diff --git a/src/selkies_gstreamer/__main__.py b/src/selkies_gstreamer/__main__.py
index 0e33db4..e16b9b3 100644
--- a/src/selkies_gstreamer/__main__.py
+++ b/src/selkies_gstreamer/__main__.py
@@ -471,6 +471,12 @@ def main():
     parser.add_argument('--metrics_http_port',
                         default=os.environ.get('SELKIES_METRICS_HTTP_PORT', '8000'),
                         help='Port to start the Prometheus metrics server on')
+    parser.add_argument('--start-after-connect',
+                        default=os.environ.get('SELKIES_START_AFTER_CONNECT', ''),
+                        help='Program or command to run on server after the first client has connected')
+    parser.add_argument('--start-after-disconnect',
+                        default=os.environ.get('SELKIES_START_AFTER_DISCONNECT', ''),
+                        help='Program or command to run on server after the last client has disconnected')
     parser.add_argument('--debug', action='store_true',
                         help='Enable debug logging')
     args = parser.parse_args()
@@ -516,6 +522,12 @@ def main():
     using_webrtc_csv = args.enable_webrtc_statistics.lower() == 'true'
     metrics = Metrics(int(args.metrics_http_port), using_webrtc_csv)
 
+    # Setup commands to run on connect and disconnect
+    if args.start_after_connect != '':
+        os.environ['SELKIES_START_AFTER_CONNECT'] = args.start_after_connect
+    if args.start_after_disconnect != '':
+        os.environ['SELKIES_START_AFTER_DISCONNECT'] = args.start_after_disconnect
+
     # Initialize the signalling client
     using_https = args.enable_https.lower() == 'true'
     using_basic_auth = args.enable_basic_auth.lower() == 'true'
diff --git a/src/selkies_gstreamer/signalling_web.py b/src/selkies_gstreamer/signalling_web.py
index 4f7008a..93de117 100644
--- a/src/selkies_gstreamer/signalling_web.py
+++ b/src/selkies_gstreamer/signalling_web.py
@@ -14,7 +14,6 @@
 #   Author: Nirbheek Chauhan <nirbheek@centricular.com>
 
 import os
-import base64
 import sys
 import ssl
 import logging
@@ -32,6 +31,7 @@
 import hashlib
 import hmac
 import base64
+import subprocess
 
 from pathlib import Path
 from http import HTTPStatus
@@ -277,6 +277,15 @@ async def cleanup_session(self, uid):
                     wso, oaddr, _, _ = self.peers[other_id]
                     del self.peers[other_id]
                     await wso.close()
+            # Run application after last session disconnected
+            try:
+                if 'SELKIES_START_AFTER_DISCONNECT' in os.environ and len(self.sessions) == 0:
+                    if os.environ['SELKIES_START_AFTER_DISCONNECT'] != '':
+                        command = os.environ['SELKIES_START_AFTER_DISCONNECT'].split(' ')
+                        subprocess.Popen(command, stdout=subprocess.DEVNULL,
+                                         stderr=subprocess.DEVNULL)
+            except Exception as e:
+                logger.error('Failed to run SELKIES_START_AFTER_DISCONNECT: {}'.format(e))
 
     async def cleanup_room(self, uid, room_id):
         room_peers = self.rooms[room_id]
@@ -367,6 +376,15 @@ async def connection_handler(self, ws, uid, meta=None):
                 wsc = self.peers[callee_id][0]
                 logger.info('Session from {!r} ({!r}) to {!r} ({!r})'
                       ''.format(uid, raddr, callee_id, wsc.remote_address))
+                # Run application on first session connection
+                try:
+                    if 'SELKIES_START_AFTER_CONNECT' in os.environ and len(self.sessions) == 0:
+                        if os.environ['SELKIES_START_AFTER_CONNECT'] != '':
+                            command = os.environ['SELKIES_START_AFTER_CONNECT'].split(' ')
+                            subprocess.Popen(command, stdout=subprocess.DEVNULL,
+                                             stderr=subprocess.DEVNULL)
+                except Exception as e:
+                    logger.error('Failed to run SELKIES_START_AFTER_CONNECT: {}'.format(e))
                 # Register session
                 self.peers[uid][2] = peer_status = 'session'
                 self.sessions[uid] = callee_id