diff --git a/CHANGELOG.md b/CHANGELOG.md
index 8e5947320ebe..094fd2929697 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -9,6 +9,7 @@
 
 - `[jest-runtime]` Fix issue where user cannot utilize dynamic import despite specifying `--experimental-vm-modules` Node option ([#15842](https://github.com/jestjs/jest/pull/15842))
 - `[jest-test-sequencer]` Fix issue where failed tests due to compilation errors not getting re-executed even with `--onlyFailures` CLI option ([#15851](https://github.com/jestjs/jest/pull/15851))
+- `[jest-config]` Fix issue where Jest test deps `@jest/test-sequencer` and `jest-environment-node` cannot be resolved correctly when used in `pnpm`-based monorepo ([#15877](https://github.com/jestjs/jest/pull/15877))
 
 ### Chore & Maintenance
 
diff --git a/packages/jest-config/src/__tests__/normalize.test.ts b/packages/jest-config/src/__tests__/normalize.test.ts
index 3939302c890a..ba7c6c091b5d 100644
--- a/packages/jest-config/src/__tests__/normalize.test.ts
+++ b/packages/jest-config/src/__tests__/normalize.test.ts
@@ -15,6 +15,7 @@ import Defaults from '../Defaults';
 import {DEFAULT_JS_PATTERN} from '../constants';
 import normalize, {type AllOptions} from '../normalize';
 
+const env = {...process.env};
 const DEFAULT_CSS_PATTERN = '\\.(css)$';
 
 jest
@@ -85,6 +86,7 @@ beforeEach(() => {
 
 afterEach(() => {
   jest.mocked(console.warn).mockRestore();
+  process.env = env;
 });
 
 it('picks an id based on the rootDir', async () => {
@@ -814,6 +816,21 @@ describe('testEnvironment', () => {
     );
   });
 
+  it('resolves to node environment if given arg matches with default value', async () => {
+    process.env.npm_config_user_agent = 'pnpm';
+    const {options} = await normalize(
+      {
+        rootDir: '/root',
+        testEnvironment: 'node',
+      },
+      {} as Config.Argv,
+    );
+
+    expect(options.testEnvironment).toEqual(
+      require.resolve('jest-environment-node'),
+    );
+  });
+
   it('throws on invalid environment names', async () => {
     await expect(
       normalize(
@@ -2204,3 +2221,20 @@ describe('runInBand', () => {
     expect(options.runInBand).toBe(true);
   });
 });
+
+describe('testSequencer', () => {
+  it('resolves to @jest/test-sequencer if given arg matches with default value and pnpm is used', async () => {
+    process.env.npm_config_user_agent = 'pnpm';
+    const {options} = await normalize(
+      {
+        rootDir: '/root/path/foo',
+        testSequencer: '@jest/test-sequencer',
+      },
+      {} as Config.Argv,
+    );
+
+    expect(options.testSequencer).toMatch(
+      require.resolve('@jest/test-sequencer'),
+    );
+  });
+});
diff --git a/packages/jest-config/src/__tests__/utils.test.ts b/packages/jest-config/src/__tests__/utils.test.ts
new file mode 100644
index 000000000000..b8a2784f57ef
--- /dev/null
+++ b/packages/jest-config/src/__tests__/utils.test.ts
@@ -0,0 +1,47 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ */
+
+import {tmpdir} from 'os';
+import {useSpecificPackageManager} from '../utils';
+import path from 'path';
+import {cleanup, writeFiles} from '../../../../e2e/Utils';
+
+const DIR = path.resolve(tmpdir(), 'jest_config_utils_test');
+const env = {...process.env};
+
+beforeEach(() => {
+  cleanup(DIR);
+});
+
+afterEach(() => {
+  process.env = env;
+  cleanup(DIR);
+});
+
+describe('useSpecificPackageManager', () => {
+  it('returns true when package manager matches with arg is used', () => {
+    writeFiles(DIR, {
+      'pnpm-lock.yaml': "lockfileVersion: '9.0'",
+    });
+    process.env.npm_config_user_agent = 'pnpm';
+    expect(useSpecificPackageManager('pnpm', DIR)).toBe(true);
+  });
+
+  it('returns true when package manager is not used but signature lockfile can be found', () => {
+    writeFiles(DIR, {
+      'pnpm-lock.yaml': "lockfileVersion: '9.0'",
+    });
+    process.env.npm_config_user_agent = 'node';
+    expect(useSpecificPackageManager('pnpm', DIR)).toBe(true);
+  });
+
+  it('returns false when package manager different from arg is used', () => {
+    process.env.npm_config_user_agent = 'something_else';
+    expect(useSpecificPackageManager('npm', DIR)).toBe(false);
+  });
+});
diff --git a/packages/jest-config/src/normalize.ts b/packages/jest-config/src/normalize.ts
index e2ed840cf020..89e3a57ade3f 100644
--- a/packages/jest-config/src/normalize.ts
+++ b/packages/jest-config/src/normalize.ts
@@ -49,6 +49,7 @@ import {
   escapeGlobCharacters,
   replaceRootDirInPath,
   resolve,
+  useSpecificPackageManager,
 } from './utils';
 
 const ERROR = `${BULLET}Validation Error`;
@@ -169,7 +170,9 @@ const setupPreset = async (
           );
         }
         throw createConfigError(
-          `  Preset ${chalk.bold(presetPath)} not found relative to rootDir ${chalk.bold(options.rootDir)}.`,
+          `  Preset ${chalk.bold(
+            presetPath,
+          )} not found relative to rootDir ${chalk.bold(options.rootDir)}.`,
         );
       }
       throw createConfigError(
@@ -518,12 +521,20 @@ export default async function normalize(
     options.setupFilesAfterEnv = [];
   }
 
+  // For default Jest test env, let's use native resolution mechanism
+  // of JS runtime instead of resorting to third-party ones.
+  let testEnvironment = options.testEnvironment;
+  if (
+    `jest-environment-${testEnvironment}` === DEFAULT_CONFIG.testEnvironment &&
+    useSpecificPackageManager('pnpm', options.rootDir)
+  ) {
+    testEnvironment = require.resolve(DEFAULT_CONFIG.testEnvironment);
+  }
   options.testEnvironment = resolveTestEnvironment({
     requireResolveFunction: requireResolve,
     rootDir: options.rootDir,
     testEnvironment:
-      options.testEnvironment ||
-      require.resolve(DEFAULT_CONFIG.testEnvironment),
+      testEnvironment || require.resolve(DEFAULT_CONFIG.testEnvironment),
   });
 
   if (!options.roots) {
@@ -997,9 +1008,17 @@ export default async function normalize(
     // ignored
   }
 
+  // For default Jest test sequencer, let's use native resolution mechanism
+  // of JS runtime instead of resorting to third-party ones.
+  let testSequencer = options.testSequencer;
+  if (
+    options.testSequencer === DEFAULT_CONFIG.testSequencer &&
+    useSpecificPackageManager('pnpm', options.rootDir)
+  ) {
+    testSequencer = require.resolve(DEFAULT_CONFIG.testSequencer);
+  }
   newOptions.testSequencer = resolveSequencer(newOptions.resolver, {
-    filePath:
-      options.testSequencer || require.resolve(DEFAULT_CONFIG.testSequencer),
+    filePath: testSequencer || require.resolve(DEFAULT_CONFIG.testSequencer),
     requireResolveFunction: requireResolve,
     rootDir: options.rootDir,
   });
diff --git a/packages/jest-config/src/utils.ts b/packages/jest-config/src/utils.ts
index 0ce93cf316bc..b50b7cd66992 100644
--- a/packages/jest-config/src/utils.ts
+++ b/packages/jest-config/src/utils.ts
@@ -7,6 +7,7 @@
 
 import * as path from 'path';
 import chalk from 'chalk';
+import {existsSync} from 'graceful-fs';
 import Resolver from 'jest-resolve';
 import {ValidationError} from 'jest-validate';
 
@@ -119,3 +120,16 @@ export const isJSONString = (text?: JSONString | string): text is JSONString =>
   typeof text === 'string' &&
   text.startsWith('{') &&
   text.endsWith('}');
+
+export const useSpecificPackageManager = (
+  identifier: string,
+  rootDir: string,
+): boolean => {
+  let checkLockFile = false;
+  if (identifier === 'pnpm') {
+    checkLockFile = existsSync(path.join(rootDir, 'pnpm-lock.yaml'));
+  }
+  return (
+    checkLockFile || !!process.env.npm_config_user_agent?.includes(identifier)
+  );
+};