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TODO.md

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TODO

  1. Complex feature candidates:
  • Columns to have:
    • Index nr

    • Subunits

    • From fraction (left sec)
    • To fraction (right sec)
    • Cluster score (intra-group correlation)
    • Subunits (Separated list of Uniprot IDs)
    • Intensity-based stoichiometry (colon-separated, e.g. 1:2:3, must have same order as subunits column)
    • Estimated MW (SUM(Intensity-based stoichiometry * MW_subunits))
    • Apparent MW (convertSECtoMW(Right_SEC - Left_SEC))
    • Delta von App, Est
  • Rows have to be orderable on all columns
  • convertSECtoMW:
    • log10(MW), dann linreg zu SEC position
  1. On hover over complex feature rows:
  • Fade all protein traces to gray
  • Highlight traces of subunits with red or similar
  • Gray box between left sec and right sec
  • Vline for estimated MW
  1. Trace plot:
  • Vary line type as well
  • Zweite Achse on top fuer convertSECtoMW(SEC)
  1. SEC friends:
  • Find for a given protein other proteins that correlate well
    • either globally
    • or within the complex feature boundaries
  • Button "Find similar proteins" auf complex feature row
    • Results in list sorted by correlation score
    • Hover over each subunit plots the full trace into the trace window and adjusts the molecular weight vline.
    • Button "Add" on each additional subunit candidate. Pressing it adds the protein to the complex feature. Process can be repeated...
  1. Additional Id inputs:
  • Gene name
  • Evtl. uniprot name