cascade-pan

pan => Perturb All Nodes (every node in the model is inhibited by a different drug)

Info

We used the druglogics-synergy pipeline executor module (version 1.2.0) on the CASCADE 1.0 and 2.0 topologies, to perform a full drug pairs response analysis. For each network topology, we used a drug panel that had one drug per every node in the corresponding signaling networks and tested every drug combination up to order 2 (so all possible drug pairs).

Results

For the results with all drug pairs, see the cascade1.0_pan and cascade2.0_pan directories respectively.