diff --git a/alembic/autogenerate/rewriter.py b/alembic/autogenerate/rewriter.py
index 68a93dd0..eae01acb 100644
--- a/alembic/autogenerate/rewriter.py
+++ b/alembic/autogenerate/rewriter.py
@@ -4,7 +4,7 @@
 from typing import Callable
 from typing import Iterator
 from typing import List
-from typing import Optional
+from typing import Tuple
 from typing import Type
 from typing import TYPE_CHECKING
 from typing import Union
@@ -23,6 +23,10 @@
     from ..runtime.environment import _GetRevArg
     from ..runtime.migration import MigrationContext
 
+    ProcessRevisionDirectiveFn = Callable[
+        [MigrationContext, _GetRevArg, List["MigrationScript"]], None
+    ]
+
 
 class Rewriter:
     """A helper object that allows easy 'rewriting' of ops streams.
@@ -52,15 +56,21 @@ class Rewriter:
 
     _traverse = util.Dispatcher()
 
-    _chained: Optional[Rewriter] = None
+    _chained: Tuple[Union[ProcessRevisionDirectiveFn, Rewriter], ...] = ()
 
     def __init__(self) -> None:
         self.dispatch = util.Dispatcher()
 
-    def chain(self, other: Rewriter) -> Rewriter:
+    def chain(
+        self,
+        other: Union[
+            ProcessRevisionDirectiveFn,
+            Rewriter,
+        ],
+    ) -> Rewriter:
         """Produce a "chain" of this :class:`.Rewriter` to another.
 
-        This allows two rewriters to operate serially on a stream,
+        This allows two or more rewriters to operate serially on a stream,
         e.g.::
 
             writer1 = autogenerate.Rewriter()
@@ -89,7 +99,7 @@ def add_column_idx(context, revision, op):
         """
         wr = self.__class__.__new__(self.__class__)
         wr.__dict__.update(self.__dict__)
-        wr._chained = other
+        wr._chained += (other,)
         return wr
 
     def rewrites(
@@ -146,8 +156,8 @@ def __call__(
         directives: List[MigrationScript],
     ) -> None:
         self.process_revision_directives(context, revision, directives)
-        if self._chained:
-            self._chained(context, revision, directives)
+        for process_revision_directives in self._chained:
+            process_revision_directives(context, revision, directives)
 
     @_traverse.dispatch_for(ops.MigrationScript)
     def _traverse_script(
diff --git a/docs/build/unreleased/1337.rst b/docs/build/unreleased/1337.rst
new file mode 100644
index 00000000..2660e831
--- /dev/null
+++ b/docs/build/unreleased/1337.rst
@@ -0,0 +1,7 @@
+.. change::
+    :tags: bug, autogenerate
+    :tickets: 1337
+
+    Fixes `autogenerate.Rewriter` so that more than two instances could be
+    chained together correctly, and `process_revision_directives` callable
+    could also be chained.
diff --git a/tests/test_script_production.py b/tests/test_script_production.py
index 3b5a6f60..7b7db814 100644
--- a/tests/test_script_production.py
+++ b/tests/test_script_production.py
@@ -933,6 +933,11 @@ def add_column_idx(context, revision, op):
             idx_op = ops.CreateIndexOp("ixt", op.table_name, [op.column.name])
             return [op, idx_op]
 
+        def process_revision_directives(context, revision, generate_revisions):
+            generate_revisions[0].downgrade_ops = ops.DowngradeOps(
+                ops=[ops.DropColumnOp("t1", "x")]
+            )
+
         directives = [
             ops.MigrationScript(
                 util.rev_id(),
@@ -956,7 +961,8 @@ def add_column_idx(context, revision, op):
         ]
 
         ctx, rev = mock.Mock(), mock.Mock()
-        writer1.chain(writer2)(ctx, rev, directives)
+        writer = writer1.chain(process_revision_directives).chain(writer2)
+        writer(ctx, rev, directives)
 
         eq_(
             autogenerate.render_python_code(directives[0].upgrade_ops),
@@ -970,6 +976,13 @@ def add_column_idx(context, revision, op):
             "    # ### end Alembic commands ###",
         )
 
+        eq_(
+            autogenerate.render_python_code(directives[0].downgrade_ops),
+            "# ### commands auto generated by Alembic - please adjust! ###\n"
+            "    op.drop_column('t1', 'x')\n"
+            "    # ### end Alembic commands ###",
+        )
+
     def test_no_needless_pass(self):
         writer1 = autogenerate.Rewriter()