diff --git a/python/dist/BUILD.bazel b/python/dist/BUILD.bazel
index cb913fc8cf71e..2dc9d1267edfa 100644
--- a/python/dist/BUILD.bazel
+++ b/python/dist/BUILD.bazel
@@ -84,6 +84,27 @@ config_setting(
     },
 )
 
+# s390x support is community-maintained and not officially supported. We do not
+# publish s390x wheels.
+config_setting(
+    name = "linux_s390x_release_unused",
+    flag_values = {
+        "//toolchain:release": "True",
+    },
+    values = {"cpu": "linux-s390x"},
+)
+
+config_setting(
+    name = "linux_s390x_local_unused",
+    constraint_values = [
+        "@platforms//os:linux",
+        "@platforms//cpu:s390x",
+    ],
+    flag_values = {
+        "//toolchain:release": "False",
+    },
+)
+
 config_setting(
     name = "osx_x86_64_release",
     flag_values = {
@@ -326,6 +347,8 @@ py_wheel(
         ":linux_x86_64_release": "manylinux2014_x86_64",
         ":linux_aarch64_local": "linux_aarch64",
         ":linux_aarch64_release": "manylinux2014_aarch64",
+        ":linux_s390x_local_unused": "linux_s390x",
+        ":linux_s390x_release_unused": "manylinux2014_s390x",
         ":osx_universal2": "macosx_10_9_universal2",
         ":osx_aarch64": "macosx_11_0_arm64",
         ":windows_x86_32": "win32",
diff --git a/python/dist/dist.bzl b/python/dist/dist.bzl
index 061125ede6376..7c9095e2659ec 100644
--- a/python/dist/dist.bzl
+++ b/python/dist/dist.bzl
@@ -29,6 +29,7 @@ def _get_suffix(limited_api, python_version, cpu):
             "linux-aarch_64": "aarch64-linux-gnu",
             "linux-x86_64": "x86_64-linux-gnu",
             "k8": "x86_64-linux-gnu",
+            "s390x": "s390x-linux-gnu",
         }
 
         return ".cpython-{}-{}.{}".format(