tcbb.bio

VARS: pRB, E2F1

PARAMS: y_pRB,0.0,1.0

CONSTS: k1,1; k2,1.6; y_E2F1,0.1; a,0.04; kp,0.05

VAR_POINTS: pRB: 1500, 10; E2F1: 1500, 10

EQ: pRB = k1*Hillp(E2F1,0.5,1,0,1)*Hillm(pRB,0.5,1,1,0) - y_pRB*pRB
EQ: E2F1 = kp + k2*a*a*0.0625*Hillm(E2F1,4,2,1,0)*Hillm(pRB,5,1,1,0) + k2*Hillp(E2F1,4,2,0,1)*Hillm(pRB,5,1,1,0) - y_E2F1*E2F1

THRES: pRB:  0, 3, 7, 10
THRES: E2F1: 0, 0.5, 2, 2.5, 4, 6, 7.5, 10, 15

INIT: pRB: 3, 7; E2F1: 2, 6