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Merge pull request #9 from 3mmaRand/fix-omics-1
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fix
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3mmaRand authored Oct 7, 2023
2 parents 6070e50 + 28a0914 commit 8f8fe67
Showing 1 changed file with 13 additions and 7 deletions.
20 changes: 13 additions & 7 deletions omics/week-3/study_before_workshop.qmd
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::: incremental
- find genes important in frog development

- Important means genes that are differentially expressed between the
control and the FGF treated sibling
- Important means the genes that are differentially expressed between
the control-treated and the FGF-treated siblings

- Differentially expressed means the expression on one group is
significantly higher than the other
- Differentially expressed means the expression in one group is
significantly higher than in the other
:::

## 🐸 Guided analysis
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- There are three cell types: LT-HSCs, HSPCs, Progs [These are the
"treaments"]{style="color:#009900"}

- Many cells of each cell type were sequenced: [These are the
- Many cells of each type were sequenced: [These are the
replicates]{style="color:#009900"}

- [155 LT-HSCs, 701 HSPCs, 798 Progs]{style="color:#009900"}
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- Important means genes that are differentially expressed between at
least two cell types

- Differentially expressed means the expression on one group is
significantly higher than the other
- Differentially expressed means the expression in one group is
significantly higher than in the other
:::

## 🐭 Guided analysis
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but are harder to align
- Long-read technologies e.g. Nanopore have lower base accuracy
but are easier to align
:::

# The raw data

## Raw Sequence data

::: incremental
- Sequencing technology is constantly improving

- Optional: You can read more about Sequencing technologies in
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