R has a hard-coded limit for number of connections, which is roughly speaking 128 (and efficiently 125; see R-parallel-Errors). For this reason making large scale clusters for parallel computing is almost impossible in a standard way. To solve this problem one can compile a customised version of R with suitable connection limit. The included in repo shell script shows how to prepare such a customised R distribution from Microsoft R Open sources.
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Guide to compile Microsoft R Open with custom cluster nodes connection limit
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