diff --git a/.github/workflows/build-wasm_of_ocaml.yml b/.github/workflows/build-wasm_of_ocaml.yml
index e0f394dc..61d7616e 100644
--- a/.github/workflows/build-wasm_of_ocaml.yml
+++ b/.github/workflows/build-wasm_of_ocaml.yml
@@ -20,6 +20,7 @@ jobs:
           - 5.00.x
           - 5.01.x
           - 5.02.x
+          - 5.3.0~beta2
         separate_compilation:
           - true
         include:
diff --git a/dune-project b/dune-project
index d21f14b0..8bfe6769 100644
--- a/dune-project
+++ b/dune-project
@@ -139,7 +139,7 @@
  (description
   "Wasm_of_ocaml is a compiler from OCaml bytecode to WebAssembly. It makes it possible to run pure OCaml programs in JavaScript environment like browsers and Node.js")
  (depends
-  (ocaml (and (>= 4.14) (< 5.3)))
+  (ocaml (>= 4.14))
   (js_of_ocaml (= :version))
   (num :with-test)
   (ppx_expect (and (>= v0.14.2) :with-test))
diff --git a/wasm_of_ocaml-compiler.opam b/wasm_of_ocaml-compiler.opam
index b8a5d217..b145d310 100644
--- a/wasm_of_ocaml-compiler.opam
+++ b/wasm_of_ocaml-compiler.opam
@@ -13,7 +13,7 @@ doc: "https://ocsigen.org/js_of_ocaml/latest/manual/overview"
 bug-reports: "https://github.com/ocsigen/js_of_ocaml/issues"
 depends: [
   "dune" {>= "3.17"}
-  "ocaml" {>= "4.14" & < "5.3"}
+  "ocaml" {>= "4.14"}
   "js_of_ocaml" {= version}
   "num" {with-test}
   "ppx_expect" {>= "v0.14.2" & with-test}