diff --git a/backend/src/routes/api/modelRegistries/index.ts b/backend/src/routes/api/modelRegistries/index.ts
new file mode 100644
index 0000000000..4f7891e16c
--- /dev/null
+++ b/backend/src/routes/api/modelRegistries/index.ts
@@ -0,0 +1,180 @@
+import { FastifyReply, FastifyRequest } from 'fastify';
+import { PatchUtils } from '@kubernetes/client-node';
+import { secureAdminRoute } from '../../../utils/route-security';
+import { KubeFastifyInstance, ModelRegistryKind, RecursivePartial } from '../../../types';
+import { MODEL_REGISTRY_NAMESPACE } from '../../../utils/constants';
+
+export default async (fastify: KubeFastifyInstance): Promise<void> => {
+  fastify.get(
+    '/',
+    secureAdminRoute(fastify)(
+      async (
+        request: FastifyRequest<{ Querystring: { labelSelector: string } }>,
+        reply: FastifyReply,
+      ) => {
+        const { labelSelector } = request.query;
+        try {
+          const response = await fastify.kube.customObjectsApi.listNamespacedCustomObject(
+            'modelregistry.opendatahub.io',
+            'v1alpha1',
+            MODEL_REGISTRY_NAMESPACE,
+            'modelregistries',
+            undefined,
+            undefined,
+            undefined,
+            labelSelector,
+          );
+          return response.body;
+        } catch (e) {
+          fastify.log.error(
+            `ModelRegistries could not be listed, ${e.response?.body?.message || e.message}`,
+          );
+          reply.send(e);
+        }
+      },
+    ),
+  );
+
+  fastify.post(
+    '/',
+    secureAdminRoute(fastify)(
+      async (
+        request: FastifyRequest<{
+          Querystring: { dryRun?: string };
+          Body: ModelRegistryKind;
+        }>,
+        reply: FastifyReply,
+      ) => {
+        const { dryRun } = request.query;
+        const modelRegistry = request.body;
+        try {
+          const response = await fastify.kube.customObjectsApi.createNamespacedCustomObject(
+            'modelregistry.opendatahub.io',
+            'v1alpha1',
+            MODEL_REGISTRY_NAMESPACE,
+            'modelregistries',
+            request.body,
+            undefined,
+            dryRun,
+          );
+          return response.body;
+        } catch (e) {
+          fastify.log.error(
+            `ModelRegistry ${modelRegistry.metadata.name} could not be created, ${
+              e.response?.body?.message || e.message
+            }`,
+          );
+          reply.send(e);
+        }
+      },
+    ),
+  );
+
+  fastify.get(
+    '/:modelRegistryName',
+    secureAdminRoute(fastify)(
+      async (
+        request: FastifyRequest<{ Params: { modelRegistryName: string } }>,
+        reply: FastifyReply,
+      ) => {
+        const { modelRegistryName } = request.params;
+        try {
+          const response = await fastify.kube.customObjectsApi.getNamespacedCustomObject(
+            'modelregistry.opendatahub.io',
+            'v1alpha1',
+            MODEL_REGISTRY_NAMESPACE,
+            'modelregistries',
+            modelRegistryName,
+          );
+          return response.body;
+        } catch (e) {
+          fastify.log.error(
+            `ModelRegistry ${modelRegistryName} could not be read, ${
+              e.response?.body?.message || e.message
+            }`,
+          );
+          reply.send(e);
+        }
+      },
+    ),
+  );
+
+  fastify.patch(
+    '/:modelRegistryName',
+    secureAdminRoute(fastify)(
+      async (
+        request: FastifyRequest<{
+          Querystring: { dryRun?: string };
+          Params: { modelRegistryName: string };
+          Body: RecursivePartial<ModelRegistryKind>;
+        }>,
+        reply: FastifyReply,
+      ) => {
+        const options = {
+          headers: { 'Content-type': PatchUtils.PATCH_FORMAT_JSON_PATCH },
+        };
+        const { dryRun } = request.query;
+        const { modelRegistryName } = request.params;
+        try {
+          const response = await fastify.kube.customObjectsApi.patchNamespacedCustomObject(
+            'modelregistry.opendatahub.io',
+            'v1alpha1',
+            MODEL_REGISTRY_NAMESPACE,
+            'modelregistries',
+            modelRegistryName,
+            request.body,
+            dryRun,
+            undefined,
+            undefined,
+            options,
+          );
+          return response.body;
+        } catch (e) {
+          fastify.log.error(
+            `ModelRegistry ${modelRegistryName} could not be modified, ${
+              e.response?.body?.message || e.message
+            }`,
+          );
+          reply.send(e);
+        }
+      },
+    ),
+  );
+
+  fastify.delete(
+    '/:modelRegistryName',
+    secureAdminRoute(fastify)(
+      async (
+        request: FastifyRequest<{
+          Querystring: { dryRun?: string };
+          Params: { modelRegistryName: string };
+        }>,
+        reply: FastifyReply,
+      ) => {
+        const { dryRun } = request.query;
+        const { modelRegistryName } = request.params;
+        try {
+          const response = await fastify.kube.customObjectsApi.deleteNamespacedCustomObject(
+            'modelregistry.opendatahub.io',
+            'v1alpha1',
+            MODEL_REGISTRY_NAMESPACE,
+            'modelregistries',
+            modelRegistryName,
+            undefined,
+            undefined,
+            undefined,
+            dryRun,
+          );
+          return response.body;
+        } catch (e) {
+          fastify.log.error(
+            `ModelRegistry ${modelRegistryName} could not be deleted, ${
+              e.response?.body?.message || e.message
+            }`,
+          );
+          reply.send(e);
+        }
+      },
+    ),
+  );
+};
diff --git a/backend/src/routes/api/service/modelregistry/index.ts b/backend/src/routes/api/service/modelregistry/index.ts
index a236548397..b214d3055b 100644
--- a/backend/src/routes/api/service/modelregistry/index.ts
+++ b/backend/src/routes/api/service/modelregistry/index.ts
@@ -1,6 +1,6 @@
 import httpProxy from '@fastify/http-proxy';
 import { KubeFastifyInstance } from '../../../../types';
-import { DEV_MODE } from '../../../../utils/constants';
+import { DEV_MODE, MODEL_REGISTRY_NAMESPACE } from '../../../../utils/constants';
 import { getParam, setParam } from '../../../../utils/proxy';
 
 export default async (fastify: KubeFastifyInstance): Promise<void> => {
@@ -20,7 +20,7 @@ export default async (fastify: KubeFastifyInstance): Promise<void> => {
           // kubectl port-forward -n <namespace> svc/<service-name> <local.port>:<service.port>
           `http://${process.env.MODEL_REGISTRY_SERVICE_HOST}:${process.env.MODEL_REGISTRY_SERVICE_PORT}`
         : // Construct service URL
-          `http://${name}.odh-model-registries.svc.cluster.local:8080`;
+          `http://${name}.${MODEL_REGISTRY_NAMESPACE}.svc.cluster.local:8080`;
 
       // assign the `upstream` param so we can dynamically set the upstream URL for http-proxy
       setParam(request, 'upstream', upstream);
diff --git a/backend/src/types.ts b/backend/src/types.ts
index b487889eeb..927f51cbf9 100644
--- a/backend/src/types.ts
+++ b/backend/src/types.ts
@@ -1029,6 +1029,36 @@ export type TrustyAIKind = K8sResourceCommon & {
 };
 
 export type ModelRegistryKind = K8sResourceCommon & {
+  metadata: {
+    name: string;
+    namespace: string;
+  };
+  spec: {
+    grpc: {
+      port: number;
+    };
+    rest: {
+      port: number;
+      serviceRoute: string;
+    };
+    mysql?: {
+      database: string;
+      host: string;
+      port?: number;
+    };
+    postgres: {
+      database: string;
+      host?: string;
+      passwordSecret?: {
+        key: string;
+        name: string;
+      };
+      port: number;
+      skipDBCreation?: boolean;
+      sslMode?: string;
+      username?: string;
+    };
+  };
   status?: {
     conditions?: K8sCondition[];
   };
diff --git a/backend/src/utils/constants.ts b/backend/src/utils/constants.ts
index 4d39f675f1..a71e41e991 100644
--- a/backend/src/utils/constants.ts
+++ b/backend/src/utils/constants.ts
@@ -141,3 +141,5 @@ export const THANOS_RBAC_PORT = '9092';
 export const THANOS_INSTANCE_NAME = 'thanos-querier';
 export const THANOS_NAMESPACE = 'openshift-monitoring';
 export const LABEL_SELECTOR_DASHBOARD_RESOURCE = `${KnownLabels.DASHBOARD_RESOURCE}=true`;
+
+export const MODEL_REGISTRY_NAMESPACE = 'odh-model-registries';
diff --git a/frontend/src/services/modelRegistryService.ts b/frontend/src/services/modelRegistryService.ts
new file mode 100644
index 0000000000..608412d818
--- /dev/null
+++ b/frontend/src/services/modelRegistryService.ts
@@ -0,0 +1,60 @@
+import axios from 'axios';
+import { ModelRegistryKind } from '~/k8sTypes';
+import { RecursivePartial } from '~/typeHelpers';
+
+export const listModelRegistriesBackend = (
+  labelSelector?: string,
+): Promise<ModelRegistryKind[]> => {
+  const url = '/api/modelRegistries';
+  return axios
+    .get(url, { params: { labelSelector } })
+    .then((response) => response.data.items)
+    .catch((e) => {
+      throw new Error(e.response.data.message);
+    });
+};
+
+export const createModelRegistryBackend = (data: ModelRegistryKind): Promise<ModelRegistryKind> => {
+  const url = '/api/modelRegistries';
+  return axios
+    .post(url, data)
+    .then((response) => response.data)
+    .catch((e) => {
+      throw new Error(e.response.data.message);
+    });
+};
+
+export const getModelRegistryBackend = (modelRegistryName: string): Promise<ModelRegistryKind> => {
+  const url = `/api/modelRegistries/${modelRegistryName}`;
+  return axios
+    .get(url)
+    .then((response) => response.data)
+    .catch((e) => {
+      throw new Error(e.response.data.message);
+    });
+};
+
+export const updateModelRegistryBackend = (
+  modelRegistryName: string,
+  patch: RecursivePartial<ModelRegistryKind>,
+): Promise<ModelRegistryKind> => {
+  const url = `/api/modelRegistries/${modelRegistryName}`;
+  return axios
+    .patch(url, patch)
+    .then((response) => response.data)
+    .catch((e) => {
+      throw new Error(e.response.data.message);
+    });
+};
+
+export const deleteModelRegistryBackend = (
+  modelRegistryName: string,
+): Promise<ModelRegistryKind> => {
+  const url = `/api/modelRegistries/${modelRegistryName}`;
+  return axios
+    .delete(url)
+    .then((response) => response.data)
+    .catch((e) => {
+      throw new Error(e.response.data.message);
+    });
+};
diff --git a/manifests/base/cluster-role.yaml b/manifests/base/cluster-role.yaml
index c816375095..510bab4f33 100644
--- a/manifests/base/cluster-role.yaml
+++ b/manifests/base/cluster-role.yaml
@@ -180,3 +180,15 @@ rules:
       - get
     resources:
       - dscinitializations
+  - apiGroups:
+      - modelregistry.opendatahub.io
+    verbs:
+      - get
+      - list
+      - watch
+      - create
+      - update
+      - patch
+      - delete
+    resources:
+      - modelregistries