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lines changed Original file line number Diff line number Diff line change @@ -652,9 +652,9 @@ \subsection{Aligning short genomic reads}
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to high quality. This allowed us to construct an independent truth variant
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dataset~\citep {Li223297 } for
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ERR1341796. In this evaluation, minimap2 has higher SNP false negative rate
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- (FNR; 2.5 \% of minimap2 vs 2.2 \% of BWA-MEM), but fewer false positive SNPs per
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- million bases (FPPM; 3 .0 vs 3.9 ), lower 2--50bp INDEL FNR (7.3 \% vs 7.5 \% ) and
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- similar INDEL FPPM (both 1.0 ). Minimap2 is broadly similar to BWA-MEM in the
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+ (FNR; 2.6 \% of minimap2 vs 2.3 \% of BWA-MEM), but fewer false positive SNPs per
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+ million bases (FPPM; 7 .0 vs 8.8 ), similar INDEL FNR (11.2 \% vs 11.3 \% ) and
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+ similar INDEL FPPM (6.4 vs 6.5 ). Minimap2 is broadly comparable to BWA-MEM in the
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context of small variant calling.
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\subsection {Aligning long-read assemblies }
@@ -717,6 +717,8 @@ \section*{Acknowledgements}
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BWA-MEM. We are also grateful to minimap2 users who have greatly helped to
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suggest features and to fix various issues.
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+ \paragraph {Funding\textcolon } NHGRI 1R01HG010040-01
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\bibliography {minimap2}
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\end {document }
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