diff --git a/micropip/_compat_in_pyodide.py b/micropip/_compat_in_pyodide.py
index e47aadf..0e1d2b9 100644
--- a/micropip/_compat_in_pyodide.py
+++ b/micropip/_compat_in_pyodide.py
@@ -1,4 +1,7 @@
+from asyncio import CancelledError
+from collections.abc import Awaitable, Callable
 from pathlib import Path
+from typing import TYPE_CHECKING, Concatenate, ParamSpec, TypeVar
 from urllib.parse import urlparse
 
 from pyodide._package_loader import get_dynlibs
@@ -7,7 +10,7 @@
 
 try:
     import pyodide_js
-    from js import Object
+    from js import AbortController, AbortSignal, Object
     from pyodide_js import loadedPackages, loadPackage
     from pyodide_js._api import (  # type: ignore[import]
         loadBinaryFile,
@@ -21,21 +24,45 @@
         raise
     # Otherwise, this is pytest test collection so let it go.
 
+if IN_BROWSER or TYPE_CHECKING:
+    P = ParamSpec("P")
+    T = TypeVar("T")
 
-async def fetch_bytes(url: str, kwargs: dict[str, str]) -> bytes:
+    def _abort_on_cancel(
+        func: Callable[Concatenate[AbortSignal, P], Awaitable[T]],
+    ) -> Callable[P, Awaitable[T]]:
+        """inject an AbortSignal as the first argument"""
+
+        async def wrapper(*args: P.args, **kwargs: P.kwargs) -> T:
+            controller = AbortController.new()
+            try:
+                return await func(controller.signal, *args, **kwargs)
+            except CancelledError:
+                controller.abort()
+                raise
+
+        return wrapper
+
+else:
+    _abort_on_cancel = lambda func: lambda *args, **kwargs: func(None, *args, **kwargs)
+
+
+@_abort_on_cancel
+async def fetch_bytes(signal: AbortSignal, url: str, kwargs: dict[str, str]) -> bytes:
     parsed_url = urlparse(url)
     if parsed_url.scheme == "emfs":
         return Path(parsed_url.path).read_bytes()
     if parsed_url.scheme == "file":
         return (await loadBinaryFile(parsed_url.path)).to_bytes()
 
-    return await (await pyfetch(url, **kwargs)).bytes()
+    return await (await pyfetch(url, **kwargs, signal=signal)).bytes()
 
 
+@_abort_on_cancel
 async def fetch_string_and_headers(
-    url: str, kwargs: dict[str, str]
+    signal: AbortSignal, url: str, kwargs: dict[str, str]
 ) -> tuple[str, dict[str, str]]:
-    response = await pyfetch(url, **kwargs)
+    response = await pyfetch(url, **kwargs, signal=signal)
 
     content = await response.string()
     # TODO: replace with response.headers when pyodide>= 0.24 is released
diff --git a/micropip/_compat_not_in_pyodide.py b/micropip/_compat_not_in_pyodide.py
index 137ec1d..dac34c0 100644
--- a/micropip/_compat_not_in_pyodide.py
+++ b/micropip/_compat_not_in_pyodide.py
@@ -74,7 +74,7 @@ def __get__(self, attr):
 REPODATA_INFO: dict[str, str] = {}
 
 
-def loadPackage(packages: str | list[str]) -> None:
+async def loadPackage(packages: str | list[str]) -> None:
     pass
 
 
diff --git a/micropip/transaction.py b/micropip/transaction.py
index bbc91e2..73adaee 100644
--- a/micropip/transaction.py
+++ b/micropip/transaction.py
@@ -48,11 +48,17 @@ async def gather_requirements(
         self,
         requirements: list[str] | list[Requirement],
     ) -> None:
-        requirement_promises = []
-        for requirement in requirements:
-            requirement_promises.append(self.add_requirement(requirement))
-
-        await asyncio.gather(*requirement_promises)
+        futures: list[asyncio.Future] = []
+        try:
+            for requirement in requirements:
+                futures.append(asyncio.ensure_future(self.add_requirement(requirement)))
+            await asyncio.gather(*futures)
+        except ValueError:
+            if not self.keep_going:
+                for future in futures:
+                    if not future.done():
+                        future.cancel()
+            raise
 
     async def add_requirement(self, req: str | Requirement) -> None:
         if isinstance(req, Requirement):