otargen 1.1.5
In this new release, several frequently requested query functions from Open Target are added to the package to expand the package functionality in accessing data that are key in evaluating drug targets. In addition, multiple technical bugs has been fixed to increase the efficiency of the previous query functions data retrieval. The added new query functions include:
-
chemblQuery(): This function queries the Open Targets GraphQL API to retrieve ChEMBL data
for a specified gene and disease, including evidence from the ChEMBL datasource.
▶️ These data are key in evaluating the tractability of a target. -
clinvarQuery(): This function queries the Open Targets GraphQL API to retrieve ClinVar data
for a specified gene and disease, including evidence from the NCBI datasource.
▶️ These data are key in evaluating the target MoA and disease biology. -
knownDrugsQuery(): This function queries the Open Targets GraphQL API to retrieve known drugs data
for a specified gene.
▶️ These data are key to evaluate the competitive landscape of a target. -
mousePhenotypesQuery(): This function queries the Open Targets GraphQL API to retrieve mouse phenotypes data
for a specified gene.
▶️ These data are key in evaluating the target validation. -
compGenomicsQuery(): This function queries the Open Targets GraphQL API to retrieve comparative genomics data
for a specified gene.
▶️ These data are key in evaluating the safety of a target.
Citing otargen in important for us 🙋♂️
Please cite otargen if you use it in your research 🙏🏻 : . Bioinformatics.