diff --git a/cmake/onnxruntime_python.cmake b/cmake/onnxruntime_python.cmake
index d2c022e4e0269..5a87252b08573 100644
--- a/cmake/onnxruntime_python.cmake
+++ b/cmake/onnxruntime_python.cmake
@@ -170,6 +170,7 @@ target_link_libraries(onnxruntime_pybind11_state PRIVATE
     onnxruntime_session
     ${onnxruntime_libs}
     ${PROVIDERS_NNAPI}
+    ${PROVIDERS_VSINPU}
     ${PROVIDERS_XNNPACK}
     ${PROVIDERS_COREML}
     ${PROVIDERS_RKNPU}
@@ -1018,4 +1019,13 @@ if (onnxruntime_USE_QNN)
   endif()
 endif()
 
+if (onnxruntime_USE_VSINPU)
+  add_custom_command(
+    TARGET onnxruntime_pybind11_state POST_BUILD
+    COMMAND ${CMAKE_COMMAND} -E copy
+        $<TARGET_FILE:onnxruntime_providers_vsinpu>
+        $<TARGET_FILE_DIR:${build_output_target}>/onnxruntime/capi/
+  )
+endif()
+
 endif()
diff --git a/onnxruntime/python/onnxruntime_pybind_schema.cc b/onnxruntime/python/onnxruntime_pybind_schema.cc
index 1319e8f6fe959..77503c2ef4fcb 100644
--- a/onnxruntime/python/onnxruntime_pybind_schema.cc
+++ b/onnxruntime/python/onnxruntime_pybind_schema.cc
@@ -69,6 +69,9 @@ void addGlobalSchemaFunctions(pybind11::module& m) {
 #ifdef USE_NNAPI
             onnxruntime::NnapiProviderFactoryCreator::Create(0, std::optional<std::string>()),
 #endif
+#ifdef USE_VSINPU
+            onnxruntime::VSINPUProviderFactoryCreator::Create(),
+#endif
 #ifdef USE_RKNPU
             onnxruntime::RknpuProviderFactoryCreator::Create(),
 #endif
diff --git a/onnxruntime/python/onnxruntime_pybind_state.cc b/onnxruntime/python/onnxruntime_pybind_state.cc
index 54accf7ed88f3..db32a82ac4361 100644
--- a/onnxruntime/python/onnxruntime_pybind_state.cc
+++ b/onnxruntime/python/onnxruntime_pybind_state.cc
@@ -1180,6 +1180,10 @@ std::unique_ptr<IExecutionProvider> CreateExecutionProviderInstance(
     const auto partitioning_stop_ops_list = session_options.config_options.GetConfigEntry(
         kOrtSessionOptionsConfigNnapiEpPartitioningStopOps);
     return onnxruntime::NnapiProviderFactoryCreator::Create(0, partitioning_stop_ops_list)->CreateProvider();
+#endif
+  } else if (type == kVSINPUExecutionProvider) {
+#ifdef USE_VSINPU
+    return onnxruntime::VSINPUProviderFactoryCreator::Create()->CreateProvider();
 #endif
   } else if (type == kRknpuExecutionProvider) {
 #ifdef USE_RKNPU
diff --git a/onnxruntime/python/onnxruntime_pybind_state_common.h b/onnxruntime/python/onnxruntime_pybind_state_common.h
index b71081bf20efc..995341b0f8dc0 100644
--- a/onnxruntime/python/onnxruntime_pybind_state_common.h
+++ b/onnxruntime/python/onnxruntime_pybind_state_common.h
@@ -440,6 +440,7 @@ std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_ArmNN(
 std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_DML(int device_id);
 std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_Nnapi(
     uint32_t flags, const optional<std::string>& partitioning_stop_ops_list);
+std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_VSINPU();
 std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_Rknpu();
 std::shared_ptr<IExecutionProviderFactory> CreateExecutionProviderFactory_CoreML(uint32_t flags);
 constexpr const char* kDefaultExecutionProviderEntry = "GetProvider";