From 122ddbdda2964f2d245c9755ad093257185dcef3 Mon Sep 17 00:00:00 2001
From: Samuele Cancellieri
 <32717860+samuelecancellieri@users.noreply.github.com>
Date: Mon, 6 Sep 2021 09:52:34 +0200
Subject: [PATCH] fix typo in pam search

---
 sourceCode/CRISPRofiler/pam_searching.cpp | 2 +-
 1 file changed, 1 insertion(+), 1 deletion(-)

diff --git a/sourceCode/CRISPRofiler/pam_searching.cpp b/sourceCode/CRISPRofiler/pam_searching.cpp
index c7f5951..85b6e55 100755
--- a/sourceCode/CRISPRofiler/pam_searching.cpp
+++ b/sourceCode/CRISPRofiler/pam_searching.cpp
@@ -625,7 +625,7 @@ void searchPAMonGenome(string pam_sequence, int pam_len, string genome_sequence,
 			{
 				if ((nt <= (genome_sequence.length() - (pam_len + max_bulges)))) //save the pam position only if possible for a guide to attach that position(avoid out of bound)
 				{
-					pamindicesreverse.push_back(-nt);
+					pamindicesreverse.push_back(nt);
 				}
 			}
 			if (found_negative)