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51.html
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<!DOCTYPE html>
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<head>
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<p><strong>Title:</strong> The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis</p>
<p><strong>Year Published:</strong> 2012</p>
<p><strong>Observation:</strong> Downregulation of GPNMB increased motor neuron vulnerability. Fragments of GPNMB in spinal cord attenuated the neurotoxicity of SOD1 G93A mice</p>
<p><strong>Comment:</strong> GPNMB can be a target for therapeutic intervention in ALS</p>
<p><strong>Citation:</strong> Tanaka, H., Shimazawa, M., Kimura, M., Takata, M., Tsuruma, K., Yamada, M., … Hara, H. (2012). The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis. Scientific Reports, 2, 573. doi:10.1038/srep00573</p>
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