region-of-interest band-pass-filter statistical-significance-test metrics-evaluation diffraction-limited-spots scale-space-feature-detection total-internal-reflection-fluorescence-micscopy epifluorescence-microscopy fluorescent-speckle-microscopy low-signal-to-noise-ratio subresolution-cluster-of-fluorophores speckle-modulation-analysis imaging-technique-evaluation imaging-quality-metrics gaussian-spatial-frequencies-filtering 2d-convolution-operator image-noise-reduction bessel-function-to-gaussian-fitting vinculin latrunculin

feature-detection biological-data-analysis benchmark-framework feature-tracking live-cell-imaging ground-truth graphical-user-interface false-positive false-negative biological-data-visualization time-lapse-dataset software-benchmarking epifluorescence-microscopy benchmarking-metrics fluorescent-speckle-microscopy low-signal-to-noise-ratio software-evaluation subresolution-cluster-of-fluorophores algorithm-validation wide-field-microscopy

motion-detection biomedical-image-processing piecewise-polynomial spline-curves fluorescent-speckle-microscopy automated-kymograph time-lapse-image-sequence visualize-motion-of-fluoresecnt-speckles represent-dynamic-processes-on-one-image greyscale-image-gradient kymograph-slope-represents-speed visualize-biological-processes display-intensity-over-time 2d-representation-position-vs-time curve-trajectory-tracing molecular-cargo-motion-analysis low-signal-to-noise-ratio interpolating-curved-tracks spline-curve-mathematically-interpolated cubic-spline-data-interpolation

inflection-point bessel-function intensity-curvature jacobian-matrix diffraction-limited-spots difference-of-gaussian scale-space-feature-detection resolution-limit low-snr fluorescent-speckle-microscopy point-spread-function-fitting objective-function-optimization generalized-sparrow-limit detection-success-rate change-of-sign-2nd-derivative airy-disk-modeling subresolution-cluster-fluorophores feature-fusion-due-to-noise computationally-inexpensive-detection

drug-repurposing line-intersection drug-resistance center-of-mass system-of-linear-equations diophantine-equations sensitizing-drugs mitotic-inhibitors fluorescent-speckle-microscopy dynein-targeting meiotic-spindle spindle-pole-motion microtubule-growth-trajectory end-binding-protein stathmin-oncoprotein-18 microtubule-nucleation microtubule-minus-end microtubule-dynamics microtubule-regulation minus-end-directed-motors

edge-detection image-segmentation motion-analysis cell-division jacobian-matrix mitotic-cells-segmentation difference-of-gaussian protein-translocation local-gradient texture-filter fluorescent-speckle-microscopy ratio-of-eigenvalues wrapped-around-colormap orientation-sensetive-filter scale-space-speckles local-flow-direction hierarchical-feature-detection local-motion-orientation biological-function-analysis mitotic-spindle