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DESCRIPTION
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DESCRIPTION
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Package: enrichTF
Type: Package
Title: Transcription Factors Enrichment Analysis
Version: 1.3.5
Author: Zheng Wei, Zhana Duren, Shining Ma
Maintainer: Zheng Wei <[email protected]>
Description: As transcription factors (TFs)
play a crucial role in regulating the
transcription process through binding on the
genome alone or in a combinatorial manner,
TF enrichment analysis is an efficient and important procedure to
locate the candidate functional TFs from a set of experimentally
defined regulatory regions.
While it is commonly accepted that structurally
related TFs may have similar binding preference to sequences (i.e. motifs)
and one TF may have multiple motifs, TF enrichment analysis is much more
challenging than motif enrichment analysis. Here we present a R package
for TF enrichment analysis
which combine motif enrichment with the PECA model.
License: GPL-3
Encoding: UTF-8
LazyData: FALSE
Depends:
pipeFrame
Imports:
BSgenome,
rtracklayer,
motifmatchr,
TFBSTools,
R.utils,
methods,
JASPAR2018,
GenomeInfoDb,
GenomicRanges,
IRanges,
BiocGenerics,
S4Vectors,
utils,
parallel,
stats,
ggpubr,
heatmap3,
ggplot2,
clusterProfiler,
rmarkdown,
grDevices,
magrittr
Suggests:
knitr,
testthat,
webshot
Collate:
EnrichStep.R
ConnectTargetGene.R
TFsEnrichInRegions.R
FindMotifsInRegions.R
UnzipAndMergeBed.R
TissueOpennessSpecificity.R
TissueOpennessConserve.R
SingleSampleReport.R
GenBackground.R
onLoad.R
untils.R
Method.R
GeneOntology.R
RoxygenNote: 7.0.2
VignetteBuilder: knitr
biocViews: Software, GeneTarget, MotifAnnotation, GraphAndNetwork, Transcription
URL: https://github.com/wzthu/enrichTF
BugReports: https://github.com/wzthu/enrichTF/issues