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Document selfing/cloning rate fuzziness #124

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jeromekelleher opened this issue Apr 11, 2022 · 3 comments
Open

Document selfing/cloning rate fuzziness #124

jeromekelleher opened this issue Apr 11, 2022 · 3 comments

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@jeromekelleher
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Pragmatically we can't enforce that selfing and cloning must be with or without replacment and so we should remain agnostic.

It's a 1/N effect anyway, which is usually considered negligible.

Related to #43 #33

@MattHartfield
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Might be worth also noting that there's also a 'residual cloning' effect; even with cloning_rate = 0, a cloned offspring will be produced with probability 1/2N

@apragsdale
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even with cloning_rate = 0, a cloned offspring will be produced with probability 1/2N

Is that the case? I guess I don't know cloning models too well, but I thought that cloning would occur with probability cloning_rate, in which case you pick a single parent and fully copy its genome (without any recombination) into its offspring. If cloning rate is zero, even if you pick the same parent twice (i.e., a selfing event), meiosis still occurs, but you'd never have the case where an individuals entire genome is copied in full from one generation to the next.

@MattHartfield
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Admittedly the logic I outlined above was for the case with no recombination, I was working on the probability that a neutral WF model will 'choose' the second allele copy from a diploid individual, conditional on the first already being chosen for an offspring.

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