tldr-seq_v1.4.0

Tailfindr adapted for the TLDR-seq protocol

tailfindr_v1.4

Fixed issues with very long tails being prematurely terminated in cDNA

tailfindr_v1.3

-Added support for SQK-PCS110 cDNA kit
-Made SQK-PCS110 cDNA kit as the default for cDNA
-Fixed rbokeh's empty plots.

tailfindr_v1.2

Fixed a bug that caused the RNA algorithm to fail because the latest Albacore algorithm does not output the start column in the Event table.

tailfindr_v1.1

• Added support for specifying custom primers.

Example code on how to specify custom primers when calling tailfindr:

df <- find_tails(fast5_dir = system.file('extdata', 'cdna', package = 'tailfindr'),
                 save_dir = '~/Downloads/tailfindr_output',
                 csv_filename = 'cdna_tails.csv',
                 num_cores = 4,
                 dna_datatype = 'custom-cdna',
                 front_primer = "TTTCTGTTGGTGCTGATATTGCTGCCATTACGGCCGG",
                 end_primer = "ACTTGCCTGTCGCTCTATCTT")

tailfindr_v1.0

• Estimates polyA tail length in RNA
• Estimates poly(A)/(T) length in cDNA
• Does not all currently allow for specifying custom cDNA primers
• This version was used in the tailfindr paper