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README: ChESS Py 1.0.0

ChESS Logo

⚖️ Licence/Legal Advice:

According to the GNU GPL under which these package and his algorithms is licenced - as far as the algorithms are not yet existing in any other products - every derivate of the software has to share the copyright of the original software. Copyright should be given in credential according to GNU GPL in this way:

ChESS Py - The Chemical Similarity Suite for Python, (c) 2025 by Christian Beringer

The software should be cited in any publication like this:

ChESS Chemical Similiarity Suite (v1.0.0 Python), 2025, Christian Beringer, https://github.com/ChrBeringer/ChESS

BibTEX: @misc{chess2025, author = {Christian Beringer}, title = {{ChESS} (v1.0.0 Python) -- Chemical Similarity Suite}, year = {2025}, howpublished = {\url{https://github.com/ChrBeringer/ChESS}}, note = {Open-source chemical similarity toolkit}, }

For further details please check the LICENCE-File!

🤝 Contribution: Pull requests, issues or suggestions are welcome! Instead of a fork I am always open for contribution. Please read the CONTRIBUTING.md to participate.

What is ChESS Py?

ChESS Py (Chemical Similarity Suite for Python) is an open-source package for the analysis, visualization and processing of chemical similarity relationships. The suite provides a centralized collection of tools for investigating molecular similarities in compound sets, supporting structure elucidation, data exploration and structure-activity relationships.

✨ Features

  • Calculation of structural and topological fingerprints
  • Similarity measures & metrics (Tanimoto, Dice, Cosine, etc.)
  • Substance comparison in sets and clusters
  • Tools for the analysis of chemical neighborhoods and similarity networks
  • Integration with chemical formats and standard libraries (RDKit, etc.)
  • Output formats for visualization and export

📦 Areas of application

e.g....

  • QSAR/QSPR modeling
  • Cluster analysis in chemical libraries
  • Structure-activity hypotheses
  • Data exploration in substance databases

##🛠️ Installation

Open Terminal and type: pip install git+https://github.com/ChrBeringer/ChESS.git

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