Load .insulation file (File type not recognised)

[Nicolas-Py]

Im having issues with loading my previously generated insulation files. I probably just didn’t include some necessary parameters help would be much appreciated.

i followed the docs on TADs and TAD boundaries.

Insulation scores are calculated and saved to disk using the InsulationScores class. To run a basic insulation score calculation on a Hi-C object, use from_hic:

insulation = fanc.InsulationScores.from_hic(hic_100kb,
                                             [5000000, 1000000, 1500000,
                                              2000000, 2500000, 3000000,
                                              3500000, 4000000],
                                             file_name="architecture/domains/fanc_example_100kb.insulation")

The file created in file_name can later be easily loaded with load().

I tried to load the file into a jupyter notebook like this:

data = fanc.load("../architecture/domains/fanc_example_100kb.insulation")

and got the error
ValueError: File type not recognised (../architecture/domains/fanc_example_100kb.insulation).

Again help would be much appreciated.

(full msg)

---------------------------------------------------------------------------
ValueError                                Traceback (most recent call last)
Cell In[4], line 1
----> 1 data = fanc.load("../architecture/domains/fanc_example_100kb.insulation")

File ~/PycharmProjects/ext-window/.venv/lib/python3.9/site-packages/fanc/tools/load.py:90, in load(file_name, *args, **kwargs)
     87     logger.debug("Not a Juicer file")
     89 logger.debug("Passing the file on to genomic_region.load to try region_based file types")
---> 90 return gr_load(file_name, *args, **kwargs)

File ~/PycharmProjects/ext-window/.venv/lib/python3.9/site-packages/genomic_regions/regions.py:195, in load(file_name, *args, **kwargs)
    192 except (ImportError, RuntimeError) as e:
    193     logger.debug("Not a BigWig file (exception: {})".format(e))
--> 195 raise ValueError("File type not recognised ({}).".format(file_name))

ValueError: File type not recognised (../architecture/domains/fanc_example_100kb.insulation).