Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Normalization of .hic files #62

Open
aminakur opened this issue Aug 30, 2023 · 1 comment
Open

Normalization of .hic files #62

aminakur opened this issue Aug 30, 2023 · 1 comment

Comments

@aminakur
Copy link

aminakur commented Aug 30, 2023

I have two unbalanced .hic files generated by Juicer. I used chess-sim with the following command:

chess sim --background-query -p 24 /az_new/az_new.hic@2000@KR \
    /NPB_new/NPB_new.hic@2000@KR \
    az_npb_SBs.bedpe az_npb_syntenic_2kb.tsv

Dies the @kr work in this code? Would it compare the normalized matrices as a result?

@kaukrise
Copy link
Collaborator

CHESS uses FAN-C to load Juicer matrices, so yes, the command above should compare KR-normalised 2kb resolution matrices.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants