diff --git a/contributors.yml b/contributors.yml
index 1c035b6794..c221586557 100644
--- a/contributors.yml
+++ b/contributors.yml
@@ -231,6 +231,7 @@
 - kigawas
 - kilavvy
 - kiliman
+- KimHyeongRae0
 - kirillgroshkov
 - kkirsche
 - kno-raziel
diff --git a/integration/vite-dev-test.ts b/integration/vite-dev-test.ts
index de9d1c7fe2..b3f749fcc8 100644
--- a/integration/vite-dev-test.ts
+++ b/integration/vite-dev-test.ts
@@ -511,4 +511,65 @@ test.describe("Vite dev", () => {
       });
     });
   }
+
+  test("does not prebundle RSC server-only route imports in the client optimizer", async ({
+    page,
+    dev,
+  }) => {
+    let files: Files = async ({ port }) => ({
+      "react-router.config.ts": reactRouterConfig({
+        future: { unstable_optimizeDeps: true },
+      }),
+      "vite.config.ts": await viteConfig.basic({
+        port,
+        templateName: "rsc-vite-framework",
+      }),
+      "app/routes/_index.tsx": tsx`
+        import { readServerSecret } from "rsc-server-only-package";
+
+        export async function loader() {
+          return { secret: readServerSecret() };
+        }
+
+        export default function IndexRoute() {
+          return <h1 data-route>Index route</h1>;
+        }
+      `,
+      "node_modules/rsc-server-only-package/package.json": JSON.stringify({
+        name: "rsc-server-only-package",
+        version: "1.0.0",
+        type: "module",
+        main: "index.js",
+      }),
+      "node_modules/rsc-server-only-package/index.js": tsx`
+        export function readServerSecret() {
+          return "server-only";
+        }
+      `,
+    });
+
+    let { cwd, port } = await dev(files, "rsc-vite-framework");
+
+    await page.goto(`http://localhost:${port}/`);
+    await expect(page.locator("[data-route]")).toHaveText("Index route");
+
+    let metadataPath = path.join(cwd, "node_modules/.vite/deps/_metadata.json");
+
+    await expect
+      .poll(async () => {
+        try {
+          return await fs.readFile(metadataPath, "utf8");
+        } catch {
+          return "";
+        }
+      })
+      .not.toBe("");
+
+    let clientDeps = [
+      await fs.readFile(metadataPath, "utf8"),
+      ...(await fs.readdir(path.dirname(metadataPath))),
+    ].join("\n");
+
+    expect(clientDeps).not.toMatch(/rsc[-_]server[-_]only[-_]package/);
+  });
 });
diff --git a/packages/react-router-dev/.changes/unstable.rsc-optimize-deps-route-scan.md b/packages/react-router-dev/.changes/unstable.rsc-optimize-deps-route-scan.md
new file mode 100644
index 0000000000..bff7bf5569
--- /dev/null
+++ b/packages/react-router-dev/.changes/unstable.rsc-optimize-deps-route-scan.md
@@ -0,0 +1 @@
+Prevent RSC route module server exports from being scanned by the client dependency optimizer when `future.unstable_optimizeDeps` is enabled.
diff --git a/packages/react-router-dev/__tests__/rsc-virtual-route-modules-test.ts b/packages/react-router-dev/__tests__/rsc-virtual-route-modules-test.ts
index 0d46cab2f0..01086932bc 100644
--- a/packages/react-router-dev/__tests__/rsc-virtual-route-modules-test.ts
+++ b/packages/react-router-dev/__tests__/rsc-virtual-route-modules-test.ts
@@ -1,7 +1,10 @@
 import * as assert from "node:assert";
 import * as ts from "typescript";
 
-import { virtualRouteModulesPlugin } from "../vite/rsc/virtual-route-modules";
+import {
+  createClientRouteModuleForOptimizeDepsScan,
+  virtualRouteModulesPlugin,
+} from "../vite/rsc/virtual-route-modules";
 
 const plugin = virtualRouteModulesPlugin({
   enforceSplitRouteModules: () => false,
@@ -587,3 +590,43 @@ describe("client-route-module=HydrateFallback", () => {
     );
   });
 });
+
+describe("optimizeDeps scan", () => {
+  it("removes server-only route exports before scanning client deps", () => {
+    let transformed = createClientRouteModuleForOptimizeDepsScan(js`
+      import { clientOnly } from "./client";
+      import { serverOnly } from "server-only-package";
+      import { shared } from "./shared";
+
+      export async function loader() {
+        return serverOnly();
+      }
+
+      export async function action() {
+        return serverOnly();
+      }
+
+      export function ServerComponent() {
+        return serverOnly();
+      }
+
+      export const meta = () => [{ title: shared }];
+
+      export default function Route() {
+        return clientOnly(shared);
+      }
+    `);
+
+    expect(transformed.code).toContain(
+      'import { clientOnly } from "./client";',
+    );
+    expect(transformed.code).toContain('import { shared } from "./shared";');
+    expect(transformed.code).toContain("export const meta");
+    expect(transformed.code).toContain("export default function Route");
+    expect(transformed.code).not.toContain("server-only-package");
+    expect(transformed.code).not.toContain("serverOnly");
+    expect(transformed.code).not.toContain("loader");
+    expect(transformed.code).not.toContain("action");
+    expect(transformed.code).not.toContain("ServerComponent");
+  });
+});
diff --git a/packages/react-router-dev/vite/rsc/plugin.ts b/packages/react-router-dev/vite/rsc/plugin.ts
index 14a15d3544..0ab1edeffb 100644
--- a/packages/react-router-dev/vite/rsc/plugin.ts
+++ b/packages/react-router-dev/vite/rsc/plugin.ts
@@ -23,8 +23,12 @@ import {
 } from "../vite";
 import { hasDependency } from "../has-dependency";
 import { getOptimizeDepsEntries } from "../optimize-deps-entries";
+import { resolveRelativeRouteFilePath } from "../resolve-relative-route-file-path";
 import { createVirtualRouteConfig } from "./virtual-route-config";
-import { virtualRouteModulesPlugin } from "./virtual-route-modules";
+import {
+  createClientRouteModuleForOptimizeDepsScan,
+  virtualRouteModulesPlugin,
+} from "./virtual-route-modules";
 import { loadDotenv } from "../load-dotenv";
 import { validatePluginOrder } from "../plugins/validate-plugin-order";
 import { warnOnClientSourceMaps } from "../plugins/warn-on-client-source-maps";
@@ -204,6 +208,15 @@ export function reactRouterRSCVitePlugin(): Vite.PluginOption[] {
 
         // Async import here to avoid CJS warnings on the console
         let viteNormalizePath = (await import("vite")).normalizePath;
+        let optimizeDepsEntries = getOptimizeDepsEntries({
+          entryClientFilePath: entries.client,
+          reactRouterConfig: config,
+        });
+        let routeFiles = new Set(
+          Object.values(config.routes).map((route) =>
+            resolveRelativeRouteFilePath(route, config),
+          ),
+        );
 
         return {
           resolve: {
@@ -231,15 +244,20 @@ export function reactRouterRSCVitePlugin(): Vite.PluginOption[] {
             ],
           },
           optimizeDeps: {
-            entries: getOptimizeDepsEntries({
-              entryClientFilePath: entries.client,
-              reactRouterConfig: config,
-            }),
+            entries: optimizeDepsEntries,
             ...defineOptimizeDepsCompilerOptions({
               rolldown: {
                 transform: {
                   jsx: "react-jsx",
                 },
+                plugins: config.future.unstable_optimizeDeps
+                  ? [
+                      createRSCOptimizeDepsRouteModulesPlugin({
+                        routeFiles,
+                        transformToJs,
+                      }),
+                    ]
+                  : [],
               },
               esbuild: {
                 jsx: "automatic",
@@ -796,6 +814,51 @@ function getRootDirectory(viteUserConfig: Vite.UserConfig) {
   return viteUserConfig.root ?? process.env.REACT_ROUTER_ROOT ?? process.cwd();
 }
 
+type RSCOptimizeDepsRouteModulesPlugin = {
+  name: string;
+  transform: {
+    filter: { id: RegExp };
+    handler(
+      code: string,
+      id: string,
+    ): Promise<{ code: string; map: null; moduleType: "js" } | undefined>;
+  };
+};
+
+const jsRouteModuleRE = /\.[cm]?[jt]sx?$/;
+
+function createRSCOptimizeDepsRouteModulesPlugin({
+  routeFiles,
+  transformToJs,
+}: {
+  routeFiles: Set<string>;
+  transformToJs: (code: string, filename: string) => Promise<string>;
+}): RSCOptimizeDepsRouteModulesPlugin {
+  return {
+    name: "react-router:rsc-optimize-deps-route-modules",
+    transform: {
+      filter: { id: jsRouteModuleRE },
+      async handler(code, id) {
+        let filename = id.split("?")[0];
+        let normalizedFilename = getVite().normalizePath(filename);
+
+        if (!routeFiles.has(normalizedFilename)) {
+          return;
+        }
+
+        let js = await transformToJs(code, filename);
+        let generated = createClientRouteModuleForOptimizeDepsScan(js);
+
+        return {
+          code: generated.code,
+          map: null,
+          moduleType: "js",
+        };
+      },
+    },
+  };
+}
+
 const getClientBuildDirectory = (
   reactRouterConfig: ResolvedReactRouterConfig,
 ) => path.join(reactRouterConfig.buildDirectory, "client");
diff --git a/packages/react-router-dev/vite/rsc/virtual-route-modules.ts b/packages/react-router-dev/vite/rsc/virtual-route-modules.ts
index b6382ed55f..16edad9baa 100644
--- a/packages/react-router-dev/vite/rsc/virtual-route-modules.ts
+++ b/packages/react-router-dev/vite/rsc/virtual-route-modules.ts
@@ -365,6 +365,14 @@ ${result}`;
   } satisfies Vite.Plugin;
 }
 
+export function createClientRouteModuleForOptimizeDepsScan(code: string) {
+  const ast = babel.parse(code, {
+    sourceType: "module",
+  });
+  removeExports(ast, SERVER_ROUTE_EXPORTS);
+  return babel.generate(ast);
+}
+
 function createId(
   id: string,
   type: "client-route-module",
diff --git a/packages/react-router-dev/vite/vite.ts b/packages/react-router-dev/vite/vite.ts
index a5db6bb350..0d852f4f57 100644
--- a/packages/react-router-dev/vite/vite.ts
+++ b/packages/react-router-dev/vite/vite.ts
@@ -39,6 +39,12 @@ type OxcCompilerOptions = {
 };
 
 type RolldownJsxOptions = "react-jsx";
+type RolldownOptimizeDepsOptions = {
+  transform: {
+    jsx: RolldownJsxOptions;
+  };
+  plugins?: unknown[];
+};
 
 type OptimizeDepsESBuildOptions = NonNullable<
   DepOptimizationConfig["esbuildOptions"]
@@ -55,14 +61,10 @@ export function defineCompilerOptions(options: {
 }
 
 export function defineOptimizeDepsCompilerOptions(options: {
-  rolldown: {
-    transform: {
-      jsx: RolldownJsxOptions;
-    };
-  };
+  rolldown: RolldownOptimizeDepsOptions;
   esbuild: OptimizeDepsESBuildOptions;
 }):
-  | { rolldownOptions: { transform: { jsx: RolldownJsxOptions } } }
+  | { rolldownOptions: RolldownOptimizeDepsOptions }
   | { esbuildOptions: OptimizeDepsESBuildOptions } {
   let vite = getVite();
   return parseInt(vite.version.split(".")[0], 10) >= 8