_count": 12,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -805,10 +827,10 @@
    "id": "5903f3f5-791e-4f03-9d79-600102933d04",
    "metadata": {
     "papermill": {
-     "duration": 0.016489,
-     "end_time": "2022-01-21T05:27:05.146066",
+     "duration": 0.001461,
+     "end_time": "2023-09-07T01:00:47.490124",
      "exception": false,
-     "start_time": "2022-01-21T05:27:05.129577",
+     "start_time": "2023-09-07T01:00:47.488663",
      "status": "completed"
     },
     "tags": []
@@ -819,20 +841,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 11,
+   "execution_count": 13,
    "id": "118a6631-1cfd-44a3-bd85-5ec7118edd03",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-21T05:27:05.181291Z",
-     "iopub.status.busy": "2022-01-21T05:27:05.180823Z",
-     "iopub.status.idle": "2022-01-21T05:27:05.189078Z",
-     "shell.execute_reply": "2022-01-21T05:27:05.188704Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.493589Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.493466Z",
+     "iopub.status.idle": "2023-09-07T01:00:47.496815Z",
+     "shell.execute_reply": "2023-09-07T01:00:47.496692Z"
     },
     "papermill": {
-     "duration": 0.027234,
-     "end_time": "2022-01-21T05:27:05.189174",
+     "duration": 0.005534,
+     "end_time": "2023-09-07T01:00:47.497193",
      "exception": false,
-     "start_time": "2022-01-21T05:27:05.161940",
+     "start_time": "2023-09-07T01:00:47.491659",
      "status": "completed"
     },
     "tags": []
@@ -868,9 +890,9 @@
        "  <thead>\n",
        "    <tr style=\"text-align: right;\">\n",
        "      <th>gene_ens_id</th>\n",
-       "      <th>ENSG00000129824.15</th>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <th>ENSG00000134184.12</th>\n",
+       "      <th>ENSG00000169429.10</th>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <th>ENSG00000163631.16</th>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>gene_ens_id</th>\n",
@@ -881,21 +903,21 @@
        "  </thead>\n",
        "  <tbody>\n",
        "    <tr>\n",
-       "      <th>ENSG00000129824.15</th>\n",
+       "      <th>ENSG00000169429.10</th>\n",
        "      <td>1.000000</td>\n",
-       "      <td>0.404501</td>\n",
-       "      <td>0.016874</td>\n",
+       "      <td>0.853836</td>\n",
+       "      <td>0.709240</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000149968.11</th>\n",
-       "      <td>0.404501</td>\n",
+       "      <th>ENSG00000135245.9</th>\n",
+       "      <td>0.853836</td>\n",
        "      <td>1.000000</td>\n",
-       "      <td>-0.062548</td>\n",
+       "      <td>0.675719</td>\n",
        "    </tr>\n",
        "    <tr>\n",
-       "      <th>ENSG00000134184.12</th>\n",
-       "      <td>0.016874</td>\n",
-       "      <td>-0.062548</td>\n",
+       "      <th>ENSG00000163631.16</th>\n",
+       "      <td>0.709240</td>\n",
+       "      <td>0.675719</td>\n",
        "      <td>1.000000</td>\n",
        "    </tr>\n",
        "  </tbody>\n",
@@ -903,11 +925,11 @@
        "</div>"
       ],
       "text/plain": [
-       "gene_ens_id         ENSG00000129824.15  ENSG00000149968.11  ENSG00000134184.12\n",
-       "gene_ens_id                                                                   \n",
-       "ENSG00000129824.15            1.000000            0.404501            0.016874\n",
-       "ENSG00000149968.11            0.404501            1.000000           -0.062548\n",
-       "ENSG00000134184.12            0.016874           -0.062548            1.000000"
+       "gene_ens_id         ENSG00000169429.10  ENSG00000135245.9  ENSG00000163631.16\n",
+       "gene_ens_id                                                                  \n",
+       "ENSG00000169429.10            1.000000           0.853836            0.709240\n",
+       "ENSG00000135245.9             0.853836           1.000000            0.675719\n",
+       "ENSG00000163631.16            0.709240           0.675719            1.000000"
       ]
      },
      "metadata": {},
@@ -923,20 +945,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 12,
+   "execution_count": 14,
    "id": "d32281d8-f640-4f87-a1d5-aefa0757e9c3",
    "metadata": {
     "execution": {
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-     "iopub.status.idle": "2022-01-21T05:27:10.765426Z",
-     "shell.execute_reply": "2022-01-21T05:27:10.764976Z"
+     "iopub.execute_input": "2023-09-07T01:00:47.500602Z",
+     "iopub.status.busy": "2023-09-07T01:00:47.500519Z",
+     "iopub.status.idle": "2023-09-07T01:00:48.124696Z",
+     "shell.execute_reply": "2023-09-07T01:00:48.124427Z"
     },
     "papermill": {
-     "duration": 5.558914,
-     "end_time": "2022-01-21T05:27:10.765525",
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      "exception": false,
-     "start_time": "2022-01-21T05:27:05.206611",
+     "start_time": "2023-09-07T01:00:47.498784",
      "status": "completed"
     },
     "tags": []
@@ -946,7 +968,7 @@
      "name": "stdout",
      "output_type": "stream",
      "text": [
-      "68.4 ms ± 318 µs per loop (mean ± std. dev. of 7 runs, 10 loops each)\n"
+      "29.6 ms ± 0 ns per loop (mean ± std. dev. of 1 run, 10 loops each)\n"
      ]
     }
    ],
@@ -959,10 +981,10 @@
    "id": "fc2f7184-c0da-438c-94f5-002912793636",
    "metadata": {
     "papermill": {
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-     "end_time": "2022-01-21T05:27:10.800155",
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-     "start_time": "2022-01-21T05:27:10.783122",
+     "start_time": "2023-09-07T01:00:48.127085",
      "status": "completed"
     },
     "tags": []
@@ -973,20 +995,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 13,
+   "execution_count": 15,
    "id": "1237ae45-d4fc-4074-bfc7-a1de75aeea48",
    "metadata": {
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-     "shell.execute_reply": "2022-01-21T05:29:52.216435Z"
+     "iopub.execute_input": "2023-09-07T01:00:48.132464Z",
+     "iopub.status.busy": "2023-09-07T01:00:48.132407Z",
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     },
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-     "end_time": "2022-01-21T05:29:52.217491",
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      "exception": false,
-     "start_time": "2022-01-21T05:27:10.817223",
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      "status": "completed"
     },
     "tags": []
@@ -996,7 +1018,23 @@
      "name": "stderr",
      "output_type": "stream",
      "text": [
-      "gtex_v8_data_whole_blood-var_pc_log2: 100%|█████████████████████████| 54/54 [02:41<00:00,  2.99s/it]\n"
+      "gtex_v8_data_whole_blood-var_pc_log2:   0%|                                   | 0/1 [00:00<?, ?it/s]"
+     ]
+    },
+    {
+     "data": {
+      "text/plain": [
+       "2.0522382259368896"
+      ]
+     },
+     "metadata": {},
+     "output_type": "display_data"
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "gtex_v8_data_whole_blood-var_pc_log2: 100%|███████████████████████████| 1/1 [00:02<00:00,  2.16s/it]\n"
      ]
     }
    ],
@@ -1029,10 +1067,10 @@
    "id": "258babdf-03ce-4450-ab22-7a3d75bf6869",
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@@ -1061,18 +1099,18 @@
    "name": "python",
    "nbconvert_exporter": "python",
    "pygments_lexer": "ipython3",
-   "version": "3.9.9"
+   "version": "3.9.12"
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+   "end_time": "2023-09-07T01:00:50.419857",
    "environment_variables": {},
    "exception": null,
    "input_path": "nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.ipynb",
    "output_path": "nbs/10_compute_correlations/05_gtex_v8/06_01-gtex-var_pc_log2-spearman.run.ipynb",
    "parameters": {},
-   "start_time": "2022-01-21T05:27:02.835916",
+   "start_time": "2023-09-07T01:00:46.346515",
    "version": "2.3.3"
   }
  },
diff --git a/nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.ipynb b/nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.ipynb
index 6e42bcc0..d0b22a34 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.ipynb
+++ b/nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.ipynb
@@ -5,10 +5,10 @@
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@@ -22,10 +22,10 @@
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@@ -42,10 +42,10 @@
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@@ -60,16 +60,16 @@
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-     "shell.execute_reply": "2022-05-24T14:46:59.170627Z"
+     "iopub.execute_input": "2023-09-07T02:50:46.950464Z",
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@@ -91,10 +91,10 @@
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@@ -109,16 +109,16 @@
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-     "shell.execute_reply": "2022-05-24T14:46:59.195465Z"
+     "iopub.execute_input": "2023-09-07T02:50:47.196345Z",
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@@ -134,16 +134,16 @@
    "id": "f5433907-5b88-4c68-b3d4-fb98298dec4a",
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-     "shell.execute_reply": "2022-05-24T14:46:59.210092Z"
+     "iopub.execute_input": "2023-09-07T02:50:47.201717Z",
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@@ -163,19 +163,55 @@
   {
    "cell_type": "code",
    "execution_count": 4,
+   "id": "8fd0656d-e9cc-410b-baa9-96b57538c4c1",
+   "metadata": {
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+     "iopub.status.busy": "2023-09-07T02:50:47.206999Z",
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+     "start_time": "2023-09-07T02:50:47.204704",
+     "status": "completed"
+    },
+    "tags": []
+   },
+   "outputs": [
+    {
+     "data": {
+      "text/plain": [
+       "20"
+      ]
+     },
+     "execution_count": 4,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "conf.GENERAL[\"N_JOBS\"]"
+   ]
+  },
+  {
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+   "execution_count": 5,
    "id": "8baf4209-ba56-4e3d-b60f-6ce2bb686159",
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-     "shell.execute_reply": "2022-05-24T14:46:59.231532Z"
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@@ -184,7 +220,7 @@
     {
      "data": {
       "text/plain": [
-       "'clustermatch'"
+       "'ccc'"
       ]
      },
      "metadata": {},
@@ -201,20 +237,20 @@
   },
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-   "execution_count": 5,
+   "execution_count": 6,
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-     "shell.execute_reply": "2022-05-24T14:46:59.246434Z"
+     "iopub.execute_input": "2023-09-07T02:50:47.218354Z",
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@@ -229,10 +265,10 @@
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@@ -243,20 +279,20 @@
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+     "iopub.execute_input": "2023-09-07T02:50:47.225212Z",
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@@ -281,20 +317,20 @@
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@@ -321,10 +357,10 @@
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@@ -335,20 +371,20 @@
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@@ -360,20 +396,20 @@
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@@ -431,10 +467,10 @@
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@@ -445,20 +481,20 @@
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@@ -481,20 +517,20 @@
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@@ -506,7 +542,7 @@
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@@ -517,20 +553,20 @@
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@@ -814,7 +850,7 @@
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@@ -828,10 +864,10 @@
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@@ -842,20 +878,20 @@
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@@ -946,20 +982,20 @@
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@@ -969,7 +1005,7 @@
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      "text": [
-      "5min 30s ± 0 ns per loop (mean ± std. dev. of 1 run, 1 loop each)\n"
+      "2min 10s ± 0 ns per loop (mean ± std. dev. of 1 run, 1 loop each)\n"
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@@ -982,10 +1018,10 @@
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@@ -996,42 +1032,47 @@
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    "outputs": [
     {
-     "data": {
-      "text/plain": [
-       "'gtex_v8_data_whole_blood-var_pc_log2'"
-      ]
-     },
-     "metadata": {},
-     "output_type": "display_data"
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "gtex_v8_data_whole_blood-var_pc_log2:   0%|                                   | 0/1 [00:00<?, ?it/s]"
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     {
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-       "33313.81599831581"
+       "13169.536622524261"
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      "metadata": {},
      "output_type": "display_data"
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "gtex_v8_data_whole_blood-var_pc_log2: 100%|██████████████████████| 1/1 [3:39:29<00:00, 13169.61s/it]\n"
+     ]
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@@ -1063,10 +1104,10 @@
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@@ -1099,14 +1140,14 @@
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+   "input_path": "nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.ipynb",
+   "output_path": "nbs/10_compute_correlations/05_gtex_v8/07_01-gtex-var_pc_log2-ccc.run.ipynb",
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diff --git a/nbs/10_compute_correlations/05_gtex_v8/08_01-gtex-var_pc_log2-mic_e-parallel.ipynb b/nbs/10_compute_correlations/05_gtex_v8/08_01-gtex-var_pc_log2-mic_e-parallel.ipynb
index cfa53512..06dbce39 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/08_01-gtex-var_pc_log2-mic_e-parallel.ipynb
+++ b/nbs/10_compute_correlations/05_gtex_v8/08_01-gtex-var_pc_log2-mic_e-parallel.ipynb
@@ -5,10 +5,10 @@
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@@ -22,10 +22,10 @@
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@@ -42,10 +42,10 @@
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@@ -60,16 +60,16 @@
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@@ -90,10 +90,10 @@
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@@ -108,16 +108,16 @@
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@@ -133,16 +133,16 @@
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    "metadata": {
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@@ -162,19 +162,55 @@
   {
    "cell_type": "code",
    "execution_count": 4,
+   "id": "9f5e3822-c91a-466e-a4d9-04f369b28602",
+   "metadata": {
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+     "iopub.execute_input": "2023-09-07T06:34:46.368574Z",
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+     "status": "completed"
+    },
+    "tags": []
+   },
+   "outputs": [
+    {
+     "data": {
+      "text/plain": [
+       "20"
+      ]
+     },
+     "execution_count": 4,
+     "metadata": {},
+     "output_type": "execute_result"
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+   ],
+   "source": [
+    "conf.GENERAL[\"N_JOBS\"]"
+   ]
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    "id": "8baf4209-ba56-4e3d-b60f-6ce2bb686159",
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@@ -203,20 +239,20 @@
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@@ -231,10 +267,10 @@
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@@ -245,20 +281,20 @@
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@@ -283,20 +319,20 @@
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@@ -323,10 +359,10 @@
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@@ -337,20 +373,20 @@
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    "metadata": {
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+     "iopub.execute_input": "2023-09-07T06:34:46.402725Z",
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+     "iopub.status.idle": "2023-09-07T06:34:46.403893Z",
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@@ -362,20 +398,20 @@
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@@ -416,10 +452,10 @@
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@@ -433,10 +469,10 @@
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@@ -447,20 +483,20 @@
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    "id": "5dd40707-759f-4bf9-b8cc-84811b2dfe53",
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+     "iopub.execute_input": "2023-09-07T06:34:46.419329Z",
+     "iopub.status.busy": "2023-09-07T06:34:46.419246Z",
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@@ -483,20 +519,20 @@
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-     "shell.execute_reply": "2022-05-25T00:13:31.749415Z"
+     "iopub.execute_input": "2023-09-07T06:34:46.433898Z",
+     "iopub.status.busy": "2023-09-07T06:34:46.433790Z",
+     "iopub.status.idle": "2023-09-07T06:34:46.435258Z",
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      "status": "completed"
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     "tags": []
@@ -508,7 +544,7 @@
        "(500, 755)"
       ]
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-     "execution_count": 11,
+     "execution_count": 12,
      "metadata": {},
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     }
@@ -519,20 +555,20 @@
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-   "execution_count": 12,
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    "id": "111e360b-dbe4-4b69-9029-7b7669eb5ddc",
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-     "shell.execute_reply": "2022-05-25T00:13:31.780754Z"
+     "iopub.execute_input": "2023-09-07T06:34:46.439083Z",
+     "iopub.status.busy": "2023-09-07T06:34:46.438997Z",
+     "iopub.status.idle": "2023-09-07T06:34:46.446753Z",
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      "status": "completed"
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     "tags": []
@@ -816,7 +852,7 @@
        "[5 rows x 755 columns]"
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-     "execution_count": 12,
+     "execution_count": 13,
      "metadata": {},
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@@ -830,10 +866,10 @@
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@@ -844,20 +880,20 @@
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@@ -948,20 +984,20 @@
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@@ -971,7 +1007,7 @@
      "name": "stdout",
      "output_type": "stream",
      "text": [
-      "1h 7min 54s ± 0 ns per loop (mean ± std. dev. of 1 run, 1 loop each)\n"
+      "7min 53s ± 0 ns per loop (mean ± std. dev. of 1 run, 1 loop each)\n"
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@@ -984,10 +1020,10 @@
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diff --git a/nbs/10_compute_correlations/05_gtex_v8/50-combine_all.ipynb b/nbs/10_compute_correlations/05_gtex_v8/50-combine_all.ipynb
index 85698b5c..4c3ffe3a 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/50-combine_all.ipynb
+++ b/nbs/10_compute_correlations/05_gtex_v8/50-combine_all.ipynb
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@@ -2138,20 +2138,20 @@
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@@ -2163,20 +2163,20 @@
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@@ -2214,7 +2214,7 @@
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@@ -2225,20 +2225,20 @@
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@@ -2255,7 +2255,7 @@
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@@ -2266,20 +2266,20 @@
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@@ -2291,20 +2291,20 @@
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@@ -2316,20 +2316,20 @@
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@@ -2342,20 +2342,20 @@
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@@ -2367,7 +2367,7 @@
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@@ -2378,20 +2378,20 @@
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@@ -2408,7 +2408,7 @@
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@@ -2419,20 +2419,20 @@
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@@ -2444,20 +2444,20 @@
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@@ -2475,20 +2475,20 @@
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     "execution": {
-     "iopub.execute_input": "2022-01-24T16:39:09.433667Z",
-     "iopub.status.busy": "2022-01-24T16:39:09.433173Z",
-     "iopub.status.idle": "2022-01-24T16:39:09.461449Z",
-     "shell.execute_reply": "2022-01-24T16:39:09.460897Z"
+     "iopub.execute_input": "2023-09-07T18:55:34.706953Z",
+     "iopub.status.busy": "2023-09-07T18:55:34.706865Z",
+     "iopub.status.idle": "2023-09-07T18:55:34.730129Z",
+     "shell.execute_reply": "2023-09-07T18:55:34.729916Z"
     },
     "papermill": {
-     "duration": 0.070905,
-     "end_time": "2022-01-24T16:39:09.461565",
+     "duration": 0.027704,
+     "end_time": "2023-09-07T18:55:34.730798",
      "exception": false,
-     "start_time": "2022-01-24T16:39:09.390660",
+     "start_time": "2023-09-07T18:55:34.703094",
      "status": "completed"
     },
     "tags": []
@@ -2500,20 +2500,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 43,
+   "execution_count": 42,
    "id": "baf842f9-d6c8-48b7-bffe-8eb05c73d7de",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-24T16:39:09.548697Z",
-     "iopub.status.busy": "2022-01-24T16:39:09.548014Z",
-     "iopub.status.idle": "2022-01-24T16:39:09.551154Z",
-     "shell.execute_reply": "2022-01-24T16:39:09.550708Z"
+     "iopub.execute_input": "2023-09-07T18:55:34.738521Z",
+     "iopub.status.busy": "2023-09-07T18:55:34.738365Z",
+     "iopub.status.idle": "2023-09-07T18:55:34.740106Z",
+     "shell.execute_reply": "2023-09-07T18:55:34.739973Z"
     },
     "papermill": {
-     "duration": 0.046311,
-     "end_time": "2022-01-24T16:39:09.551248",
+     "duration": 0.005969,
+     "end_time": "2023-09-07T18:55:34.740548",
      "exception": false,
-     "start_time": "2022-01-24T16:39:09.504937",
+     "start_time": "2023-09-07T18:55:34.734579",
      "status": "completed"
     },
     "tags": []
@@ -2525,7 +2525,7 @@
        "(12497500, 3)"
       ]
      },
-     "execution_count": 43,
+     "execution_count": 42,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -2536,20 +2536,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 44,
+   "execution_count": 43,
    "id": "3bd226fe-0c9d-4b69-8250-e22ccaf3730f",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-24T16:39:09.639835Z",
-     "iopub.status.busy": "2022-01-24T16:39:09.639206Z",
-     "iopub.status.idle": "2022-01-24T16:39:09.642428Z",
-     "shell.execute_reply": "2022-01-24T16:39:09.641989Z"
+     "iopub.execute_input": "2023-09-07T18:55:34.747574Z",
+     "iopub.status.busy": "2023-09-07T18:55:34.747460Z",
+     "iopub.status.idle": "2023-09-07T18:55:34.750602Z",
+     "shell.execute_reply": "2023-09-07T18:55:34.750463Z"
     },
     "papermill": {
-     "duration": 0.050826,
-     "end_time": "2022-01-24T16:39:09.642520",
+     "duration": 0.007234,
+     "end_time": "2023-09-07T18:55:34.751105",
      "exception": false,
-     "start_time": "2022-01-24T16:39:09.591694",
+     "start_time": "2023-09-07T18:55:34.743871",
      "status": "completed"
     },
     "tags": []
@@ -2577,7 +2577,7 @@
        "    <tr style=\"text-align: right;\">\n",
        "      <th></th>\n",
        "      <th></th>\n",
-       "      <th>clustermatch</th>\n",
+       "      <th>ccc</th>\n",
        "      <th>pearson</th>\n",
        "      <th>spearman</th>\n",
        "    </tr>\n",
@@ -2619,15 +2619,15 @@
        "</div>"
       ],
       "text/plain": [
-       "                                       clustermatch   pearson  spearman\n",
-       "ENSG00000000419.12 ENSG00000002834.17      0.418721  0.681847  0.786595\n",
-       "                   ENSG00000002919.14      0.405090  0.734699  0.816991\n",
-       "                   ENSG00000002933.7       0.007466  0.013825  0.004128\n",
-       "                   ENSG00000003402.19      0.391683  0.727347  0.803653\n",
-       "                   ENSG00000004478.7       0.099013  0.094147  0.231269"
+       "                                            ccc   pearson  spearman\n",
+       "ENSG00000000419.12 ENSG00000002834.17  0.418721  0.681847  0.786595\n",
+       "                   ENSG00000002919.14  0.405090  0.734699  0.816991\n",
+       "                   ENSG00000002933.7   0.007466  0.013825  0.004128\n",
+       "                   ENSG00000003402.19  0.391683  0.727347  0.803653\n",
+       "                   ENSG00000004478.7   0.099013  0.094147  0.231269"
       ]
      },
-     "execution_count": 44,
+     "execution_count": 43,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -2641,10 +2641,10 @@
    "id": "24a50051-141d-4ba0-ad33-3123b4afc1b6",
    "metadata": {
     "papermill": {
-     "duration": 0.03998,
-     "end_time": "2022-01-24T16:39:09.723193",
+     "duration": 0.003329,
+     "end_time": "2023-09-07T18:55:34.757826",
      "exception": false,
-     "start_time": "2022-01-24T16:39:09.683213",
+     "start_time": "2023-09-07T18:55:34.754497",
      "status": "completed"
     },
     "tags": []
@@ -2655,20 +2655,20 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 45,
+   "execution_count": 44,
    "id": "2f20fdf4-a44a-48c0-bbe1-8def473ac2a5",
    "metadata": {
     "execution": {
-     "iopub.execute_input": "2022-01-24T16:39:09.807006Z",
-     "iopub.status.busy": "2022-01-24T16:39:09.806543Z",
-     "iopub.status.idle": "2022-01-24T16:39:09.993322Z",
-     "shell.execute_reply": "2022-01-24T16:39:09.992766Z"
+     "iopub.execute_input": "2023-09-07T18:55:34.764918Z",
+     "iopub.status.busy": "2023-09-07T18:55:34.764853Z",
+     "iopub.status.idle": "2023-09-07T18:55:34.936622Z",
+     "shell.execute_reply": "2023-09-07T18:55:34.936430Z"
     },
     "papermill": {
-     "duration": 0.229981,
-     "end_time": "2022-01-24T16:39:09.993435",
+     "duration": 0.176352,
+     "end_time": "2023-09-07T18:55:34.937535",
      "exception": false,
-     "start_time": "2022-01-24T16:39:09.763454",
+     "start_time": "2023-09-07T18:55:34.761183",
      "status": "completed"
     },
     "tags": []
@@ -2684,10 +2684,10 @@
    "id": "8f464a7f-b76f-4898-8bf5-074eabd33626",
    "metadata": {
     "papermill": {
-     "duration": 0.040435,
-     "end_time": "2022-01-24T16:39:10.077889",
+     "duration": 0.003456,
+     "end_time": "2023-09-07T18:55:34.944719",
      "exception": false,
-     "start_time": "2022-01-24T16:39:10.037454",
+     "start_time": "2023-09-07T18:55:34.941263",
      "status": "completed"
     },
     "tags": []
@@ -2720,8 +2720,8 @@
   },
   "papermill": {
    "default_parameters": {},
-   "duration": 53.158221,
-   "end_time": "2022-01-24T16:39:10.324915",
+   "duration": 21.618719,
+   "end_time": "2023-09-07T18:55:35.062437",
    "environment_variables": {},
    "exception": null,
    "input_path": "nbs/10_compute_correlations/05_gtex_v8/50-combine_all.ipynb",
@@ -2729,7 +2729,7 @@
    "parameters": {
     "GTEX_TISSUE": "skin_sun_exposed_lower_leg"
    },
-   "start_time": "2022-01-24T16:38:17.166694",
+   "start_time": "2023-09-07T18:55:13.443718",
    "version": "2.3.3"
   }
  },
diff --git a/nbs/10_compute_correlations/05_gtex_v8/py/07_01-gtex-var_pc_log2-ccc.py b/nbs/10_compute_correlations/05_gtex_v8/py/07_01-gtex-var_pc_log2-ccc.py
index 05381e2e..a255a182 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/py/07_01-gtex-var_pc_log2-ccc.py
+++ b/nbs/10_compute_correlations/05_gtex_v8/py/07_01-gtex-var_pc_log2-ccc.py
@@ -51,6 +51,9 @@
     # "Artery - Tibial",
 ]
 
+# %% tags=[]
+conf.GENERAL["N_JOBS"]
+
 # %% tags=[]
 CORRELATION_METHOD = lambda x: ccc(x, n_jobs=conf.GENERAL["N_JOBS"])
 CORRELATION_METHOD.__name__ = "ccc"
diff --git a/nbs/10_compute_correlations/05_gtex_v8/py/08_01-gtex-var_pc_log2-mic_e-parallel.py b/nbs/10_compute_correlations/05_gtex_v8/py/08_01-gtex-var_pc_log2-mic_e-parallel.py
index 3ff685ef..fea487c9 100644
--- a/nbs/10_compute_correlations/05_gtex_v8/py/08_01-gtex-var_pc_log2-mic_e-parallel.py
+++ b/nbs/10_compute_correlations/05_gtex_v8/py/08_01-gtex-var_pc_log2-mic_e-parallel.py
@@ -50,6 +50,9 @@
     # "Artery - Tibial",
 ]
 
+# %% tags=[]
+conf.GENERAL["N_JOBS"]
+
 
 # %% tags=[]
 def mic_parallel(data):