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lei_2019_37C.cellml
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<?xml version='1.0'?>
<model name="Lei_2019_37C_IKr" xmlns="http://www.cellml.org/cellml/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<units name="ms">
<unit exponent="1" multiplier="0.001" units="second"/>
</units>
<units name="per_mV">
<unit exponent="-1" units="gram"/>
<unit exponent="-2" units="metre"/>
<unit exponent="3" units="second"/>
<unit exponent="1" units="ampere"/>
</units>
<units name="nA">
<unit exponent="1" multiplier="1e-09" units="ampere"/>
</units>
<units name="per_ms">
<unit exponent="-1" multiplier="1000.0" units="second"/>
</units>
<units name="uS">
<unit exponent="-1" multiplier="1e-09" units="gram"/>
<unit exponent="-2" units="metre"/>
<unit exponent="3" units="second"/>
<unit exponent="2" units="ampere"/>
</units>
<units name="mV">
<unit exponent="1" units="gram"/>
<unit exponent="2" units="metre"/>
<unit exponent="-3" units="second"/>
<unit exponent="-1" units="ampere"/>
</units>
<component name="environment">
<variable cmeta:id="time" name="time" public_interface="out" units="ms"/>
</component>
<component name="membrane">
<variable cmeta:id="membrane_voltage" initial_value="-80.0" name="V" public_interface="out" units="mV"/>
</component>
<component name="nernst">
<variable cmeta:id="potassium_reversal_potential" initial_value="-85.0" name="EK" public_interface="out" units="mV"/>
</component>
<component name="ikr">
<variable cmeta:id="membrane_rapid_delayed_rectifier_potassium_current" name="IKr" units="nA"/>
<variable initial_value="0.0" name="y1" units="dimensionless"/>
<variable initial_value="0.0" name="y2" units="dimensionless"/>
<variable initial_value="0.0" name="y3" units="dimensionless"/>
<variable name="y4" units="dimensionless"/>
<variable name="k14" units="per_ms"/>
<variable name="k21" units="per_ms"/>
<variable name="k41" units="per_ms"/>
<variable name="k12" units="per_ms"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kO1" initial_value="2.06469371e-03" name="p1" units="per_ms"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kO2" initial_value="7.17061646e-02" name="p2" units="per_mV"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kC1" initial_value="3.44186257e-05" name="p3" units="per_ms"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kC2" initial_value="6.17661788e-02" name="p4" units="per_mV"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kI1" initial_value="4.17809103e-01" name="p5" units="per_ms"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kI2" initial_value="2.57733544e-02" name="p6" units="per_mV"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kA1" initial_value="4.75152441e-02" name="p7" units="per_ms"/>
<variable cmeta:id="rapid_delayed_rectifier_potassium_channel_kA2" initial_value="2.50856878e-02" name="p8" units="per_mV"/>
<variable cmeta:id="membrane_rapid_delayed_rectifier_potassium_current_conductance" initial_value="0.1524" name="p9" units="uS"/>
<variable name="time" public_interface="in" units="ms"/>
<variable name="V" public_interface="in" units="mV"/>
<variable name="EK" public_interface="in" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKr</ci>
<apply>
<times/>
<ci>p9</ci>
<ci>y3</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>k14</ci>
<apply>
<times/>
<ci>p7</ci>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<ci>p8</ci>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>k21</ci>
<apply>
<times/>
<ci>p3</ci>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<ci>p4</ci>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>k41</ci>
<apply>
<times/>
<ci>p5</ci>
<apply>
<exp/>
<apply>
<times/>
<ci>p6</ci>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>y4</ci>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>y1</ci>
</apply>
<ci>y2</ci>
</apply>
<ci>y3</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y1</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>k12</ci>
</apply>
<ci>y1</ci>
</apply>
<apply>
<times/>
<ci>k21</ci>
<ci>y2</ci>
</apply>
<apply>
<times/>
<ci>k41</ci>
<ci>y4</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k14</ci>
<ci>y1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y3</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>k21</ci>
</apply>
<ci>y3</ci>
</apply>
<apply>
<times/>
<ci>k12</ci>
<ci>y4</ci>
</apply>
<apply>
<times/>
<ci>k14</ci>
<ci>y2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k41</ci>
<ci>y3</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y2</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>k14</ci>
</apply>
<ci>y2</ci>
</apply>
<apply>
<times/>
<ci>k41</ci>
<ci>y3</ci>
</apply>
<apply>
<times/>
<ci>k12</ci>
<ci>y1</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k21</ci>
<ci>y2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>k12</ci>
<apply>
<times/>
<ci>p1</ci>
<apply>
<exp/>
<apply>
<times/>
<ci>p2</ci>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="environment" component_2="ikr"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#time">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#time" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
</rdf:RDF>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#membrane_voltage">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_voltage" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
</rdf:RDF>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#potassium_reversal_potential">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#potassium_reversal_potential" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
</rdf:RDF>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#membrane_rapid_delayed_rectifier_potassium_current">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_rapid_delayed_rectifier_potassium_current" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#rapid_delayed_rectifier_potassium_channel_kO1">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="herg:params#rapid_delayed_rectifier_potassium_channel_kO1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
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<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_rapid_delayed_rectifier_potassium_current_conductance" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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